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Most unsupervised NLP models represent each word with a single point or single region in semantic space, while the existing multi-sense word embeddings cannot represent longer word sequences like phrases or sentences. We propose a novel…

Computation and Language · Computer Science 2021-12-30 Haw-Shiuan Chang , Amol Agrawal , Andrew McCallum

Protein-protein interactions (PPIs) are essentials for many biological processes where two or more proteins physically bind together to achieve their functions. Modeling PPIs is useful for many biomedical applications, such as vaccine…

Biomolecules · Quantitative Biology 2021-12-10 Yang Xue , Zijing Liu , Xiaomin Fang , Fan Wang

Sentence embedding methods offer a powerful approach for working with short textual constructs or sequences of words. By representing sentences as dense numerical vectors, many natural language processing (NLP) applications have improved…

Computation and Language · Computer Science 2021-10-05 Yuan An , Alexander Kalinowski , Jane Greenberg

This paper proposes a new model for extracting an interpretable sentence embedding by introducing self-attention. Instead of using a vector, we use a 2-D matrix to represent the embedding, with each row of the matrix attending on a…

Computation and Language · Computer Science 2017-03-10 Zhouhan Lin , Minwei Feng , Cicero Nogueira dos Santos , Mo Yu , Bing Xiang , Bowen Zhou , Yoshua Bengio

A method based on mapping a symbolic sequence into a set of patterns (strings resulting from the sequence parsing) is proposed as a tool for the reconstruction of ancestral sequences. The set union of patterns comprises all the patterns…

Genomics · Quantitative Biology 2015-04-16 Bohdan Kozarzewski

In this paper, we present an adaptation of the sequence-to-sequence model for structured output prediction in vision tasks. In this model the output variables for a given input are predicted sequentially using neural networks. The…

Computer Vision and Pattern Recognition · Computer Science 2016-10-25 Georgia Gkioxari , Alexander Toshev , Navdeep Jaitly

In statistical relational learning, the link prediction problem is key to automatically understand the structure of large knowledge bases. As in previous studies, we propose to solve this problem through latent factorization. However, here…

Artificial Intelligence · Computer Science 2016-06-22 Théo Trouillon , Johannes Welbl , Sebastian Riedel , Éric Gaussier , Guillaume Bouchard

Protein inference plays a vital role in the proteomics study. Two major approaches could be used to handle the problem of protein inference; top-down and bottom-up. This paper presents a framework for protein inference, which uses hardware…

Computational Engineering, Finance, and Science · Computer Science 2014-03-07 S. M. Vidanagamachchi , S. D. Dewasurendra , R. G. Ragel

Top-$N$ sequential recommendation models each user as a sequence of items interacted in the past and aims to predict top-$N$ ranked items that a user will likely interact in a `near future'. The order of interaction implies that sequential…

Information Retrieval · Computer Science 2018-09-21 Jiaxi Tang , Ke Wang

Using Answer Set Programming in an Inference-Based approach to Natural Language Semantics

Computation and Language · Computer Science 2007-05-23 Farid Nouioua , Pascal Nicolas

Implicit discourse relations bind smaller linguistic units into coherent texts. Automatic sense prediction for implicit relations is hard, because it requires understanding the semantics of the linked arguments. Furthermore, annotated…

Computation and Language · Computer Science 2022-10-21 Murali Raghu Babu Balusu , Yangfeng Ji , Jacob Eisenstein

Protein secondary structure prediction is an important problem in bioinformatics. Inspired by the recent successes of deep neural networks, in this paper, we propose an end-to-end deep network that predicts protein secondary structures from…

Biomolecules · Quantitative Biology 2016-04-27 Zhen Li , Yizhou Yu

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

We predict asset returns and measure risk premia using a prominent technique from artificial intelligence -- deep sequence modeling. Because asset returns often exhibit sequential dependence that may not be effectively captured by…

Machine Learning · Computer Science 2021-08-23 Lin William Cong , Ke Tang , Jingyuan Wang , Yang Zhang

Protein language models (PLMs) learn contextual representations from protein sequences and are profoundly impacting various scientific disciplines spanning protein design, drug discovery, and structural predictions. One particular research…

Quantitative Methods · Quantitative Biology 2024-02-07 Andreas Dounas , Tudor-Stefan Cotet , Alexander Yermanos

The method of choice to study one-dimensional strongly interacting many body quantum systems is based on matrix product states and operators. Such method allows to explore the most relevant, and numerically manageable, portion of an…

Statistical Mechanics · Physics 2018-10-10 Chu Guo , Zhanming Jie , Wei Lu , Dario Poletti

In this work, we study whether enforcing strict compositional structure in sequence embeddings yields meaningful geometric organization when applied to protein-protein interaction networks. Using Event2Vec, an additive sequence embedding…

Machine Learning · Computer Science 2026-04-02 Antonin Sulc

Protein language models (PLMs) have shown promise in improving the understanding of protein sequences, contributing to advances in areas such as function prediction and protein engineering. However, training these models from scratch…

Machine Learning · Computer Science 2024-12-19 Shivasankaran Vanaja Pandi , Bharath Ramsundar

Predicting the binding affinity of protein protein complexes directly from sequence remains a challenging problem, particularly in the absence of reliable structural information. Here I present ProtT Affinity, a sequence only model that…

Quantitative Methods · Quantitative Biology 2025-11-21 Hongfu Lou

Existing machine learning methods for molecular (e.g., gene) embeddings are restricted to specific tasks or data modalities, limiting their effectiveness within narrow domains. As a result, they fail to capture the full breadth of gene…