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A biological experiment is the most reliable way of assigning function to a protein. However, in the era of high-throughput sequencing, scientists are unable to carry out experiments to determine the function of every single gene product.…

Quantitative Methods · Quantitative Biology 2016-01-07 Iddo Friedberg , Predrag Radivojac

In drug discovery, highly automated high-throughput laboratories are used to screen a large number of compounds in search of effective drugs. These experiments are expensive, so one might hope to reduce their cost by only experimenting on a…

Machine Learning · Computer Science 2025-04-15 Ihor Neporozhnii , Julien Roy , Emmanuel Bengio , Jason Hartford

Test Driven Development (TDD) is one of the major practices of Extreme Programming for which incremental testing and refactoring trigger the code development. TDD has limited adoption in the industry, as it requires more code to be…

Software Engineering · Computer Science 2025-01-15 Moritz Mock , Jorge Melegati , Barbara Russo

Generative artificial intelligence (GenAI) tools have seen rapid adoption among software developers. While adoption rates in the industry are rising, the underlying factors influencing the effective use of these tools, including the depth…

Software Engineering · Computer Science 2026-01-26 Ludwig Felder , Tobias Eisenreich , Mahsa Fischer , Stefan Wagner , Chunyang Chen

Gene and protein networks are very important to model complex large-scale systems in molecular biology. Inferring or reverseengineering such networks can be defined as the process of identifying gene/protein interactions from experimental…

Machine Learning · Computer Science 2017-03-10 Stefano Beretta , Mauro Castelli , Ivo Goncalves , Ivan Merelli , Daniele Ramazzotti

The Transformer architecture has recently gained considerable attention in the field of graph representation learning, as it naturally overcomes several limitations of Graph Neural Networks (GNNs) with customized attention mechanisms or…

Machine Learning · Computer Science 2025-04-01 Jianqing Liang , Min Chen , Jiye Liang

Recent advances in generative artificial intelligence (AI) technologies have been significantly driven by models such as generative adversarial networks (GANs), variational autoencoders (VAEs), and denoising diffusion probabilistic models…

Machine Learning · Computer Science 2024-10-24 Chengyuan Li , Tianyu Zhang , Xusheng Du , Ye Zhang , Haoran Xie

Test Input Generators (TIGs) are crucial to assess the ability of Deep Learning (DL) image classifiers to provide correct predictions for inputs beyond their training and test sets. Recent advancements in Generative AI (GenAI) models have…

Machine Learning · Computer Science 2024-12-24 Maryam , Matteo Biagiola , Andrea Stocco , Vincenzo Riccio

Generative Adversarial Imitation Learning (GAIL) is a powerful and practical approach for learning sequential decision-making policies. Different from Reinforcement Learning (RL), GAIL takes advantage of demonstration data by experts (e.g.,…

Machine Learning · Computer Science 2020-01-14 Minshuo Chen , Yizhou Wang , Tianyi Liu , Zhuoran Yang , Xingguo Li , Zhaoran Wang , Tuo Zhao

Generative Artificial Intelligence (GenAI) applies models and algorithms such as Large Language Model (LLM) and Foundation Model (FM) to generate new data. GenAI, as a promising approach, enables advanced capabilities in various…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-25 Mozhgan Navardi , Romina Aalishah , Yuzhe Fu , Yueqian Lin , Hai Li , Yiran Chen , Tinoosh Mohsenin

In Grammatical Error Correction (GEC), sequence labeling models enjoy fast inference compared to sequence-to-sequence models; however, inference in sequence labeling GEC models is an iterative process, as sentences are passed to the model…

Computation and Language · Computer Science 2021-06-01 Kevin Parnow , Zuchao Li , Hai Zhao

This work studies training generative adversarial networks under the federated learning setting. Generative adversarial networks (GANs) have achieved advancement in various real-world applications, such as image editing, style transfer,…

Machine Learning · Computer Science 2020-07-21 Chenyou Fan , Ping Liu

Machine learning models work better when curated features are provided to them. Feature engineering methods have been usually used as a preprocessing step to obtain or build a proper feature set. In late years, autoencoders (a specific type…

Neural and Evolutionary Computing · Computer Science 2023-01-18 Francisco Charte , Antonio J. Rivera , Francisco Martínez , María J. del Jesus

Context: Responsibility gaps, long-recognized challenges in socio-technical systems where accountability becomes diffuse or ambiguous, have become increasingly pronounced in GenAI-enabled software. The generative and adaptive nature…

Software Engineering · Computer Science 2025-11-18 Zhenyu Mao , Jacky Keung , Yicheng Sun , Yifei Wang , Shuo Liu , Jialong Li

The General AI Challenge is an initiative to encourage the wider artificial intelligence community to focus on important problems in building intelligent machines with more general scope than is currently possible. The challenge comprises…

Artificial Intelligence · Computer Science 2017-08-18 Jan Feyereisl , Matej Nikl , Martin Poliak , Martin Stransky , Michal Vlasak

In social service, administrative burdens and decision-making challenges often hinder practitioners from performing effective casework. Generative AI (GenAI) offers significant potential to streamline these tasks, yet exacerbates concerns…

Human-Computer Interaction · Computer Science 2025-02-28 Yugin Tan , Kai Xin Soh , Renwen Zhang , Jungup Lee , Han Meng , Biswadeep Sen , Yi-Chieh Lee

The deep Convolutional Neural Network (CNN) is the state-of-the-art solution for large-scale visual recognition. Following basic principles such as increasing the depth and constructing highway connections, researchers have manually…

Computer Vision and Pattern Recognition · Computer Science 2017-03-07 Lingxi Xie , Alan Yuille

Recent advancements in graph neural networks (GNNs) for link prediction have introduced sophisticated training techniques and model architectures. However, reliance on outdated baselines may exaggerate the benefits of these new approaches.…

Machine Learning · Computer Science 2025-08-29 Weishuo Ma , Yanbo Wang , Xiyuan Wang , Muhan Zhang

To reduce experimental effort associated with directed protein evolution and to explore the sequence space encoded by mutating multiple positions simultaneously, we incorporate machine learning in the directed evolution workflow.…

Biomolecules · Quantitative Biology 2020-01-07 Zachary Wu , S. B. Jennifer Kan , Russell D. Lewis , Bruce J. Wittmann , Frances H. Arnold

The majority of data-driven wireless research leans heavily on discriminative AI (DAI) that requires vast real-world datasets. Unlike the DAI, Generative AI (GenAI) pertains to generative models (GMs) capable of discerning the underlying…

Networking and Internet Architecture · Computer Science 2024-03-01 Abdulkadir Celik , Ahmed M. Eltawil
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