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Multilayer networks preserve full information about the different interactions among the constituents of a complex system, and have recently proven quite useful in modelling transportation networks, social circles, and the human brain. A…

Physics and Society · Physics 2020-06-29 Andrea Santoro , Vincenzo Nicosia

Leveraging hypergraph structures to model advanced processes has gained much attention over the last few years in many areas, ranging from protein-interaction in computational biology to image retrieval using machine learning. Hypergraph…

Human-Computer Interaction · Computer Science 2021-12-07 Maximilian T. Fischer , Alexander Frings , Daniel A. Keim , Daniel Seebacher

The introduction of network science approaches into public transport research has seen great advances in the past 15 years. However, it has become apparent that monolayer networks are often not sufficient to model and analyse real-world…

Physics and Society · Physics 2026-03-24 Tina Šfiligoj , Renzo Massobrio , Oded Cats

Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…

This article is addressing a recurrent problem in biology: mining newly built large scale networks. Our approach consists in comparing these new networks to well known ones. The visual backbone of this comparative analysis is provided by a…

Quantitative Methods · Quantitative Biology 2008-12-05 Romain Bourqui , Fabien Jourdan

Task taxonomies for graph and network visualizations focus on tasks commonly encountered when analyzing graph connectivity and topology. However, in many application fields such as the social sciences (social networks), biology (protein…

Human-Computer Interaction · Computer Science 2014-03-31 Bahador Saket , Paolo Simonetto , Stephen Kobourov

Understanding the origins of complexity is a fundamental challenge with implications for biological and technological systems. Network theory emerges as a powerful tool to model complex systems. Networks are an intuitive framework to…

Disordered Systems and Neural Networks · Physics 2024-10-22 Blai Vidiella , Salva Duran-Nebreda , Sergi Valverde

The study of networks plays a crucial role in investigating the structure, dynamics, and function of a wide variety of complex systems in myriad disciplines. Despite the success of traditional network analysis, standard networks provide a…

Physics and Society · Physics 2017-04-05 Manlio De Domenico , Clara Granell , Mason A. Porter , Alex Arenas

In the past years, network theory has successfully characterized the interaction among the constituents of a variety of complex systems, ranging from biological to technological, and social systems. However, up until recently, attention was…

Finding inherent or processed links within a dataset allows to discover potential knowledge. The main contribution of this article is to define a global framework that enables optimal knowledge discovery by visually rendering co-occurences…

Social and Information Networks · Computer Science 2018-09-05 Xavier Ouvrard , Jean-Marie Le Goff , Stephane Marchand-Maillet

Many complex networks are only a part of larger systems, where a number of coexisting topologies interact and depend on each other. We introduce a layered model to facilitate the description and analysis of such systems. As an example of…

Physics and Society · Physics 2007-05-23 Maciej Kurant , Patrick Thiran

In this paper, we present a survey of the use of graph theoretical techniques in Biology. In particular, we discuss recent work on identifying and modelling the structure of bio-molecular networks, as well as the application of centrality…

Molecular Networks · Quantitative Biology 2007-05-23 Oliver Mason , Mark Verwoerd

Empirical studies of graphs have contributed enormously to our understanding of complex systems. Known today as network science, what was originally a theoretical study of graphs has grown into a more scientific exploration of communities…

Quantitative Methods · Quantitative Biology 2020-01-01 Ryan E. Langendorf , Debra S. Goldberg

Graphs are commonly used in mathematics to represent some relationships between items. However, as simple objects, they sometimes fail to capture all relevant aspects of real-world data. To address this problem, we generalize them and model…

Social and Information Networks · Computer Science 2019-10-04 Pimprenelle Parmentier , Tiphaine Viard , Benjamin Renoust , Jean-François Baffier

Biological and cellular systems are often modeled as graphs in which vertices represent objects of interest (genes, proteins, drugs) and edges represent relational ties among these objects (binds-to, interacts-with, regulates). This…

Machine Learning · Statistics 2017-03-16 Jose Lugo-Martinez , Predrag Radivojac

Different graph generalizations have been recently used in an ad-hoc manner to represent multilayer networks, i.e. systems formed by distinct layers where each layer can be seen as a network. Similar constructions have also been used to…

Discrete Mathematics · Computer Science 2016-09-30 Klaus Wehmuth , Éric Fleury , Artur Ziviani

Protein subcellular localization is an important factor in normal cellular processes and disease. While many protein localization resources treat it as static, protein localization is dynamic and heavily influenced by biological context.…

Molecular Networks · Quantitative Biology 2022-12-13 Chris S. Magnano , Anthony Gitter

Despite their widespread utility across domains, basic network models face fundamental limitations when applied to complex biological systems, particularly in neuroscience. This paper critically examines these limitations and explores…

Other Quantitative Biology · Quantitative Biology 2024-11-07 Luiz Pessoa

In network science complex systems are represented as a mathematical graphs consisting of a set of nodes representing the components and a set of edges representing their interactions. The framework of networks has led to significant…

Physics and Society · Physics 2022-04-07 Alexandre Bovet , Hernán A. Makse

Relationship between agents can be conveniently represented by graphs. When these relationships have different modalities, they are better modelled by multilayer graphs where each layer is associated with one modality. Such graphs arise…

Machine Learning · Statistics 2021-03-05 Guillaume Braun , Hemant Tyagi , Christophe Biernacki