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The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global medical systems and economies, and rules our daily living life. Controlling the outbreak of SARS-CoV-2 has become one of the most important…

Medical Physics · Physics 2020-10-09 Jing Zhong , Enja Laureen Roesch , Thilo Viereck , Meinhard Schilling , Frank Ludwig

The COVID-19 pandemic has profoundly impacted global economies and healthcare systems, revealing critical vulnerabilities in both. In response, our study introduces a groundbreaking method for the detection of SARS-CoV-2 cDNA, leveraging…

Rapid, sensitive detection of biomolecules is important for improved testing methods for viruses as well as biomarkers and environmental hormones. For example, testing for SARS-CoV-2 is essential in the fight against the COVID-19 pandemic.…

The pandemic of coronavirus disease 2019 (COVID-19) caused by syndrome-coronavirus-2 (SARS-CoV-2) has been found rapid and large-scale diagnosis to spread across the communities. The risk of infectious airborne aerosol transmission has been…

Biological Physics · Physics 2022-05-02 Hanzhi Yang

The development of highly sensitive and rapid biosensing tools targeted to the highly contagious virus SARS-CoV-2 is critical to tackling the COVID-19 pandemic. Quantum sensors can play an important role, thanks to their superior…

Quantum Physics · Physics 2022-01-25 Changhao Li , Rouhollah Soleyman , Mohammad Kohandel , Paola Cappellaro

Simple methods to detect biomolecules including specific nucleic acid sequences have received renewed attention since the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus pandemic. Notably, biomolecule detection that uses…

Biomolecules · Quantitative Biology 2024-09-09 A. A. Aldakheel , C. B. Raub , H. T. Bui

We propose a new optical biosensor based on a photonic crystal with a defect layer, which can determine the SARS-CoV-2 concentration in water by the defect mode shift. Two models of the dependence of the refractive index of the defect layer…

Instrumentation and Detectors · Physics 2022-04-27 I. M. Efimov , N. A. Vanyushkin , A. H. Gevorgyan , S. S. Golik

In the context of continued spread of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 and the emergence of new variants, the demand for rapid, accurate, and frequent detection is increasing. Besides, the new predominant strain,…

During the early stages of respiratory virus outbreaks, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the efficient utilize of limited nasopharyngeal swabs for rapid and accurate screening is crucial for public…

Signal Processing · Electrical Eng. & Systems 2024-10-29 Wenwen Zhang , Zhouzhuo Tang , Yingmei Feng , Xia Yu , Qi Jie Wang , Zhiping Lin

The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

This work presents a high-performance, multilayered surface plasmon resonance (SPR)-based sensor designed to enhance performance parameters in the near-infrared (NIR) region through angular interrogation. The multi-layered sensor consists…

Optics · Physics 2025-11-11 R. Runthala , N. Grover , P. Arora

Smokers being witnessed with the mild adverse clinical symptoms of SARS-CoV-2, the in-silico study is intended to explore the effect of nicotine binding to the soluble angiotensin converting enzyme II (ACE2) receptor with or without…

Biomolecules · Quantitative Biology 2020-05-01 Selvaa Kumar C , Senthil Arun Kumar , Haiyan Wei

COVID-19 has affected the world tremendously. It is critical that biological experiments and clinical designs are informed by computational approaches for time- and cost-effective solutions. Comparative analyses particularly can play a key…

Biomolecules · Quantitative Biology 2020-04-10 Goksel Misirli

The {\it{in vitro}} antiviral activity of Hydroxychloroquine (HCQ) and chloroquine (CQ) against SARS-CoV-2 from the first month of pandemic proposed these drugs as the appropriate therapeutic candidate, although their side effect directed…

Medical Physics · Physics 2021-01-26 Parham Rezaee , Mahmood Akbari , Razieh Morad , Amin Koochaki , Malik Maaz , Zahra Jamshidi

The study proposes a new efficient wireless biosensor based on magnetoelastic waves for the detection of antibodies in human plasma, aiming at the serological diagnosis of COVID-19. The biosensor was functionalized with the N antigen -…

The sudden rise of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic early 2020 throughout the world has called into drastic action measures to do instant detection and reduce the spread rate. The common diagnostics…

Instrumentation and Detectors · Physics 2024-06-12 Aref Asghari , Chao Wang , Kyoung Min Yoo , Hamed Dalir , Ray T. Chen

Optical fiber sensing carries a number of potential advantages for diagnostics and biomarker detection and monitoring, yet particular challenges persist in linking molecular recognition events to a change in the refractive index. DNA…

Effective and efficient management of human betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 infection i.e., COVID-19 pandemic, required sensitive sensors with short sample-to-result durations for performing diagnostics. In…

Under the global health emergency caused by coronavirus disease 2019 (COVID-19), efficient and specific therapies are urgently needed. Compared with traditional small-molecular drugs, antibody therapies are relatively easy to develop and as…

Biomolecules · Quantitative Biology 2020-06-19 Jiahui Chen , Kaifu Gao , Rui Wang , Duc Duy Nguyen , Guo-Wei Wei

With the ongoing global pandemic of coronavirus disease 2019 (COVID-19), there is an increasing quest for more accessible, easy-to-use, rapid, inexpensive, and high accuracy diagnostic tools. Traditional disease diagnostic methods such as…

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