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High-resolution imaging of ultracold atoms typically requires custom high numerical aperture (NA) optics, as is the case for quantum gas microscopy. These high NA objectives involve many optical elements each of which contributes to loss…

Quantum Gases · Physics 2021-11-01 Emine Altuntas , Ian B. Spielman

Quantitative lung measures derived from computed tomography (CT) have been demonstrated to improve prognostication in coronavirus disease (COVID-19) patients, but are not part of the clinical routine since required manual segmentation of…

A majority of ultracold atom experiments utilize resonant absorption imaging techniques to obtain the atomic density. To make well-controlled quantitative measurements, the optical intensity of the probe beam must be precisely calibrated in…

Quantum Physics · Physics 2023-05-15 Emine Altuntas , Ian B. Spielman

The goal of the ANAIS-112 experiment, which operates at LSC, is to test in a model independent way the DAMA/LIBRA positive signal using the same target (NaI(Tl) crystals) and technique. Several strategies have been followed in this work to…

Instrumentation and Detectors · Physics 2023-10-12 David Cintas

Digital assays represent a shift from traditional diagnostics and enable the precise detection of low-abundance analytes, critical for early disease diagnosis and personalized medicine, through discrete counting of biomolecular reporters.…

Computational Physics · Physics 2025-12-08 Neil H. Kim , Xiao-Liu Chu , Joseph B. DeGrandchamp , Matthew R. Foreman

Recent work using plasmonic nanosensors in a clinically relevant detection assay reports extreme sensitivity based upon a mechanism termed 'inverse sensitivity', whereby reduction of substrate concentration increases reaction rate, even at…

Quantitative Methods · Quantitative Biology 2017-06-05 Boris Barbour

We study the variation of the electronic properties at the surface of a high temperature superconductor as a function of vacuum conditions in angle resolved photoemission spectroscopy (ARPES) experiments. Normally, under less than ideal…

Superconductivity · Physics 2017-03-21 A. D. Palczewski , T. Kondo , J. S. Wen , G. Z. J. Xu , G. Gu , A. Kaminski

Effective property prediction methods can help accelerate the search for COVID-19 antivirals either through accurate in-silico screens or by effectively guiding on-going at-scale experimental efforts. However, existing prediction tools have…

Quantitative Methods · Quantitative Biology 2020-05-08 Wengong Jin , Regina Barzilay , Tommi Jaakkola

COVID-19 is a new pulmonary disease which is driving stress to the hospitals due to the large number of cases worldwide. Imaging of lungs can play a key role in monitoring of the healthy status. Non-contrast chest computed tomography (CT)…

We optimized the performance of quantum confined Stark effect QCSE based voltage nanosensors. A high throughput approach for single particle QCSE characterization was developed and utilized to screen a library of such nanosensors. Type II…

Mesoscale and Nanoscale Physics · Physics 2021-08-04 Yung Kuo , Jack Li , Xavier Michalet , Alexey Chizhik , Noga Meir , Omri Bar-Elli , Emory Chan , Dan Oron , Joerg Enderlein , Shimon Weiss

We present a capacitance-voltage study for arrays of vertical InAs nanowires. MOS capacitors are obtained by insulating the nanowires with a conformal 10nm HfO2 layer and using a top Cr/Au metallization as one of the capacitor's electrodes.…

The NA62 experiment is a fixed-target experiment at CERN SPS. The main goal of the experiment is to measure the branching ratio of the ultra-rare kaon decay $K^{+}\to\pi^{+}\nu\bar\nu$. The NA62 detector allows also to study other rare kaon…

A molecular and cellular understanding of how SARS-CoV-2 variably infects and causes severe COVID-19 remains a bottleneck in developing interventions to end the pandemic. We sought to use deep learning to study the biology of SARS-CoV-2…

Machine Learning · Computer Science 2020-12-16 Arijit Sehanobish , Neal G. Ravindra , David van Dijk

Recent experiments have demonstrated the ability to optically cool a macroscopic mechanical oscillator to its quantum ground state by means of dynamic backaction. Such experiments allow quantum mechanics to be tested with mesoscopic…

Mesoscale and Nanoscale Physics · Physics 2013-05-10 Jan Gieseler , Bradley Deutsch , Romain Quidant , Lukas Novotny

Recent advancements in nanotechnology have led to the development of surface-enhanced Raman spectroscopy (SERS) based rapid and low-cost technologies for ultra-sensitive label-free detection and identification of molecular analytes. Herein,…

Optically-levitated dielectric particles can serve as ultra-sensitive detectors of feeble forces and torques, as tools for use in quantum information science, and as a testbed for quantum coherence in macroscopic systems. Knowledge of the…

Coronavirus Disease 2019 (COVID-19) is a rapidly emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to the rapid human-to-human transmission of SARS-CoV-2, many healthcare systems…

Machine Learning · Computer Science 2020-12-01 Patrick Schwab , August DuMont Schütte , Benedikt Dietz , Stefan Bauer

The SARS-CoV-2 coronavirus emerged in 2019, causing a COVID-19 pandemic that resulted in 7 million deaths out of 770 million reported cases over the next four years. The global health emergency called for unprecedented efforts to monitor…

The (111) surface of CaF$_2$ has been intensively studied with large-amplitude frequency-modulation atomic force microscopy and atomic contrast formation is now well understood. It has been shown that the apparent contrast patterns obtained…

Materials Science · Physics 2007-05-23 Franz J. Giessibl , Michael Reichling

This work presents an innovative magnetoelastic (ME) biosensor using graphene functionalized with the SARS-CoV-2 N protein for antibody detection via magnetoelastic resonance. Graphene was chosen for its biocompatibility and high surface…

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