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Related papers: Clinical Trial Information Extraction with BERT

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Natural language processing (NLP) tasks, ranging from text classification to text generation, have been revolutionised by the pre-trained language models, such as BERT. This allows corporations to easily build powerful APIs by encapsulating…

Computation and Language · Computer Science 2021-03-19 Xuanli He , Lingjuan Lyu , Qiongkai Xu , Lichao Sun

Transformer models have achieved great success across many NLP problems. However, previous studies in automated ICD coding concluded that these models fail to outperform some of the earlier solutions such as CNN-based models. In this paper…

Named Entity Recognition (NER) is a fundamental Natural Language Processing (NLP) task to extract entities from unstructured data. The previous methods for NER were based on machine learning or deep learning. Recently, pre-training models…

Computation and Language · Computer Science 2020-02-21 Yu Wang , Yining Sun , Zuchang Ma , Lisheng Gao , Yang Xu , Ting Sun

This work presents the development and evaluation of an NLP-enabled probabilistic classifier designed to estimate the probability of technical and regulatory success (pTRS) for clinical trials in the field of neuroscience. While…

Machine Learning · Computer Science 2025-12-02 Michael R. Doane

Natural language tasks like Named Entity Recognition (NER) in the clinical domain on non-English texts can be very time-consuming and expensive due to the lack of annotated data. Cross-lingual transfer (CLT) is a way to circumvent this…

Computation and Language · Computer Science 2023-06-08 Xavier Fontaine , Félix Gaschi , Parisa Rastin , Yannick Toussaint

Biomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in natural language processing (NLP), extracting valuable information from biomedical literature has gained…

Computation and Language · Computer Science 2019-10-21 Jinhyuk Lee , Wonjin Yoon , Sungdong Kim , Donghyeon Kim , Sunkyu Kim , Chan Ho So , Jaewoo Kang

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

Named Entity Recognition (NER) or the extraction of concepts from clinical text is the task of identifying entities in text and slotting them into categories such as problems, treatments, tests, clinical departments, occurrences (such as…

Computation and Language · Computer Science 2022-08-31 Namrata Nath , Sang-Heon Lee , Ivan Lee

This chapter presents a practical guide for conducting Sentiment Analysis using Natural Language Processing (NLP) techniques in the domain of tick-borne disease text. The aim is to demonstrate the process of how the presence of bias in the…

Computation and Language · Computer Science 2024-02-23 Teo Susnjak

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

Objective: This study quantifies the capabilities of GPT-3.5 and GPT-4 for clinical named entity recognition (NER) tasks and proposes task-specific prompts to improve their performance. Materials and Methods: We evaluated these models on…

Computation and Language · Computer Science 2024-01-26 Yan Hu , Qingyu Chen , Jingcheng Du , Xueqing Peng , Vipina Kuttichi Keloth , Xu Zuo , Yujia Zhou , Zehan Li , Xiaoqian Jiang , Zhiyong Lu , Kirk Roberts , Hua Xu

Finding concepts in large clinical ontologies can be challenging when queries use different vocabularies. A search algorithm that overcomes this problem is useful in applications such as concept normalisation and ontology matching, where…

Computation and Language · Computer Science 2022-01-04 Duy-Hoa Ngo , Madonna Kemp , Donna Truran , Bevan Koopman , Alejandro Metke-Jimenez

The use of LLMs for natural language processing has become a popular trend in the past two years, driven by their formidable capacity for context comprehension and learning, which has inspired a wave of research from academics and industry…

Computation and Language · Computer Science 2024-04-09 Faren Yan , Peng Yu , Xin Chen

Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…

Human-Computer Interaction · Computer Science 2017-07-10 Gaurav Trivedi , Phuong Pham , Wendy Chapman , Rebecca Hwa , Janyce Wiebe , Harry Hochheiser

This research on data extraction methods applies recent advances in natural language processing to evidence synthesis based on medical texts. Texts of interest include abstracts of clinical trials in English and in multilingual contexts.…

Computation and Language · Computer Science 2020-01-31 Lena Schmidt , Julie Weeds , Julian P. T. Higgins

Named entity recognition is a natural language processing task to recognize and extract spans of text associated with named entities and classify them in semantic Categories. Google BERT is a deep bidirectional language model, pre-trained…

Computation and Language · Computer Science 2020-03-20 Ehsan Taher , Seyed Abbas Hoseini , Mehrnoush Shamsfard

Clinical trial outcome prediction seeks to estimate the likelihood that a clinical trial will successfully reach its intended endpoint. This process predominantly involves the development of machine learning models that utilize a variety of…

Biomolecules · Quantitative Biology 2024-05-14 Chufan Gao , Tianfan Fu , Jimeng Sun

Pre-trained models such as BERT are widely used in NLP tasks and are fine-tuned to improve the performance of various NLP tasks consistently. Nevertheless, the fine-tuned BERT model trained on our protocol corpus still has a weak…

Computation and Language · Computer Science 2020-02-04 Shoubin Li , Wenzao Cui , Yujiang Liu , Xuran Ming , Jun Hu , YuanzheHu , Qing Wang

Named entity recognition (NER) stands as a fundamental and pivotal task within the realm of Natural Language Processing. Particularly within the domain of Biomedical Method NER, this task presents notable challenges, stemming from the…

Computation and Language · Computer Science 2024-07-01 Chen Tang , Bohao Yang , Kun Zhao , Bo Lv , Chenghao Xiao , Frank Guerin , Chenghua Lin

Medication Extraction and Mining play an important role in healthcare NLP research due to its practical applications in hospital settings, such as their mapping into standard clinical knowledge bases (SNOMED-CT, BNF, etc.). In this work, we…

Computation and Language · Computer Science 2024-12-31 Pablo Romero , Lifeng Han , Goran Nenadic
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