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Modern high-throughput biomedical devices routinely produce data on a large scale, and the analysis of high-dimensional datasets has become commonplace in biomedical studies. However, given thousands or tens of thousands of measured…

Methodology · Statistics 2022-02-28 Vladimir Vutov , Thorsten Dickhaus

We propose a kernel-based partial permutation test for checking the equality of functional relationship between response and covariates among different groups. The main idea, which is intuitive and easy to implement, is to keep the…

Methodology · Statistics 2021-11-01 Xinran Li , Bo Jiang , Jun S. Liu

We develop the distribution of the number of hypotheses found to be statistically significant using the rule from Benjamini and Hochberg (1995) for controlling the false discovery rate (FDR). This distribution has both a small sample form…

Methodology · Statistics 2018-02-27 Chang Yu , Daniel Zelterman

In this paper, we present a new classifier, which integrates significance testing results over different random subspaces to yield consensus p-values for quantifying the uncertainty of classification decision. The null hypothesis is that…

Machine Learning · Computer Science 2024-10-17 Zengyou He , Zerun Li , Junjie Dong , Xinying Liu , Mudi Jiang , Lianyu Hu

Hypothesis testing of structure in covariance matrices is of significant importance, but faces great challenges in high-dimensional settings. Although consistent frequentist one-sample covariance tests have been proposed, there is a lack of…

Methodology · Statistics 2020-07-22 Kyoungjae Lee , Lizhen Lin , David Dunson

Multiple hypothesis testing problems arise naturally in science. In this paper, we introduce the new Fast Closed Testing (FACT) method for multiple testing, controlling the family-wise error rate. This error rate is state of the art in many…

Methodology · Statistics 2020-01-22 Edgar Dobriban

This research deals with massive multiple hypothesis testing. First regarding multiple tests as an estimation problem under a proper population model, an error measurement called Erroneous Rejection Ratio (ERR) is introduced and related to…

Statistics Theory · Mathematics 2007-06-13 Cheng Cheng

For a property $P$ and a sub-property $P'$, we say that $P$ is $P'$-partially testable with $q$ queries if there exists an algorithm that distinguishes, with high probability, inputs in $P'$ from inputs $\epsilon$-far from $P$ by using $q$…

Computational Complexity · Computer Science 2013-06-07 Eldar Fischer , Yonatan Goldhirsh , Oded Lachish

We consider the problem of testing positively dependent multiple hypotheses assuming that a prior information about the dependence structure is available. We propose two-step multiple comparisons procedures that exploit the prior…

Empirical economic studies often involve multiple propositions or hypotheses, with researchers aiming to assess both the collective and individual evidence against these propositions or hypotheses. To rigorously assess this evidence,…

Econometrics · Economics 2024-08-26 Zeng-Hua Lu

The p-value or statistical significance of a CP conservation null hypothesis test is determined from counting electron neutrino and antineutrino appearance oscillation events. The statistical estimates include cases with background events…

High Energy Physics - Experiment · Physics 2019-02-20 Walter Toki , Thomas W. Campbell , Erez Reinherz-Aronis

Positive predictive value and negative predictive value are two widely used parameters to assess the clinical usefulness of a medical diagnostic test. When there are two diagnostic tests, it is recommendable to make a comparative assessment…

Methodology · Statistics 2024-05-29 Antonio Martín Andrés , Pedro Femia Marzo

Missing data are often dealt with multiple imputation. A crucial part of the multiple imputation process is selecting sensible models to generate plausible values for incomplete data. A method based on posterior predictive checking is…

Computation · Statistics 2026-05-14 Mingyang Cai , Stef van Buuren , Gerko Vink

The closure principle is fundamental in multiple testing and has been used to derive many efficient procedures with familywise error rate control. However, it is often unsuitable for modern research, which involves flexible multiple testing…

Methodology · Statistics 2024-05-27 Lasse Fischer , Marta Bofill Roig , Werner Brannath

We consider the multiple hypothesis testing (MHT) problem over the joint domain formed by a graph and a measure space. On each sample point of this joint domain, we assign a hypothesis test and a corresponding $p$-value. The goal is to make…

Signal Processing · Electrical Eng. & Systems 2025-06-05 Xingchao Jian , Martin Gölz , Feng Ji , Wee Peng Tay , Abdelhak M. Zoubir

In a high dimensional regression setting in which the number of variables ($p$) is much larger than the sample size ($n$), the number of possible two-way interactions between the variables is immense. If the number of variables is in the…

Methodology · Statistics 2024-06-26 Marianne A Jonker , Luc van Schijndel , Eric Cator

This work investigates multiple testing by considering minimax separation rates in the sparse sequence model, when the testing risk is measured as the sum FDR+FNR (False Discovery Rate plus False Negative Rate). First using the popular…

Statistics Theory · Mathematics 2023-08-31 Kweku Abraham , Ismael Castillo , Etienne Roquain

We consider variable selection in high-dimensional linear models where the number of covariates greatly exceeds the sample size. We introduce the new concept of partial faithfulness and use it to infer associations between the covariates…

Methodology · Statistics 2012-01-12 Peter Bühlmann , Markus Kalisch , Marloes H. Maathuis

In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…

Other Quantitative Biology · Quantitative Biology 2020-03-31 Tarun Jain , Bijendra Nath Jain

Given a multiple testing situation, the null hypotheses that appear to have sufficiently low probabilities of truth may be rejected using a simple, nonparametric method of decision theory. This applies not only to posterior levels of…

Probability · Mathematics 2025-10-20 David R. Bickel
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