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Non-parametric maximum likelihood estimation encompasses a group of classic methods to estimate distribution-associated functions from potentially censored and truncated data, with extensive applications in survival analysis. These methods,…

Methodology · Statistics 2021-08-05 Justin D. Tubbs , Lane Guolan Chen , Thuan Quoc Thach , Pak C. Sham

Estimating causal effects on time-to-event outcomes from observational data is particularly challenging due to censoring, limited sample sizes, and non-random treatment assignment. The need for answering such "when-if" questions--how the…

Machine Learning · Computer Science 2025-11-19 Jessy Xinyi Han , Devavrat Shah

Statistical data simulation is essential in the development of statistical models and methods as well as in their performance evaluation. To capture complex data structures, in particular for high-dimensional data, a variety of simulation…

Methodology · Statistics 2023-05-11 Nicholas Schreck , Alla Slynko , Maral Saadati , Axel Benner

The Survival Energy Model (SEM), as originally introduced by Shimizu et al. (2020), is designed to characterize human bioenergetics by employing diffusion processes or inverse Gaussian processes. While parametric models have been employed…

Applications · Statistics 2024-02-12 Daiki Mitsuta , Yasutaka Shimizu

Accurate models of patient survival probabilities provide important information to clinicians prescribing care for life-threatening and terminal ailments. A recently developed class of models - known as individual survival distributions…

Machine Learning · Computer Science 2019-06-27 Samuel Sokota , Ryan D'Orazio , Khurram Javed , Humza Haider , Russell Greiner

The lifetimes of subjects which are left-censored lie below a threshold value or a limit of detection. A popular tool used to handle left-censored data is the reversed hazard rate. In this work, we study the properties and develop…

Statistics Theory · Mathematics 2022-12-27 G. Asha , Durga Vasudevan

Discrete-time hazard models are widely used when event times are measured in intervals or are not precisely observed. While these models can be estimated using standard generalized linear model techniques, they rely on extensive data…

Methodology · Statistics 2025-07-14 Benjamin Müller , Nikolaus Umlauf , Johannes Seiler , Kenneth Harttgen , Stefan Lang

Survival analysis is a statistical framework for modeling time-to-event data. It plays a pivotal role in medicine, reliability engineering, and social science research, where understanding event dynamics even with few data samples is…

Machine Learning · Computer Science 2026-02-03 Alberto Archetti , Eugenio Lomurno , Diego Piccinotti , Matteo Matteucci

Motivated by the classical Susceptible-Infected-Recovered (SIR) epidemic models proposed by Kermack and Mckendrick, we consider a class of stochastic compartmental dynamical systems with a notion of partial ordering among the compartments.…

Populations and Evolution · Quantitative Biology 2019-01-03 Wasiur R. KhudaBukhsh , Boseung Choi , Eben Kenah , Grzegorz A. Rempala

The aim of survival analysis in healthcare is to estimate the probability of occurrence of an event, such as a patient's death in an intensive care unit (ICU). Recent developments in deep neural networks (DNNs) for survival analysis show…

This paper tackles the problem of time-to-event counterfactual survival prediction, aiming to optimize individualized survival outcomes in the presence of heterogeneity and censored data. We propose CURE, a framework that advances…

Simulation is a useful tool in situations where training data for machine learning models is costly to annotate or even hard to acquire. In this work, we propose a reinforcement learning-based method for automatically adjusting the…

Machine Learning · Computer Science 2019-05-15 Nataniel Ruiz , Samuel Schulter , Manmohan Chandraker

Survival analysis is a critical tool for the modelling of time-to-event data, such as life expectancy after a cancer diagnosis or optimal maintenance scheduling for complex machinery. However, current neural network models provide an…

Machine Learning · Statistics 2021-12-06 Fabio Luis de Mello , J Mark Wilkinson , Visakan Kadirkamanathan

Massive sized survival datasets are becoming increasingly prevalent with the development of the healthcare industry. Such datasets pose computational challenges unprecedented in traditional survival analysis use-cases. A popular way for…

Methodology · Statistics 2023-05-09 Nir Keret , Malka Gorfine

merlin can do a lot of things. From simple stuff, like fitting a linear regression or a Weibull survival model, to a three-level logistic mixed effects model, or a multivariate joint model of multiple longitudinal outcomes (of different…

Computation · Statistics 2018-06-07 Michael J. Crowther

Survival analysis is a crucial semi-supervised task in machine learning with numerous real-world applications, particularly in healthcare. Currently, the most common approach to survival analysis is based on Cox's partial likelihood, which…

Machine Learning · Computer Science 2023-04-27 Andre Vauvelle , Benjamin Wild , Aylin Cakiroglu , Roland Eils , Spiros Denaxas

Semiparametric joint models of longitudinal and competing risks data are computationally costly and their current implementations do not scale well to massive biobank data. This paper identifies and addresses some key computational barriers…

Methodology · Statistics 2022-02-10 Shanpeng Li , Ning Li , Hong Wang , Jin Zhou , Hua Zhou , Gang Li

In the context of survival analysis, Marshall and Olkin (1997) introduced families of distributions by adding a scalar parameter to a given survival function, parameterized or not. In that paper, we generalize their approach. We show how it…

Methodology · Statistics 2011-07-21 Damien Bousquet , Jean-Pierre Daurès , Jean-Michel Marin

Survival analysis studies and predicts the time of death, or other singular unrepeated events, based on historical data, while the true time of death for some instances is unknown. Survival trees enable the discovery of complex nonlinear…

Machine Learning · Computer Science 2024-01-10 Tim Huisman , Jacobus G. M. van der Linden , Emir Demirović

Detecting and resolving violations of temporal constraints in real-time systems is both, time-consuming and resource-intensive, particularly in complex software environments. Measurement-based approaches are widely used during development,…

Operating Systems · Computer Science 2025-07-31 Benno Bielmeier , Ralf Ramsauer , Takahiro Yoshida , Wolfgang Mauerer