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Traditional domain generalization methods often rely on domain alignment to reduce inter-domain distribution differences and learn domain-invariant representations. However, domain shifts are inherently difficult to eliminate, which limits…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuheng Xu , Taiping Zhang

Domain shift is a significant problem in histopathology. There can be large differences in data characteristics of whole-slide images between medical centers and scanners, making generalization of deep learning to unseen data difficult. To…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Karin Stacke , Gabriel Eilertsen , Jonas Unger , Claes Lundström

Recently, considerable effort has been devoted to deep domain adaptation in computer vision and machine learning communities. However, most of existing work only concentrates on learning shared feature representation by minimizing the…

Machine Learning · Computer Science 2019-04-24 Chao Chen , Zhihong Chen , Boyuan Jiang , Xinyu Jin

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

The domain shift between training and testing data presents a significant challenge for training generalizable deep learning models. As a consequence, the performance of models trained with the independent and identically distributed…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Aleksandr Matsun , Dana O. Mohamed , Sharon Chokuwa , Muhammad Ridzuan , Mohammad Yaqub

Domain generalization typically requires data from multiple source domains for model learning. However, such strong assumption may not always hold in practice, especially in medical field where the data sharing is highly concerned and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Quande Liu , Cheng Chen , Qi Dou , Pheng-Ann Heng

The generalization of deep neural networks to unknown domains is a major challenge despite their tremendous progress in recent years. For this reason, the dynamic area of domain generalization (DG) has emerged. In contrast to unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Manuel Schwonberg , Hanno Gottschalk

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

An organ segmentation method that can generalize to unseen contrasts and scanner settings can significantly reduce the need for retraining of deep learning models. Domain Generalization (DG) aims to achieve this goal. However, most DG…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yanwu Xu , Shaoan Xie , Maxwell Reynolds , Matthew Ragoza , Mingming Gong , Kayhan Batmanghelich

Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the…

Machine Learning · Computer Science 2023-09-19 Chris Xing Tian , Haoliang Li , Yufei Wang , Shiqi Wang

Domain-invariant representation learning is a powerful method for domain generalization. Previous approaches face challenges such as high computational demands, training instability, and limited effectiveness with high-dimensional data,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Yuheng Xu , Taiping Zhang

Convolutional Neural Networks (CNNs) show impressive performance in the standard classification setting where training and testing data are drawn i.i.d. from a given domain. However, CNNs do not readily generalize to new domains with…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Nathan Somavarapu , Chih-Yao Ma , Zsolt Kira

Acceleration of machine learning research in healthcare is challenged by lack of large annotated and balanced datasets. Furthermore, dealing with measurement inaccuracies and exploiting unsupervised data are considered to be central to…

Signal Processing · Electrical Eng. & Systems 2019-01-11 Deepta Rajan , David Beymer , Girish Narayan

Tackling domain shifts in multi-centre and multi-vendor data sets remains challenging for cardiac image segmentation. In this paper, we propose a generalisable segmentation framework for cardiac image segmentation in which multi-centre,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Hongwei Li , Jianguo Zhang , Bjoern Menze

Cardiac magnetic resonance imaging (cMRI) is an integral part of diagnosis in many heart related diseases. Recently, deep neural networks have demonstrated successful automatic segmentation, thus alleviating the burden of time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 Peter M. Full , Fabian Isensee , Paul F. Jäger , Klaus Maier-Hein

Background: Synthetic computed tomography (sCT) has been proposed and increasingly clinically adopted to enable magnetic resonance imaging (MRI)-based radiotherapy. Deep learning (DL) has recently demonstrated the ability to generate…

Medical Physics · Physics 2023-07-25 Lotte Nijskens , Cornelis , AT van den Berg , Joost JC Verhoeff , Matteo Maspero

Recognition across domains has recently become an active topic in the research community. However, it has been largely overlooked in the problem of recognition in new unseen domains. Under this condition, the delivered deep network models…

Computer Vision and Pattern Recognition · Computer Science 2020-04-15 Thanh-Dat Truong , Chi Nhan Duong , Khoa Luu , Minh-Triet Tran , Ngan Le

The success of deep learning has set new benchmarks for many medical image analysis tasks. However, deep models often fail to generalize in the presence of distribution shifts between training (source) data and test (target) data. One…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Dwarikanath Mahapatra