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We consider multi-class classification where the predictor has a hierarchical structure that allows for a very large number of labels both at train and test time. The predictive power of such models can heavily depend on the structure of…

Machine Learning · Statistics 2017-03-06 Yacine Jernite , Anna Choromanska , David Sontag

In this paper, we present contemporary techniques for visualising the feature space of a deep learning image classification neural network. These techniques are viewed in the context of a feed-forward network trained to classify low…

Computer Vision and Pattern Recognition · Computer Science 2018-11-16 Ezra Webb , Cheng Lei , Chun-Jung Huang , Hirofumi Kobayashi , Hideharu Mikami , Keisuke Goda

In this paper, we propose an efficient clustering technique to solve the problem of clustering in the presence of obstacles. The proposed algorithm divides the spatial area into rectangular cells. Each cell is associated with statistical…

Databases · Computer Science 2009-09-25 Mohamed E. El-Sharkawi , Mohamed A. El-Zawawy

Multiple instance learning is an ideal mode of analysis for histopathology data, where vast whole slide images are typically annotated with a single global label. In such cases, a whole slide image is modelled as a collection of tissue…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Leo Fillioux , Joseph Boyd , Maria Vakalopoulou , Paul-Henry Cournède , Stergios Christodoulidis

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…

Quantitative Methods · Quantitative Biology 2025-12-11 Noor Ul Huda Shah , Tanveer Hussain , Amr Ahmed , Yonghuai Liu , Usman Ali , Ardhendu Behera

Deep clustering which adopts deep neural networks to obtain optimal representations for clustering has been widely studied recently. In this paper, we propose a novel deep image clustering framework to learn a category-style latent…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Junjie Zhao , Donghuan Lu , Kai Ma , Yu Zhang , Yefeng Zheng

Automatic detection and segmentation of cells and nuclei in microscopy images is important for many biological applications. Recent successful learning-based approaches include per-pixel cell segmentation with subsequent pixel grouping, or…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Uwe Schmidt , Martin Weigert , Coleman Broaddus , Gene Myers

Existing self-supervised learning (SSL) methods primarily learn object-invariant representations but often neglect the spatial structure and relationships among object parts. To address this limitation, we introduce Spatial Prediction (SP),…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yang Shen , Yusen Cai , Weronika Hryniewska-Guzik , Qing Lin , Mengmi Zhang

Spatial transcriptomics has the potential to transform our understanding of RNA expression in tissues. Classical array-based technologies produce multiple-cell-scale measurements requiring deconvolution to recover single cell information.…

Endoscopy is a valuable tool for the early diagnosis of colon cancer. However, it requires the expertise of endoscopists and is a time-consuming process. In this work, we propose a new multi-label classification method, which considers two…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Zahra Sobhaninia , Nasrin Abharian , Nader Karimi , Shahram Shirani , Shadrokh Samavi

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Rushabh Patel

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Mo Zhang , Quanzheng Li

Analyzing and inspecting bone marrow cell cytomorphology is a critical but highly complex and time-consuming component of hematopathology diagnosis. Recent advancements in artificial intelligence have paved the way for the application of…

Computer Vision and Pattern Recognition · Computer Science 2022-05-23 Shayan Fazeli , Alireza Samiei , Thomas D. Lee , Majid Sarrafzadeh

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

Histopathological images of tumors contain abundant information about how tumors grow and how they interact with their micro-environment. Better understanding of tissue phenotypes in these images could reveal novel determinants of…

Image and Video Processing · Electrical Eng. & Systems 2021-04-14 Adalberto Claudio Quiros , Roderick Murray-Smith , Ke Yuan

Medical images differ from natural images in significantly higher resolutions and smaller regions of interest. Because of these differences, neural network architectures that work well for natural images might not be applicable to medical…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Yiqiu Shen , Nan Wu , Jason Phang , Jungkyu Park , Kangning Liu , Sudarshini Tyagi , Laura Heacock , S. Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

Place recognition gives a SLAM system the ability to correct cumulative errors. Unlike images that contain rich texture features, point clouds are almost pure geometric information which makes place recognition based on point clouds…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Lin Li , Xin Kong , Xiangrui Zhao , Tianxin Huang , Yong Liu