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- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…
Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…
Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…
To address the issue of computational efficiency related to the modelling of blood flow in complex networks, we derive a family of nonlinear lumped-parameter models for blood flow in compliant vessels departing from a well-established…
We present a unified mathematical framework for modeling blood and lymph flow in biological vessels, with a particular focus on lymph transport through lymphangions. Starting from first principles, we rigorously derive a system of partial…
Understanding the physics of blood is challenging due to its nature as a suspension of soft particles and the fact that typical problems involve different scales. This is valid also for numerical investigations. In fact, many computational…
Mathematical modeling at the level of the full cardiovascular system requires the numerical approximation of solutions to a one-dimensional nonlinear hyperbolic system describing flow in a single vessel. This model is often simulated by…
One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…
Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…
The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through…
Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…
The dynamical mechanical analysis of blood generally uses models inspired by conventional flows, assuming scale-independent homogeneous flows and without considering fluid-surface boundary interactions. The present experimental study…
Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…
Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…
Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…
Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…
Zero-dimensional cardiovascular models provide a computationally efficient framework for studying global hemodynamic behavior, yet the influence of model complexity on parameter sensitivity remains insufficiently understood. This work…
Around the third week after gestation in embryonic development, the human heart consists only of a valvless tube, unlike a fully developed adult heart, which is multi-chambered. At this stage in development, the heart valves have not formed…
We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…
This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…