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Paganin's method for image reconstruction in propagation-based phase-contrast X-ray imaging and tomography has enjoyed broad acceptance in recent years, with over one thousand publications citing its use. The present paper discusses…

Medical Physics · Physics 2026-01-13 Timur E. Gureyev , David M. Paganin , Ashkan Pakzad , Harry M. Quiney

X-ray phase contrast tomography (XPCT) is widely used for 3D imaging of objects with weak contrast in X-ray absorption index but strong contrast in refractive index decrement. To reconstruct an object imaged using XPCT, phase retrieval…

Image and Video Processing · Electrical Eng. & Systems 2020-09-23 K. Aditya Mohan , Dilworth Y. Parkinson , Jefferson A. Cuadra

Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

The evolution of synchrotrons towards higher brilliance beams has increased the possible sample-to-detector propagation distances for which the source confusion circle does not lead to geometrical blurring. This makes it possible to push…

Coherent X-ray beams with energies $\geq 50$ keV can potentially enable three-dimensional imaging of atomic lattice distortion fields within individual crystallites in bulk polycrystalline materials through Bragg coherent diffraction…

Propagation-based neutron phase-contrast tomography was demonstrated using the ISIS pulsed spallation source. The proof-of-concept tomogram with Paganin-type phase-retrieval filter applied exhibited an effective net boost of $23\pm 1$ in…

Image and Video Processing · Electrical Eng. & Systems 2023-07-31 David M. Paganin , Morten Sales , Peter M. Kadletz , Winfried Kockelmann , Mario A. Beltran , Henning F. Poulsen , Søren Schmidt

X-ray phase-contrast imaging (XPCI) is a versatile technique with wide-ranging applications, particularly in the fields of biology and medicine. Where X-ray absorption radiography requires high density ratios for effective imaging, XPCI is…

We propose a one-shot thickness measurement method for sponge-like structures using a propagation-based X-ray phase-contrast imaging (P-PCI) method. In P-PCI, the air-material interface refracts the incident X-ray. Refracted many times…

Medical Physics · Physics 2015-04-27 Yan Xi , Rongbiao Tang , Jingchen Ma , Jun Zhao

Ptychography is an attractive advance of coherent diffraction imaging (CDI), which can provide high lateral resolution and wide field of view. The theoretical resolution of ptychography is dose-limited, therefore making ptychography…

Biological Physics · Physics 2025-01-09 Huixiang Lin , Fucai Zhang

Dark-field X-ray imaging is a novel modality which visualises scattering from unresolved microstructure. Most dark-field imaging techniques rely on crystals or structured illumination, but recent work has shown that dark-field effects are…

Medical Physics · Physics 2024-09-04 Jannis N. Ahlers , Konstantin M. Pavlov , Marcus J. Kitchen , Kaye S. Morgan

X-ray imaging, traditionally relying on attenuation contrast, struggles to differentiate materials with similar attenuation coefficients like soft tissues. X-ray phase contrast imaging (XPCI) and dark-field (DF) imaging provide enhanced…

Medical Physics · Physics 2025-06-05 Jingcheng Yuan , Mini Das

These tutorials introduce some basics of imaging with coherent X-rays, focusing on phase contrast. We consider the transport-of-intensity equation, as one particular method for X-ray phase contrast imaging among many, before passing on to…

Image and Video Processing · Electrical Eng. & Systems 2019-02-28 David M. Paganin , Daniele Pelliccia

Coherent diffractive imaging (CDI) provides new opportunities for high resolution X-ray imaging with simultaneous amplitude and phase contrast. Extensions to CDI broaden the scope of the technique for use in a wide variety of experimental…

Optics · Physics 2016-01-20 Matthew H. Seaberg , Alexandre d'Aspremont , Joshua J. Turner

Imaging with hard x-rays is an invaluable tool in medicine, biology, materials science, and cultural heritage. Propagation-based x-ray phase-contrast imaging and tomography have been mostly used to resolve micrometer-scale structures inside…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Margie P. Olbinado , David M. Paganin , Yin Cheng , Alexander Rack

Direct ptychography enables the retrieval of information encoded in the phase of an electron wave passing through a thin sample by deconvolving the interference effects of a converged probe with known aberrations. Under the weak phase…

The problem of optimization of propagation-based phase-contrast imaging setups is considered in the case of projection X-ray imaging and three-dimensional tomography with phase retrieval. For two-dimensional imaging, a simple model for a…

Medical Physics · Physics 2026-03-03 T. E. Gureyev , D. M. Paganin , H. M. Quiney

Holographic coherent X-ray imaging enables nanoscale imaging of biological cells and tissues, rendering both phase and absorption contrast, i.e. real and imaginary parts of the refractive index. Unlike the standard model, which assumes a…

Analysis of PDEs · Mathematics 2026-05-29 Thorsten Hohage , Milad Karimi , Björn Müller

X-Ray Phase-Contrast Imaging (PCI) yields absorption, differential phase, and dark-field images. Computed Tomography (CT) of grating-based PCI can in principle provide high-resolution soft-tissue contrast. Recently, grating-based PCI took…

Detection of phase variations across optically transparent samples is often a difficult task. We propose and demonstrate a compact, lightweight and low cost quantitative phase contrast imager. Light diffracted from a pinhole is incident on…

X-ray phase contrast imaging holds great promise for improving the visibility of light-element materials such as soft tissues and tumors. Single-mask differential phase contrastnimaging method stands out as a simple and effective approach…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jingcheng Yuan , Mini Das