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The study of precision medicine involves dynamic treatment regimes (DTRs), which are sequences of treatment decision rules recommended by taking patient-level information as input. The primary goal of the DTR study is to identify an optimal…

Methodology · Statistics 2024-12-11 Dan Liu , Wenqing He

Reinforcement Learning (RL) has opened up new opportunities to enhance existing smart systems that generally include a complex decision-making process. However, modern RL algorithms, e.g., Deep Q-Networks (DQN), are based on deep neural…

Machine Learning · Computer Science 2023-06-22 Yang Ni , Danny Abraham , Mariam Issa , Yeseong Kim , Pietro Mercati , Mohsen Imani

Precision medicine aims to tailor therapeutic decisions to individual patient characteristics. This objective is commonly formalized through dynamic treatment regimes, which use statistical and machine learning methods to derive sequential…

Machine Learning · Statistics 2026-03-23 Sophia Yazzourh , Erica E. M. Moodie

The core challenge of offline reinforcement learning (RL) is dealing with the (potentially catastrophic) extrapolation error induced by the distribution shift between the history dataset and the desired policy. A large portion of prior work…

Machine Learning · Computer Science 2023-07-27 Laixi Shi , Robert Dadashi , Yuejie Chi , Pablo Samuel Castro , Matthieu Geist

In an episodic Markov Decision Process (MDP) problem, an online algorithm chooses from a set of actions in a sequence of $H$ trials, where $H$ is the episode length, in order to maximize the total payoff of the chosen actions. Q-learning,…

Machine Learning · Computer Science 2019-07-11 Xu Zhu

This research focused on enhancing post-incident malware forensic investigation using reinforcement learning RL. We proposed an advanced MDP post incident malware forensics investigation model and framework to expedite post incident…

Cryptography and Security · Computer Science 2025-01-08 Dipo Dunsin , Mohamed Chahine Ghanem , Karim Ouazzane , Vassil Vassilev

We investigate the use of Reinforcement Learning for the optimal execution of meta-orders, where the objective is to execute incrementally large orders while minimizing implementation shortfall and market impact over an extended period of…

Trading and Market Microstructure · Quantitative Finance 2025-11-20 Tomas Espana , Yadh Hafsi , Fabrizio Lillo , Edoardo Vittori

Dynamic treatment regimes (DTRs) formalize medical decision-making as a sequence of rules for different stages, mapping patient-level information to recommended treatments. In practice, estimating an optimal DTR using observational data…

Methodology · Statistics 2024-12-11 Jian Sun , Bo Fu , Li Su

Many real-world continuous control problems are in the dilemma of weighing the pros and cons, multi-objective reinforcement learning (MORL) serves as a generic framework of learning control policies for different preferences over…

Machine Learning · Computer Science 2024-07-26 Wei Hung , Bo-Kai Huang , Ping-Chun Hsieh , Xi Liu

Offline reinforcement learning (RL) enables policy learning from fixed datasets without further environment interaction, making it particularly valuable in high-risk or costly domains. Extreme $Q$-Learning (XQL) is a recent offline RL…

Machine Learning · Computer Science 2026-04-15 Xinming Gao , Shangzhe Li , Yujin Cai , Wenwu Yu

Offline reinforcement learning requires reconciling two conflicting aims: learning a policy that improves over the behavior policy that collected the dataset, while at the same time minimizing the deviation from the behavior policy so as to…

Machine Learning · Computer Science 2021-10-13 Ilya Kostrikov , Ashvin Nair , Sergey Levine

Inverse Reinforcement Learning (IRL) -- the problem of learning reward functions from demonstrations of an \emph{expert policy} -- plays a critical role in developing intelligent systems. While widely used in applications, theoretical…

Machine Learning · Statistics 2024-02-13 Lei Zhao , Mengdi Wang , Yu Bai

Deep reinforcement learning can learn effective policies for a wide range of tasks, but is notoriously difficult to use due to instability and sensitivity to hyperparameters. The reasons for this remain unclear. When using standard…

Machine Learning · Computer Science 2020-03-17 Aviral Kumar , Abhishek Gupta , Sergey Levine

Offline or batch reinforcement learning seeks to learn a near-optimal policy using history data without active exploration of the environment. To counter the insufficient coverage and sample scarcity of many offline datasets, the principle…

Machine Learning · Computer Science 2022-06-14 Laixi Shi , Gen Li , Yuting Wei , Yuxin Chen , Yuejie Chi

Reinforcement learning algorithms often require finiteness of state and action spaces in Markov decision processes (MDPs) (also called controlled Markov chains) and various efforts have been made in the literature towards the applicability…

Machine Learning · Computer Science 2023-09-08 Ali Devran Kara , Naci Saldi , Serdar Yüksel

This paper introduces a novel data-driven approach to design a linear quadratic regulator (LQR) using a reinforcement learning (RL) algorithm that does not require a system model. The key contribution is to perform policy iteration (PI) by…

Systems and Control · Electrical Eng. & Systems 2023-11-20 Soroush Asri , Luis Rodrigues

Incorporating high-level knowledge is an effective way to expedite reinforcement learning (RL), especially for complex tasks with sparse rewards. We investigate an RL problem where the high-level knowledge is in the form of reward machines,…

Artificial Intelligence · Computer Science 2022-02-10 Zhe Xu , Ivan Gavran , Yousef Ahmad , Rupak Majumdar , Daniel Neider , Ufuk Topcu , Bo Wu

We study reinforcement learning in infinite-horizon discounted Markov decision processes with continuous state spaces, where data are generated online from a single trajectory under a Markovian behavior policy. To avoid maintaining an…

Machine Learning · Computer Science 2026-03-05 Shengbo Wang

Reinforcement learning is a popular machine learning paradigm which can find near optimal solutions to complex problems. Most often, these procedures involve function approximation using neural networks with gradient based updates to…

Neural and Evolutionary Computing · Computer Science 2020-06-05 Callum Wilson , Annalisa Riccardi , Edmondo Minisci

Average-reward reinforcement learning offers a principled framework for long-term decision-making by maximizing the mean reward per time step. Although Q-learning is a widely used model-free algorithm with established sample complexity in…

Machine Learning · Statistics 2026-01-21 Yuchen Jiao , Jiin Woo , Gen Li , Gauri Joshi , Yuejie Chi
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