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Generative approaches for cross-modality transformation have recently gained significant attention in neuroimaging. While most previous work has focused on case-control data, the application of generative models to disorder-specific…

Neurons and Cognition · Quantitative Biology 2024-05-10 Reihaneh Hassanzadeh , Anees Abrol , Hamid Reza Hassanzadeh , Vince D. Calhoun

The diagnosis of early stages of Alzheimer's disease (AD) is essential for timely treatment to slow further deterioration. Visualizing the morphological features for the early stages of AD is of great clinical value. In this work, a novel…

Image and Video Processing · Electrical Eng. & Systems 2021-11-29 Wen Yu , Baiying Lei , Yanyan Shen , Shuqiang Wang , Yong Liu , Zhiguang Feng , Yong Hu , Michael K. Ng

Frontotemporal dementia and Alzheimer's disease are two common forms of dementia and are easily misdiagnosed as each other due to their similar pattern of clinical symptoms. Differentiating between the two dementia types is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Da Ma , Donghuan Lu , Karteek Popuri , Mirza Faisal Beg

Alzheimer's disease (AD) affects 50 million people worldwide and is projected to overwhelm 152 million by 2050. AD is characterized by cognitive decline due partly to disruptions in metabolic brain connectivity. Thus, early and accurate…

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Lilia Lazli

In this paper, a dynamic dual-graph fusion convolutional network is proposed to improve Alzheimer's disease (AD) diagnosis performance. The following are the paper's main contributions: (a) propose a novel dynamic GCN architecture, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Fanshi Li , Zhihui Wang , Yifan Guo , Congcong Liu , Yanjie Zhu , Yihang Zhou , Jun Li , Dong Liang , Haifeng Wang

In this paper, we present a memory-augmented algorithm for anomaly detection. Classical anomaly detection algorithms focus on learning to model and generate normal data, but typically guarantees for detecting anomalous data are weak. The…

Machine Learning · Computer Science 2020-02-10 Ziyi Yang , Teng Zhang , Iman Soltani Bozchalooi , Eric Darve

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…

Machine Learning · Computer Science 2025-04-03 Jing Wang , Jun-En Ding , Feng Liu , Elisa Kallioniemi , Shuqiang Wang , Wen-Xiang Tsai , Albert C. Yang

Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's…

Computer Vision and Pattern Recognition · Computer Science 2017-12-21 Jyoti Islam , Yanqing Zhang

Graph theoretical methods have proven valuable for investigating alterations in both anatomical and functional brain connectivity networks during Alzheimer's disease (AD). Recent studies suggest that representing brain networks in a…

Neurons and Cognition · Quantitative Biology 2025-04-04 Alice Longhena , Martin Guillemaud , Fabrizio De Vico Fallani , Raffaella Lara Migliaccio , Mario Chavez

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

Emerging evidence shows that cognitive deficits in Alzheimer disease (AD) are associated with disruptions in brain functional connectivity. Thus, the identification of alterations in AD functional networks has become a topic of increasing…

Neurons and Cognition · Quantitative Biology 2018-02-27 A. Kabbara , H. Eid , EL W. Falou , M. Khalil , F. Wendling , M. Hassan

Electrocardiogram (ECG) acquisition requires an automated system and analysis pipeline for understanding specific rhythm irregularities. Deep neural networks have become a popular technique for tracing ECG signals, outperforming human…

Alzheimer's Disease (AD) is a non-curable progressive neurodegenerative disorder that affects the human brain, leading to a decline in memory, cognitive abilities, and eventually, the ability to carry out daily tasks. Manual diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Santanu Roy , Archit Gupta , Shubhi Tiwari , Palak Sahu

Deep graph learning has advanced Alzheimer's (AD) disease classification from MRI, but most models remain correlational, confounding demographic and genetic factors with disease specific features. We present Causal-GCN, an interventional…

Machine Learning · Computer Science 2025-11-20 Pranay Kumar Peddi , Dhrubajyoti Ghosh

Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the…

Machine Learning · Computer Science 2022-04-29 Houliang Zhou , Lifang He , Yu Zhang , Li Shen , Brian Chen

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima

Positron Emission Tomography (PET) is now regarded as the gold standard for the diagnosis of Alzheimer's Disease (AD). However, PET imaging can be prohibitive in terms of cost and planning, and is also among the imaging techniques with the…

Alzheimer's Disease (AD) is the most widespread neurodegenerative disease, affecting over 50 million people across the world. While its progression cannot be stopped, early and accurate diagnostic testing can drastically improve quality of…

Machine Learning · Computer Science 2021-01-11 Vishnu Ram Sampathkumar

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg