English
Related papers

Related papers: SGEN: Single-cell Sequencing Graph Self-supervised…

200 papers

Heterogeneous graph neural networks (HGNNs) have powerful capability to embed rich structural and semantic information of a heterogeneous graph into node representations. Existing HGNNs inherit many mechanisms from graph neural networks…

Machine Learning · Computer Science 2023-09-04 Xiaocheng Yang , Mingyu Yan , Shirui Pan , Xiaochun Ye , Dongrui Fan

Graph convolutional network (GCN) is an emerging neural network approach. It learns new representation of a node by aggregating feature vectors of all neighbors in the aggregation process without considering whether the neighbors or…

Machine Learning · Computer Science 2022-04-01 Li Zhang , Heda Song , Nikolaos Aletras , Haiping Lu

While single-cell RNA sequencing provides an understanding of the transcriptome of individual cells, its high sparsity, often termed dropout, hampers the capture of significant cell-cell relationships. Here, we propose scFP (single-cell…

Computational Engineering, Finance, and Science · Computer Science 2023-07-24 Sukwon Yun , Junseok Lee , Chanyoung Park

Single-cell RNA sequencing (scRNA-seq) reveals cell heterogeneity, with cell clustering playing a key role in identifying cell types and marker genes. Recent advances, especially graph neural networks (GNNs)-based methods, have…

Genomics · Quantitative Biology 2025-10-03 Ping Xu , Zhiyuan Ning , Pengjiang Li , Wenhao Liu , Pengyang Wang , Jiaxu Cui , Yuanchun Zhou , Pengfei Wang

Training a generative model on a single image has drawn significant attention in recent years. Single image generative methods are designed to learn the internal patch distribution of a single natural image at multiple scales. These models…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Idan Kligvasser , Tamar Rott Shaham , Noa Alkobi , Tomer Michaeli

This article considers the problem of 3-dimensional genome reconstruction for single-cell data, and the uniqueness of such reconstructions in the setting of haploid organisms. We consider multiple graph models as representations of this…

Genomics · Quantitative Biology 2025-12-23 Sean Dewar , Georg Grasegger , Kaie Kubjas , Fatemeh Mohammadi , Anthony Nixon

Attempting to fully exploit the rich information of topological structure and node features for attributed graph, we introduce self-supervised learning mechanism to graph representation learning and propose a novel Self-supervised Consensus…

Social and Information Networks · Computer Science 2021-08-12 Changshu Liu , Liangjian Wen , Zhao Kang , Guangchun Luo , Ling Tian

Single-cell sequencing technology maps cells to a high-dimensional space encoding their internal activity. Recently-proposed virtual cell models extend this concept, enriching cells' representations based on patterns learned from…

Quantitative Methods · Quantitative Biology 2025-11-03 William Gilpin

Graph neural networks (GNNs) have been used extensively for addressing problems in drug design and discovery. Both ligand and target molecules are represented as graphs with node and edge features encoding information about atomic elements…

Machine Learning · Computer Science 2021-10-14 Dhananjay Bhaskar , Jackson D. Grady , Michael A. Perlmutter , Smita Krishnaswamy

Clustering is a fundamental task in data analysis. Recently, deep clustering, which derives inspiration primarily from deep learning approaches, achieves state-of-the-art performance and has attracted considerable attention. Current deep…

Machine Learning · Computer Science 2020-02-13 Deyu Bo , Xiao Wang , Chuan Shi , Meiqi Zhu , Emiao Lu , Peng Cui

Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data is a complex challenge that requires capturing the intricate relationships between genes and their regulatory interactions. In this study, we tackle…

Machine Learning · Computer Science 2024-07-26 Sindhura Kommu , Yizhi Wang , Yue Wang , Xuan Wang

Analysis of single-cell RNA sequencing data is often conducted through network projections such as coexpression networks, primarily due to the abundant availability of network analysis tools for downstream tasks. However, this approach has…

Quantitative Methods · Quantitative Biology 2025-12-24 Wan He , Daniel I. Bolnick , Samuel V. Scarpino , Tina Eliassi-Rad

Contemporary approaches to instance segmentation in cell science use 2D or 3D convolutional networks depending on the experiment and data structures. However, limitations in microscopy systems or efforts to prevent phototoxicity commonly…

Computer Vision and Pattern Recognition · Computer Science 2023-01-27 Christopher Z. Eddy , Austin Naylor , Bo Sun

Graph Convolutional Networks (GCNs) and their variants have received significant attention and achieved start-of-the-art performances on various recommendation tasks. However, many existing GCN models tend to perform recursive aggregations…

Information Retrieval · Computer Science 2020-06-09 Yue Xu , Hao Chen , Zengde Deng , Junxiong Zhu , Yanghua Li , Peng He , Wenyao Gao , Wenjun Xu

Multi-dimensional data exploration is a classic research topic in visualization. Most existing approaches are designed for identifying record patterns in dimensional space or subspace. In this paper, we propose a visual analytics approach…

Machine Learning · Computer Science 2021-04-27 Peng Xie , Wenyuan Tao , Jie Li , Wentao Huang , Siming Chen

Graph Convolutional Networks (GCNs) are widely used to improve recommendation accuracy and performance by effectively learning the representations of user and item nodes. However, two major challenges remain: (1) the lack of further…

Information Retrieval · Computer Science 2025-05-15 Tao Huang , Yihong Chen , Wei Fan , Wei Zhou , Junhao Wen

Recent works on representation learning for graph structured data predominantly focus on learning distributed representations of graph substructures such as nodes and subgraphs. However, many graph analytics tasks such as graph…

Artificial Intelligence · Computer Science 2017-07-18 Annamalai Narayanan , Mahinthan Chandramohan , Rajasekar Venkatesan , Lihui Chen , Yang Liu , Shantanu Jaiswal

In this study, we focus on the graph representation learning (a.k.a. network embedding) in attributed graphs. Different from existing embedding methods that treat the incorporation of graph structure and semantic as the simple combination…

Social and Information Networks · Computer Science 2023-05-12 Meng Qin

This paper presents a novel graph-based deep learning model for tasks involving relations between two nodes (edge-centric tasks), where the focus lies on predicting relationships and interactions between pairs of nodes rather than node…

Machine Learning · Computer Science 2025-07-08 Eugenio Borzone , Leandro Di Persia , Matias Gerard

Unsupervised graph representation learning aims to learn low-dimensional node embeddings without supervision while preserving graph topological structures and node attributive features. Previous graph neural networks (GNN) require a large…

Machine Learning · Computer Science 2020-09-04 Yanqiao Zhu , Yichen Xu , Feng Yu , Shu Wu , Liang Wang