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Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

For reasons of both performance and energy efficiency, high-performance computing (HPC) hardware is becoming increasingly heterogeneous. The OpenCL framework supports portable programming across a wide range of computing devices and is…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-01 Beau Johnston , Josh Milthorpe

Training Long-Context Large Language Models (LLMs) is challenging, as hybrid training with long-context and short-context data often leads to workload imbalances. Existing works mainly use data packing to alleviate this issue, but fail to…

Machine Learning · Computer Science 2025-10-14 Yongqiang Yao , Jingru Tan , Kaihuan Liang , Feizhao Zhang , Jiahao Hu , Shuo Wu , Yazhe Niu , Ruihao Gong , Dahua Lin , Ningyi Xu

The paper introduces PDSP-Bench, a novel benchmarking system designed for a systematic understanding of performance of parallel stream processing in a distributed environment. Such an understanding is essential for determining how Stream…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-16 Pratyush Agnihotri , Boris Koldehofe , Roman Heinrich , Carsten Binnig , Manisha Luthra

Frontier models increasingly adopt Mixture-of-Experts (MoE) architectures to achieve large-model performance at reduced cost. However, training MoE models on HPC platforms is hindered by large memory footprints, frequent large-scale…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-07 Sajal Dash , Feiyi Wang

As dataset sizes increase, data analysis tasks in high performance computing (HPC) are increasingly dependent on sophisticated dataflows and out-of-core methods for efficient system utilization. In addition, as HPC systems grow, memory…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-01 George K. Thiruvathukal , Cameron Christensen , Xiaoyong Jin , François Tessier , Venkatram Vishwanath

The widespread deployment of large-scale, compute-intensive applications such as high-performance computing, artificial intelligence, and big data is leading to convergence between cloud and high-performance computing infrastructures. Cloud…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-15 Valerio Besozzi , Matteo Della Bartola , Patrizio Dazzi , Marco Danelutto

Earlier-stage evaluations of a new AI architecture/system need affordable benchmarks. Only using a few AI component benchmarks like MLPerfalone in the other stages may lead to misleading conclusions. Moreover, the learning dynamics are not…

Hardware support for high-performance computing (HPC) has so far been subject to significant advances. The pervasiveness of HPC systems, mainly made up with parallel computing units, makes it crucial to spread and vivify effective HPC…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-06 Claude Tadonki

Medical calculators are fundamental to quantitative, evidence-based clinical practice. However, their real-world use is an adaptive, multi-stage process, requiring proactive EHR data acquisition, scenario-dependent calculator selection, and…

Artificial Intelligence · Computer Science 2026-02-02 Yakun Zhu , Yutong Huang , Shengqian Qin , Zhongzhen Huang , Shaoting Zhang , Xiaofan Zhang

Scaling up model depth and size is now a common approach to raise accuracy in many deep learning (DL) applications, as evidenced by the widespread success of multi-billion or even trillion parameter models in natural language processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-05 Kabir Nagrecha , Arun Kumar

The shift towards high-bandwidth networks driven by AI workloads in data centers and HPC clusters has unintentionally aggravated network latency, adversely affecting the performance of communication-intensive HPC applications. As…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-23 Siyuan Shen , Langwen Huang , Marcin Chrapek , Timo Schneider , Jai Dayal , Manisha Gajbe , Robert Wisniewski , Torsten Hoefler

The rapid growth of AI, data-intensive science, and digital twin technologies has driven an unprecedented demand for high-performance computing (HPC) across the research ecosystem. While national laboratories and industrial hyperscalers…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-25 Peng Shu , Junhao Chen , Zhengliang Liu , Huaqin Zhao , Xinliang Li , Tianming Liu

We recognize the emergence of a statistical computing community focused on working with large computing platforms and producing software and applications that exemplify high-performance statistical computing (HPSC). The statistical…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-03 Sameh Abdulah , Mary Lai O. Salvana , Ying Sun , David E. Keyes , Marc G. Genton

This paper presents some of the current challenges in designing deep learning artificial intelligence (AI) and integrating it with traditional high-performance computing (HPC) simulations. We evaluate existing packages for their ability to…

Performance of clustering algorithms is evaluated with the help of accuracy metrics. There is a great diversity of clustering algorithms, which are key components of many data analysis and exploration systems. However, there exist only few…

Data Structures and Algorithms · Computer Science 2019-02-18 Artem Lutov , Mourad Khayati , Philippe Cudré-Mauroux

Understanding research papers remains challenging for foundation models due to specialized scientific discourse and complex figures and tables, yet existing benchmarks offer limited fine-grained evaluation at scale. To address this gap, we…

Computation and Language · Computer Science 2026-05-01 Yelin Chen , Fanjin Zhang , Suping Sun , Yunhe Pang , Yuanchun Wang , Jian Song , Xiaoyan Li , Lei Hou , Shu Zhao , Jie Tang , Juanzi Li

The increasing adoption of heterogeneous platforms that combine CPUs with accelerators such as GPUs in high-performance computing (HPC) introduces new challenges for performance analysis and optimization. Traditional efficiency metrics,…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-30 Ghazal Rahimi , Victor Lopez , Marc Clascà , Joan Vinyals Ylla Català , Jesus Labarta , Marta Garcia-Gasulla

As the Large Hadron Collider (LHC) continues its upward progression in energy and luminosity towards the planned High-Luminosity LHC (HL-LHC) in 2025, the challenges of the experiments in processing increasingly complex events will also…

Instrumentation and Detectors · Physics 2022-10-05 Paul Lujan , Valerie Halyo

Generative AI, in particular large transformer models, are increasingly driving HPC system design in science and industry. We analyze performance characteristics of such transformer models and discuss their sensitivity to the transformer…