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We report that population dynamics in fluctuating environment accompanies mathematically equivalent structure to steady state thermodynamics. By employing the structure, population growth in fluctuating environment is decomposed into…

Statistical Mechanics · Physics 2016-03-04 Yuki Sughiyama , Tetsuya J. Kobayashi

In this paper, we use the cell dynamics method to study the dynamics of phase transformation when three phases exist. The system we study is a two-dimensional system. The system is able to achieve three phases coexistence, which for…

Materials Science · Physics 2009-11-11 M. Iwamatsu

We study a moving boundary problem describing the growth of nonnecrotic tumors in different regimes of vascularisation. This model consists of two decoupled Dirichlet problem, one for the rate at which nutrient is added to the tumor domain…

Analysis of PDEs · Mathematics 2010-03-05 Joachim Escher , Anca-Voichita Matioc

Translation of proteins is a fundamental part of gene expression that is mediated by ribosomes. As ribosomes significantly contribute to both cellular mass and energy consumption, achieving efficient management of the ribosome population is…

Subcellular Processes · Quantitative Biology 2024-04-18 Clément Soubrier , Eric Foxall , Luca Ciandrini , Khanh Dao Duc

A dynamical version of the Widom-Rowlinsom model in the continuum is considered. The dynamics is modelled by a spatial two-component birth-and-death Glauber process where particles, in addition, are allowed to change their type with density…

Dynamical Systems · Mathematics 2022-03-17 Martin Friesen

Phase separation has emerged as an essential concept for the spatial organization inside biological cells. However, despite the clear relevance to virtually all physiological functions, we understand surprisingly little about what phases…

Biological Physics · Physics 2022-08-10 David Zwicker , Liedewij Laan

We investigate the variational model for nematic elastomer proposed by Barchiesi and DeSimone with the director field defined on the deformed configuration under general growth conditions on the elastic density. This leads us to consider…

Analysis of PDEs · Mathematics 2025-07-22 Marco Bresciani , Bianca Stroffolini

Plant morphogenesis relies on dynamic growth deformations at the cell and tissue scales driven by osmotic fluxes. A mechanistic understanding of this phenomenon demands a physical framework that integrates cell imbibition, tissue mechanics,…

Biological Physics · Physics 2025-12-08 Hadrien Oliveri , Christophe Godin , Ibrahim Cheddadi

We consider a differential quasivariational inequality for which we state and prove the continuous dependence of the solution with respect to the data. This convergence result allows us to prove the existence of at least one optimal pair…

Analysis of PDEs · Mathematics 2020-09-10 Mircea Sofonea , Julieta Bollati , Domingo A. Tarzia

The work analyzes a one-dimensional viscoelastic model of blood vessel growth under nonlinear friction with surroundings, and provides numerical simulations for various growing cases. For the nonlinear differential equations, two sufficient…

Analysis of PDEs · Mathematics 2010-10-18 Chunjing Xie , Xiaoming Zheng

We extend the notions of multipole and subsystem symmetries to more general {\it spatially modulated} symmetries. We uncover two instances with exponential and (quasi)-periodic modulations, and provide simple microscopic models in one, two…

Statistical Mechanics · Physics 2021-10-19 Pablo Sala , Julius Lehmann , Tibor Rakovszky , Frank Pollmann

In this manuscript, we study a nonlinear model of tumor growth, described by a coupled hyperbolic-elliptic system of partial differential equations. In this model, the compressible flow of tumor cells is modeled by a transport equation for…

Analysis of PDEs · Mathematics 2025-08-27 Jeffrey Kuan , Konstantina Trivisa

Robust control of complex engineered and biological systems hinges on the integration of feedforward and feedback mechanisms. This is exemplified in neural motor control, where feedforward muscle co-contraction complements sensory-driven…

Optimization and Control · Mathematics 2026-03-06 Bastien Berret , Frédéric Jean

A class of evolution quasistatic systems which leads, after a suitable time discretization, to recursive nonlinear programs, is considered and optimal control or identification problems governed by such systems are investigated. The…

Optimization and Control · Mathematics 2014-11-19 L. Adam , J. V. Outrata , T. Roubicek

Conserved growth models that exhibit a nonlinear instability in which the height (depth) of isolated pillars (grooves) grows in time are studied by numerical integration and stochastic simulation. When this instability is controlled by the…

Statistical Mechanics · Physics 2009-11-07 B. Chakrabarti , C. Dasgupta

Morphogenesis, the process of growth and shape formation in biological tissues, is driven by complex interactions between mechanical, biochemical, and genetic factors. Traditional models of biological growth often rely on the concept of…

Biological Physics · Physics 2025-05-05 Alexander Erlich , Giuseppe Zurlo

We analyse the asymptotic behaviour of a nonlinear mathematical model of cellular proliferation which describes the production of blood cells in the bone marrow. This model takes the form of a system of two maturity structured partial…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Laurent Pujo-Menjouet

In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…

Analysis of PDEs · Mathematics 2022-05-25 Slah Eddin Ben Abdeljalil , Atef Ben Essid , Saloua Mani Aouadi

We study a mathematical model describing the growth process of a population structured by age and a phenotypical trait, subject to aging, competition between individuals and rare mutations. Our goals are to describe the asymptotic behaviour…

Analysis of PDEs · Mathematics 2020-04-17 Samuel Nordmann , Benoît Perthame , Cécile Taing

Growth-elasticity is a powerful model framework for understanding complex shape development in soft biological tissues. At each instant, by mapping how continuum building blocks have grown geometrically and how they respond elastically to…

Numerical Analysis · Mathematics 2024-10-23 Min Wu