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Magnetic vortices existing in soft magnetic nanoparticles with sizes larger than the single-domain diameter can be efficient nano-heaters in biomedical applications. Using micromagnetic numerical simulation we prove that in the optimal…
Assemblies of magnetic nanoparticles show a great potential for application in biomedicine, in particular, in magnetic hyperthermia. However, to achieve desired therapeutic effect in magnetic hyperthermia the assembly of nanoparticles…
Magnetic nanoparticles (MNP's) have become increasingly important in heating applications such as hyperthermia treatment of cancer due to their ability to release heat when a remote external alternating magnetic field is applied. It has…
The performance of magnetic nanoparticles is intimately entwined with their structure, mean size and magnetic anisotropy. Besides, ensembles offer a unique way of engineering the magnetic response by modifying the strength of the dipolar…
Magnetic particle hyperthermia, in which colloidal nanostructures are exposed to an alternating magnetic field, is a promising approach to cancer therapy. Unfortunately, the clinical efficacy of hyperthermia has not yet been optimized.…
We report on the magnetic and hyperthermia properties of iron nanoparticles synthesized by organometallic chemistry. They are 5.5 nm in diameter and display a saturation magnetization close to the bulk one. Magnetic properties are dominated…
We report on the magnetic hyperthermia properties of chemically synthesized ferromagnetic 11 and 16 nm Fe(0) nanoparticles of cubic shape displaying the saturation magnetization of bulk iron. The specific absorption rate measured on 16 nm…
Understanding and predicting the heat released by magnetic nanoparticles is central to magnetic hyperthermia treatment planning. These nanoparticles tend to form aggregates when injected in living tissues, which alters their response to the…
Heating magnetic nanoparticles with high frequency magnetic fields is a topic of interest for biological applications (magnetic hyperthermia) as well as for heterogeneous catalysis. This study shows why FeC NPs of similar structures and…
In the context of magnetic hyperthermia, several physical parameters are used to optimize the heat generation and these include the nanoparticles concentration and the magnitude and frequency of the external AC magnetic field. Here we…
The main idea of magnetic hyperthermia is to increase locally the temperature of the human body by means of injected superparamagnetic nanoparticles. They absorb energy from a time-dependent external magnetic field and transfer it into…
Magnetic hyperthermia is an adjuvant therapy for cancer where injected magnetic nanoparticles are used to transfer energy from the time-dependent applied magnetic field into the surrounding medium. Its main importance is to be able to…
Magnetic nanoparticle-based hyperthermia has emerged as a promising therapeutic modality for treating malignant solid tumors that exhibit resistance to conventional cancer treatments, including chemotherapy and radiation. Despite the…
Magnetic hyperthermia with metallic nanoparticles is a therapeutic strategy that relies on heating cancer cells to levels sufficient to damage or destroy them. After injection, the nanoparticles accumulate in tumor tissues, where they…
This study was undertaken to develop a system for heat transfer simulation for optimization and treatment planning of magnetic hyperthermia treatment (MHT) using magnetic particle imaging (MPI). First, we performed phantom experiments to…
Magnetic nanoparticle hyperthermia is an attractive emerging cancer treatment, but the acting microscopic energy deposition mechanisms are not well understood and optimization suffers. We describe several approximate forms for the…
Iron oxide (e.g., Fe$_3$O$_4$ or Fe$_2$O$_3$) nanoparticles are promising candidates for a variety of biomedical applications ranging from magnetic hyperthermia therapy to drug delivery and bio-detection, due to their superparamagnetism,…
We present a general study of frequency and magnetic field dependence of the specific heat power produced during field-driven hysteresis cycles in magnetic nanoparticles with relevance to hyperthermia applications in biomedicine. Employing…
Nowadays, magnetic hyperthermia constitutes a complementary approach to cancer treatment. The use of magnetic particles as heating mediators, proposed in the 1950s, provides a novel strategy for improving tumor treatment and, consequently,…
Magnetic particle hyperthermia relies on the efficient conversion of magnetic field energy into heat in biomedical applications, yet the microscopic mechanisms governing heat generation within individual particles remain poorly understood.…