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Distant metastases (DM) refer to the dissemination of tumors, usually, beyond the organ where the tumor originated. They are the leading cause of death in patients with soft-tissue sarcomas (STSs). Positron emission tomography-computed…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Yige Peng , Lei Bi , Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

Gross tumor volume (GTV) delineation on tomography medical imaging is crucial for radiotherapy planning and cancer diagnosis. Convolutional neural networks (CNNs) has been predominated on automatic 3D medical segmentation tasks, including…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Chun-Hung Chao , Hsien-Tzu Cheng , Tsung-Ying Ho , Le Lu , Min Sun

Deep learning presents novel opportunities for the auto-segmentation of gross tumor volume (GTV) in head and neck cancer (HNC), yet fully automatic methods usually necessitate significant manual refinement. This study investigates the…

Medical Physics · Physics 2025-01-03 Jintao Ren , Mathis Rasmussen , Jasper Nijkamp , Jesper Grau Eriksen , Stine Korreman

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

Perimetric measurements provide insight into a patient's peripheral vision and day-to-day functioning and are the main outcome measure for identifying progression of visual damage from glaucoma. However, visual field data can be noisy,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Sean Wu , Jun Yu Chen , Vahid Mohammadzadeh , Sajad Besharati , Jaewon Lee , Kouros Nouri-Mahdavi , Joseph Caprioli , Zhe Fei , Fabien Scalzo

Efficient, reliable and reproducible target volume delineation is a key step in the effective planning of breast radiotherapy. However, post-operative breast target delineation is challenging as the contrast between the tumor bed volume…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Mahdieh Kazemimoghadam , Weicheng Chi , Asal Rahimi , Nathan Kim , Prasanna Alluri , Chika Nwachukwu , Weiguo Lu , Xuejun Gu

Tomography medical imaging is essential in the clinical workflow of modern cancer radiotherapy. Radiation oncologists identify cancerous tissues, applying delineation on treatment regions throughout all image slices. This kind of task is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-08 Chun-Hung Chao , Yen-Chi Cheng , Hsien-Tzu Cheng , Chi-Wen Huang , Tsung-Ying Ho , Chen-Kan Tseng , Le Lu , Min Sun

In order to optimize the radiotherapy delivery for cancer treatment, especially when dealing with complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI), the accurate contouring of the Planning Target Volume (PTV) is…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Ricardo Coimbra Brioso , Damiano Dei , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Finding, identifying and segmenting suspicious cancer metastasized lymph nodes from 3D multi-modality imaging is a clinical task of paramount importance. In radiotherapy, they are referred to as Lymph Node Gross Tumor Volume (GTVLN).…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Zhuotun Zhu , Dakai Jin , Ke Yan , Tsung-Ying Ho , Xianghua Ye , Dazhou Guo , Chun-Hung Chao , Jing Xiao , Alan Yuille , Le Lu

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

Medical Physics · Physics 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

Tumor growth prediction, a highly challenging task, has long been viewed as a mathematical modeling problem, where the tumor growth pattern is personalized based on imaging and clinical data of a target patient. Though mathematical models…

Computer Vision and Pattern Recognition · Computer Science 2017-06-05 Ling Zhang , Le Lu , Ronald M. Summers , Electron Kebebew , Jianhua Yao

Prediction of survivability in a patient for tumor progression is useful to estimate the effectiveness of a treatment protocol. In our work, we present a model to take into account the heterogeneous nature of a tumor to predict survival.…

Gross tumor volume (GTV) segmentation is a critical step in esophageal cancer radiotherapy treatment planning. Inconsistencies across oncologists and prohibitive labor costs motivate automated approaches for this task. However, leading…

Image and Video Processing · Electrical Eng. & Systems 2019-09-09 Dakai Jin , Dazhou Guo , Tsung-Ying Ho , Adam P. Harrison , Jing Xiao , Chen-kan Tseng , Le Lu

Vestibular schwannomas (VS) are benign tumors that are generally managed by active surveillance with MRI examination. To further assist clinical decision-making and avoid overtreatment, an accurate prediction of tumor growth based on…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Yunjie Chen , Jelmer M. Wolterink , Olaf M. Neve , Stephan R. Romeijn , Berit M. Verbist , Erik F. Hensen , Qian Tao , Marius Staring

While deep learning has exhibited remarkable predictive capabilities in various medical image tasks, its inherent black-box nature has hindered its widespread implementation in real-world healthcare settings. Our objective is to unveil the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Han Yuan , Lican Kang , Yong Li

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yan Wang , Xu Wei , Fengze Liu , Jieneng Chen , Yuyin Zhou , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yuzhen Ding , Hongying Feng , Yunze Yang , Jason Holmes , Zhengliang Liu , David Liu , William W. Wong , Nathan Y. Yu , Terence T. Sio , Steven E. Schild , Baoxin Li , Wei Liu

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah