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Large Language Models (LLMs) are rapidly becoming ubiquitous both as stand-alone tools and as components of current and future software systems. To enable usage of LLMs in the high-stake or safety-critical systems of 2030, they need to…

Software Engineering · Computer Science 2024-06-13 Sinclair Hudson , Sophia Jit , Boyue Caroline Hu , Marsha Chechik

Context: The software development industry is rapidly adopting machine learning for transitioning modern day software systems towards highly intelligent and self-learning systems. However, the full potential of machine learning for…

Software Engineering · Computer Science 2021-10-18 Saad Shafiq , Atif Mashkoor , Christoph Mayr-Dorn , Alexander Egyed

Over recent years, there has been a rapid development of deep learning (DL) in both industry and academia fields. However, finding the optimal hyperparameters of a DL model often needs high computational cost and human expertise. To…

Neural and Evolutionary Computing · Computer Science 2022-08-24 Nan Li , Lianbo Ma , Guo Yu , Bing Xue , Mengjie Zhang , Yaochu Jin

We propose an approach to formally specifying the behavioral properties of systems that rely on a perception model for interactions with the physical world. The key idea is to introduce embeddings -- mathematical representations of a…

Artificial Intelligence · Computer Science 2025-03-07 Parv Kapoor , Abigail Hammer , Ashish Kapoor , Karen Leung , Eunsuk Kang

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of Ordinary Differential Equations. Alternative approaches based on formal calculi, often derived from process algebras or term…

Applied machine learning (ML) has rapidly spread throughout the physical sciences; in fact, ML-based data analysis and experimental decision-making has become commonplace. We suggest a shift in the conversation from proving that ML can be…

Materials Science · Physics 2021-12-21 Naohiro Fujinuma , Brian L. DeCost , Jason Hattrick-Simpers , Samuel E. Lofland

Natural language is among the most accessible tools for explaining decisions to humans, and large pretrained language models (PLMs) have demonstrated impressive abilities to generate coherent natural language explanations (NLE). The…

Computation and Language · Computer Science 2024-03-26 Zining Zhu , Haoming Jiang , Jingfeng Yang , Sreyashi Nag , Chao Zhang , Jie Huang , Yifan Gao , Frank Rudzicz , Bing Yin

Product classification is a crucial task in international trade, as compliance regulations are verified and taxes and duties are applied based on product categories. Manual classification of products is time-consuming and error-prone, and…

Computation and Language · Computer Science 2024-10-16 Sina Gholamian , Gianfranco Romani , Bartosz Rudnikowicz , Stavroula Skylaki

The extracellular matrix (ECM) is a highly complex structure through which biochemical and mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a scaffold, providing structural support to cells as well as…

Nature has engineered complex designs to achieve advanced properties and functionalities through evolution, over millions of years. Many organisms have adapted to their living environment producing extremely efficient materials and…

Non-Hermitian systems host band degeneracies that are fundamentally distinct from those in Hermitian systems, most notably exceptional points (EPs) where both eigenvalues and eigenvectors coalesce. In three dimensional (3D) non-Hermitian…

Mesoscale and Nanoscale Physics · Physics 2026-03-12 Bin Jiang , Aolong Guo , Qilin Cai , Jian-Hua Jiang

Cell biomechanics involve a great number of complex phenomena that are fundamental to the evolution of life itself and other associated processes, ranging from the very early stages of embryo-genesis to the maintenance of damaged structures…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Juan Olalla-Pombo , Alberto Badías , Miguel Ángel Sanz-Gómez , José María Benítez , Francisco Javier Montáns

We review the computation models for biofilm and bacteria cells, providing perspectives on biofilm's various properties and potential serving as engineering living materials (ELMs), considering the omnipresence of such biological matter.…

Biological Physics · Physics 2022-06-09 Hanfeng Zhai

Evolutionary algorithm research and applications began over 50 years ago. Like other artificial intelligence techniques, evolutionary algorithms will likely see increased use and development due to the increased availability of computation,…

Neural and Evolutionary Computing · Computer Science 2019-06-24 Andrew N. Sloss , Steven Gustafson

Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

Robotics · Computer Science 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

Designing evolutionary algorithms capable of uncovering highly evolvable representations is an open challenge; such evolvability is important because it accelerates evolution and enables fast adaptation to changing circumstances. This paper…

Neural and Evolutionary Computing · Computer Science 2019-07-16 Alexander Gajewski , Jeff Clune , Kenneth O. Stanley , Joel Lehman

Transposable Elements (TEs) or jumping genes are the DNA sequences that have an intrinsic capability to move within a host genome from one genomic location to another. Studies show that the presence of a TE within or adjacent to a…

Machine Learning · Computer Science 2019-08-27 Manisha Panta , Avdesh Mishra , Md Tamjidul Hoque , Joel Atallah

Advanced manufacturing with new bio-derived materials can be achieved faster and more economically with first-principle-based artificial intelligence and machine learning (AI/ML)-derived models and process optimization. Not only is this…

Soft Condensed Matter · Physics 2026-02-20 Rigoberto Advincula , Jihua Chen

Although continuous advances in theoretical modelling of Molecular Communications (MC) are observed, there is still an insuperable gap between theory and experimental testbeds, especially at the microscale. In this paper, the development of…