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Deep generative models (DGMs) are data-eager because learning a complex model on limited data suffers from a large variance and easily overfits. Inspired by the classical perspective of the bias-variance tradeoff, we propose regularized…
This paper introduces a new generative deep learning network for human motion synthesis and control. Our key idea is to combine recurrent neural networks (RNNs) and adversarial training for human motion modeling. We first describe an…
Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…
In this work, we present a quantum circuit model for inferring gene regulatory networks (GRNs). The model is based on the idea of using qubit-qubit entanglement to simulate interactions between genes. We provide preliminary results that…
Deep learning has led to state-of-the-art results for many medical imaging tasks, such as segmentation of different anatomical structures. With the increased numbers of deep learning publications and openly available code, the approach to…
With different genomes available, unsupervised learning algorithms are essential in learning genome-wide biological insights. Especially, the functional characterization of different genomes is essential for us to understand lives. In this…
Research in developing data-driven models for Air Traffic Management (ATM) has gained a tremendous interest in recent years. However, data-driven models are known to have long training time and require large datasets to achieve good…
Gene Regulatory Network (GRN) inference is essential for understanding complex cellular mechanisms, rendered tractable through single-cell transcriptomic data. With the emergence of single-cell Foundation Models (scFMs), enhanced…
Designing accurate deep learning models for molecular property prediction plays an increasingly essential role in drug and material discovery. Recently, due to the scarcity of labeled molecules, self-supervised learning methods for learning…
Cell identity encompasses various semantic aspects of a cell, including cell type, pathway information, disease information, and more, which are essential for biologists to gain insights into its biological characteristics. Understanding…
Discovering gene-disease associations is crucial for understanding disease mechanisms, yet identifying these associations remains challenging due to the time and cost of biological experiments. Computational methods are increasingly vital…
Leveraging human perception into training of convolutional neural networks (CNN) has boosted generalization capabilities of such models in open-set recognition tasks. One of the active research questions is where (in the model architecture…
When modeling class-imbalanced data, it is crucial to address the imbalance, as models trained on such data tend to be biased towards the majority classes. This problem is amplified under partial supervision, where pseudo-labels for…
Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…
Decision-making is a dynamic process requiring perception, memory, and reasoning to make choices and find optimal policies. Traditional approaches to decision-making suffer from sample efficiency and generalization, while large-scale…
The introduction of the Transformer neural network, along with techniques like self-supervised pre-training and transfer learning, has paved the way for advanced models like BERT. Despite BERT's impressive performance, opportunities for…
We consider the task of detecting regulatory elements in the human genome directly from raw DNA. Past work has focused on small snippets of DNA, making it difficult to model long-distance dependencies that arise from DNA's 3-dimensional…
User modeling is critical for personalized web applications. Existing user modeling methods usually train user models from user behaviors with task-specific labeled data. However, labeled data in a target task may be insufficient for…
In the realm of recommendation systems, users exhibit a diverse array of behaviors when interacting with items. This phenomenon has spurred research into learning the implicit semantic relationships between these behaviors to enhance…
In this paper, we consider the supervised pre-trained transformer for a class of sequential decision-making problems. The class of considered problems is a subset of the general formulation of reinforcement learning in that there is no…