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This paper worked towards modeling blood platelets. Blood platelets, also known as thrombocytes, play a key role in blood clotting which is a vital human function. Furthermore, the role of these entities in strokes, myocardial infarctions,…

Cell Behavior · Quantitative Biology 2012-06-05 Vijay Viswanathan , Seetha Pothapragada

A deeper understanding of the influence of common cardiovascular diseases like stenosis, aneurysm or atherosclerosis on the circulatory mechanism is required, to establish new methods for early diagnosis. Different types of simulators were…

Investigating blood flow in the cardiovascular system is crucial for assessing cardiovascular health. Computational approaches offer some non-invasive alternatives to measure blood flow dynamics. Numerical simulations based on traditional…

Numerical Analysis · Mathematics 2024-06-07 Han Zhang , Raymond Chan , Xue-Cheng Tai

Purpose Segmentation of the liver from abdominal computed tomography (CT) image is an essential step in some computer assisted clinical interventions, such as surgery planning for living donor liver transplant (LDLT), radiotherapy and…

Computer Vision and Pattern Recognition · Computer Science 2016-05-11 Fang Lu , Fa Wu , Peijun Hu , Zhiyi Peng , Dexing Kong

Non-invasive measurement of the arterial blood speed gives rise to important healthinformation such as cardio output and blood supplies to vital organs. The magnitude andchange in arterial blood speed are key indicators of the health…

Medical Physics · Physics 2021-10-22 Alex Ce Zhang , Yu-Hwa Lo

Arterial blood pressure is a key vital sign for the health of the human body. As such, accurate and reproducible measurement techniques are necessary for successful diagnosis. Blood pressure measurement is an example of molecular…

Information Theory · Computer Science 2014-10-22 Malcolm Egan , Adam Noel , Yansha Deng , Maged Elkashlan , Trung Q. Duong

Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…

An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Measured cardiac blood flow data provide insights about patient-specific hemodynamics, where many specialized techniques have…

In this paper, we investigate the hemodynamics of a left atrium (LA) by proposing a computational model suitable to provide physically meaningful fluid dynamics indications and detailed blood flow characterization. In particular, we…

Fluid Dynamics · Physics 2022-07-08 Alberto Zingaro , Luca Dede' , Filippo Menghini , Alfio Quarteroni

We show that the recoils of the body caused by cardiac motion and blood circulation provide a noninvasive method capable to display the motions of the heart muscle and the propagation of the pulse wave along aorta and its branches. The…

Medical Physics · Physics 2007-05-23 J. Kriz , P. Seba

Objective: Innovative therapies such as thermoembolization are expected to play an important role in improvising care for patients with diseases such as hepatocellular carcinoma. Thermoembolization is a minimally invasive strategy that…

In this paper, we introduce an adapted one-dimensional (1D) reduced model aimed at analyzing blood flow within stenosed arteries. Differing from the prevailing 1D model \cite{Formaggia2003, Sherwin2003_2, Sherwin2003, Quarteroni2004,…

Numerical Analysis · Mathematics 2024-09-25 Suncica Canic , Shihan Guo , Yifan Wang , Xiaohe Yue , Haibiao Zheng

We performed numerical simulations of blood flow in arteries with a variable stiffness and cross-section at rest using a finite volume method coupled with a hydrostatic reconstruction of the variables at the interface of each mesh cell. The…

Numerical Analysis · Mathematics 2015-09-15 Olivier Delestre , Arthur Ghigo , Jose-Maria Fullana , Pierre-Yves Lagrée

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

We present a Lagrangian analysis of turbulent blood flow in the human left heart using high-fidelity simulations based on a patient-specific anatomical model. Leveraging a fully coupled fluid-structure-electrophysiology interaction (FSEI)…

Fluid Dynamics · Physics 2025-06-13 Fabio Guglietta , Martino Andrea Scarpolini , Francesco Viola , Luca Biferale

Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system. Aim of this review is to provide a compact summary of state of the art 0D-1D…

Medical Physics · Physics 2022-01-03 Stefania Scarsoglio , Luca Ridolfi

Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…

Quantitative Methods · Quantitative Biology 2020-02-21 Megan J. Chambers , Mitchel J. Colebank , M Umar Qureshi , Rachel Clipp , Mette S. Olufsen

The impact of increased stiffness and pulsatile load on the circulation and their influence on heart performance have been documented not only for cardiovascular events but also for ventricular dysfunctions. For this reason, computer models…

Numerical Analysis · Mathematics 2021-11-11 Federica Caforio , Christoph M. Augustin , Jordi Alastruey , Matthias A. F. Gsell , Gernot Plank

Ventricular Fibrillation (VF) is a malignant cardiac arrhythmia and the leading cause of sudden cardiac death, characterized by disorganized, high-frequency ventricular activity that results in the rapid loss of coordinated pump function…

Biological Physics · Physics 2025-11-04 Artemii Remizov , Sergey Lapin

The heart is the central part of the cardiovascular network. Its role is to pump blood to various body organs. Many cardiovascular diseases occur due to an abnormal functioning of the heart. A diseased heart leads to severe complications…

Medical Physics · Physics 2024-11-19 Mahesh S. Nagargoje , Eneko Lazpita , Jesús Garicano-Mena , Soledad Le Clainche
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