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Ptychography, as a powerful lensless imaging method, has become a popular member of the coherent diffractive imaging family over decades of development. The ability to utilize low-dose X-rays and/or fast scans offers a big advantage in a…

Medical Physics · Physics 2024-06-14 Longlong Wu , Shinjae Yoo , Yong S. Chu , Xiaojing Huang , Ian K. Robinson

Phase-contrast microscopy converts the optical phase introduced by transparent, unlabeled specimens into modulation in the intensity image. Modern phase imaging techniques are capable of quantifying phase shift at each point in the field of…

Contrast-enhanced computed tomography (CT) imaging is essential for diagnosing and monitoring thoracic diseases, including aortic pathologies. However, contrast agents pose risks such as nephrotoxicity and allergic-like reactions. The…

Image and Video Processing · Electrical Eng. & Systems 2025-09-08 Pouya Shiri , Xin Yi , Neel P. Mistry , Samaneh Javadinia , Mohammad Chegini , Seok-Bum Ko , Amirali Baniasadi , Scott J. Adams

In this paper we tackle the problem of recovering the phase of complex linear measurements when only magnitude information is available and we control the input. We are motivated by the recent development of dedicated optics-based hardware…

Machine Learning · Computer Science 2020-02-17 Sidharth Gupta , Rémi Gribonval , Laurent Daudet , Ivan Dokmanić

Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA.…

Methodology · Statistics 2018-07-11 Stefan Engblom , Carl Nettelblad , Jing Liu

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

Electron backscatter diffraction (EBSD) has developed over the last few decades into a valuable crystallographic characterisation method for a wide range of sample types. Despite these advances, issues such as the complexity of sample…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Zoë Broad , Alex W. Robinson , Jack Wells , Daniel Nicholls , Amirafshar Moshtaghpour , Angus I. Kirkland , Nigel D. Browning

Spectroscopic ptychography is a powerful technique to determine the chemical composition of a sample with high spatial resolution. In spectro-ptychography, a sample is rastered through a focused x-ray beam with varying photon energy so that…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Huibin Chang , Ziqin Rong , Pablo Enfedaque , Stefano Marchesini

A unified method for three-dimensional reconstruction of objects from transmission images collected at multiple illumination directions is described. The method may be applicable to experimental conditions relevant to absorption-based,…

Medical Physics · Physics 2022-12-07 Timur E. Gureyev , Hamish G. Brown , Harry M. Quiney , Leslie J. Allen

The displacement field in highly non uniformly strained crystals is obtained by addition of constraints to an iterative phase retrieval algorithm. These constraints include direct space density uniformity and also constraints to the sign…

Materials Science · Physics 2009-11-11 A. A. Minkevich , M. Gailhanou , J. -S. Micha , B. Charlet , V. Chamard , O. Thomas

Quantitative differential phase contrast imaging of materials in atomic-resolution scanning transmission electron microscopy using segmented detectors is limited by various factors, including coherent and incoherent aberrations, detector…

Early detection through imaging and accurate diagnosis is crucial in mitigating the high mortality rate associated with breast cancer. However, locating tumors from low-resolution and high-noise medical images is extremely challenging.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Feiyan Feng , Tianyu Liu , Hong Wang , Jun Zhao , Wei Li , Yanshen Sun

While in situ experiments are gaining importance for the (mechanical) assessment of metamaterials or materials with complex microstructures, imaging conditions in such experiments are often challenging. The lab-based computed tomography…

A key contribution to X-ray dark-field (XDF) is X-ray diffusion by sample structures smaller than the imaging system's spatial resolution. However, some XDF techniques report that resolvable sample edges also generate XDF. Speckle-based…

We describe a phase-retrieval-based imaging method to directly spatially resolve the vector lattice distortions in an extended crystalline sample by explicit coupling of independent Bragg ptychography data sets into the reconstruction…

In conventional x-ray ptychography, diffraction data is collected by scanning a sample through a monochromatic, and spatially coherent, x-ray beam. A high-resolution image is then retrieved using an iterative algorithm. Combined with a scan…

Optics · Physics 2025-08-26 Wiebe Stolp , Silvia Cipiccia , Darren Batey , Matthieu Boone

Differential phase-contrast computed tomography (DPC-CT) is a powerful analysis tool for soft-tissue and low-atomic-number samples. Limited by the implementation conditions, DPC-CT with incomplete projections happens quite often.…

Medical Physics · Physics 2020-07-01 Jianbing Dong , Jian Fu , Zhao He

X-ray tomography is capable of imaging the interior of objects in three dimensions non-invasively, with applications in biomedical imaging, materials science, electronic inspection, and other fields. The reconstruction process can be an…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Zhen Guo , Jung Ki Song , George Barbastathis , Michael E. Glinsky , Courtenay T. Vaughan , Kurt W. Larson , Bradley K. Alpert , Zachary H. Levine

For grating-based x-ray phase contrast imaging (GPCI), a multi-order moment analysis (MMA) has been recently developed to obtain multiple contrasts from the ultra-small-angle x-ray scattering distribution, as a novel information retrieval…

Medical Physics · Physics 2020-01-01 Chengpeng Wu , Li Zhang , Xinbin Li , Zhiqiang Chen , Yuxiang Xing , Xiaohua Zhu , Hewei Gao

Since the invention of Zernike phase contrast method in 1930, it has been widely used in optical microscopy and more recently in X-ray microscopy. Considering the image contrast is a mixture of absorption and phase information, we recently…

Optics · Physics 2015-12-03 Heng Chen , Kun Gao , Dajiang Wang , Li Song , Zhili Wang