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In the present paper, a new three-scale asymptotic homogenization method is proposed to study the electrical behavior of the cardiac tissue structure with multiple heterogeneities at two different levels. The first level is associated with…

Analysis of PDEs · Mathematics 2022-01-11 Fakhrielddine Bader , Mostafa Bendahmane , Mazen Saad , Raafat Talhouk

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

Numerical Analysis · Mathematics 2022-08-12 Michele Bucelli , Alberto Zingaro , Pasquale Claudio Africa , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Combining physics-based modeling with data-driven methods is critical to enabling the translation of computational methods to clinical use in cardiology. The use of rigorous differential equations combined with machine learning tools allows…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Elena Martinez , Beatrice Moscoloni , Matteo Salvador , Fanwei Kong , Mathias Peirlinck , Alison Lesley Marsden

We study the homogenization of a novel microscopic tridomain system, allowing for a more detailed analysis of the properties of cardiac conduction than the classical bidomain and monodomain models. In (Acta Appl.Math. 179 (2022) 1--35), we…

Analysis of PDEs · Mathematics 2022-09-16 Fakhrielddine Bader , Mostafa Bendahmane , Mazen Saad , Raafat Talhouk

Myocardial motion tracking stands as an essential clinical tool in the prevention and detection of cardiovascular diseases (CVDs), the foremost cause of death globally. However, current techniques suffer from incomplete and inaccurate…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Chengkang Shen , Hao Zhu , You Zhou , Yu Liu , Si Yi , Lili Dong , Weipeng Zhao , David J. Brady , Xun Cao , Zhan Ma , Yi Lin

In numerical simulations of cardiac mechanics, coupling the heart to a model of the circulatory system is essential for capturing physiological cardiac behavior. A popular and efficient technique is to use an electrical circuit analogy,…

The numerical tools to simulate the bidomain model in cardiac electrophysiology are constantly developing due to the great clinical interest and scientific advances in mathematical models and computational power. The bidomain model consists…

Numerical Analysis · Mathematics 2025-11-03 Gopika P B , Peter Bastian , Nagaiah Chamakuri

Conditional video diffusion models (CDM) have shown promising results for video synthesis, potentially enabling the generation of realistic echocardiograms to address the problem of data scarcity. However, current CDMs require a paired…

Image and Video Processing · Electrical Eng. & Systems 2024-09-09 Van Phi Nguyen , Tri Nhan Luong Ha , Huy Hieu Pham , Quoc Long Tran

In this paper, we present a novel Image Fusion Model (IFM) for ECG heart-beat classification to overcome the weaknesses of existing machine learning techniques that rely either on manual feature extraction or direct utilization of 1D raw…

Signal Processing · Electrical Eng. & Systems 2021-05-31 Zeeshan Ahmad , Anika Tabassum , Naimul Khan , Ling Guan

Early detection of cardiac dysfunction through routine screening is vital for diagnosing cardiovascular diseases. An important metric of cardiac function is the left ventricular ejection fraction (EF), where lower EF is associated with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Ece Ozkan , Thomas M. Sutter , Yurong Hu , Sebastian Balzer , Julia E. Vogt

In this paper, we consider the monodomain model of cardiac electrophysiology. After an analysis of the well-posedness of the forward problem, we show that perfectly insulating regions (modeling ischemic regions in the cardiac tissue) can be…

Analysis of PDEs · Mathematics 2024-07-15 Andrea Aspri , Elena Beretta , Elisa Francini , Dario Pierotti , Sergio Vessella

Electrocardiogram (ECG) is an authoritative source to diagnose and counter critical cardiovascular syndromes such as arrhythmia and myocardial infarction (MI). Current machine learning techniques either depend on manually extracted features…

Machine Learning · Computer Science 2021-07-22 Zeeshan Ahmad , Anika Tabassum , Ling Guan , Naimul Khan

In this paper we consider the monodomain model of cardiac electrophysiology. After an analysis of the well-posedness of the model, we determine an asymptotic expansion of the perturbed potential due to the presence of small conductivity…

Analysis of PDEs · Mathematics 2020-10-28 Elena Beretta , Cecilia Cavaterra , Luca Ratti

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

The electrocardiogram (ECG) has always been an important biomedical test to diagnose cardiovascular diseases. Current approaches for ECG monitoring are based on body attached electrodes leading to uncomfortable user experience. Therefore,…

Signal Processing · Electrical Eng. & Systems 2022-11-22 Jinbo Chen , Dongheng Zhang , Zhi Wu , Fang Zhou , Qibin Sun , Yan Chen

Electrocardiogram (ECG) signals, profiling the electrical activities of the heart, are used for a plethora of diagnostic applications. However, ECG systems require multiple leads or channels of signals to capture the complete view of the…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Nabil Ibtehaz , Masood Mortazavi

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

Myocardial contrast echocardiography (MCE) is an imaging technique that assesses left ventricle function and myocardial perfusion for the detection of coronary artery diseases. Automatic MCE perfusion quantification is challenging and…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Yuanwei Li , Chin Pang Ho , Matthieu Toulemonde , Navtej Chahal , Roxy Senior , Meng-Xing Tang

Fully explicit stabilized multirate (mRKC) methods are well-suited for the numerical solution of large multiscale systems of stiff ordinary differential equations thanks to their improved stability properties. To demonstrate their…

Numerical Analysis · Mathematics 2024-06-25 Giacomo Rosilho de Souza , Marcus J. Grote , Simone Pezzuto , Rolf Krause

Calcification has significant influence over cardiovascular diseases and interventions. Detailed characterization of calcification is thus desired for predictive modeling, but calcified heart meshes for physics-driven simulations are still…

Computational Engineering, Finance, and Science · Computer Science 2024-03-11 Daniel H. Pak , Minliang Liu , Theodore Kim , Caglar Ozturk , Raymond McKay , Ellen T. Roche , Rudolph Gleason , James S. Duncan