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Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

Deep Learning of neural networks has progressively become more prominent in healthcare with models reaching, or even surpassing, expert accuracy levels. However, these success stories are tainted by concerning reports on the lack of model…

Machine Learning · Computer Science 2021-11-02 Matthew Watson , Bashar Awwad Shiekh Hasan , Noura Al Moubayed

Self-driving cars increasingly rely on deep neural networks to achieve human-like driving. The opacity of such black-box planners makes it challenging for the human behind the wheel to accurately anticipate when they will fail, with…

Explainable Artificial Intelligence has gained significant attention due to the widespread use of complex deep learning models in high-stake domains such as medicine, finance, and autonomous cars. However, different explanations often…

Artificial Intelligence · Computer Science 2024-04-17 Weronika Hryniewska-Guzik , Luca Longo , Przemysław Biecek

Deep neural networks have been well-known for their superb handling of various machine learning and artificial intelligence tasks. However, due to their over-parameterized black-box nature, it is often difficult to understand the prediction…

Machine Learning · Computer Science 2022-07-18 Xuhong Li , Haoyi Xiong , Xingjian Li , Xuanyu Wu , Xiao Zhang , Ji Liu , Jiang Bian , Dejing Dou

Deep neural networks are becoming more and more popular due to their revolutionary success in diverse areas, such as computer vision, natural language processing, and speech recognition. However, the decision-making processes of these…

Computation and Language · Computer Science 2021-10-15 Oana-Maria Camburu

Accurate mortality prediction allows Intensive Care Units (ICUs) to adequately benchmark clinical practice and identify patients with unexpected outcomes. Traditionally, simple statistical models have been used to assess patient death risk,…

Machine Learning · Computer Science 2020-05-20 William Caicedo-Torres , Jairo Gutierrez

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

The ability to explain decisions made by AI systems is highly sought after, especially in domains where human lives are at stake such as medicine or autonomous vehicles. While it is often possible to approximate the input-output relations…

Artificial Intelligence · Computer Science 2020-10-15 Daniel C. Elton

Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the…

Machine Learning · Computer Science 2017-07-18 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

The application of deep learning models in medical diagnosis has showcased considerable efficacy in recent years. Nevertheless, a notable limitation involves the inherent lack of explainability during decision-making processes. This study…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Konstantinos Pasvantis , Eftychios Protopapadakis

Although deep models achieve high predictive performance, it is difficult for humans to understand the predictions they made. Explainability is important for real-world applications to justify their reliability. Many example-based…

Machine Learning · Statistics 2021-12-08 Tomoharu Iwata , Yuya Yoshikawa

Deep neural networks are widely used for classification. These deep models often suffer from a lack of interpretability -- they are particularly difficult to understand because of their non-linear nature. As a result, neural networks are…

Artificial Intelligence · Computer Science 2017-11-22 Oscar Li , Hao Liu , Chaofan Chen , Cynthia Rudin

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Predicting in-hospital mortality for intensive care unit (ICU) patients is key to final clinical outcomes. AI has shown advantaged accuracy but suffers from the lack of explainability. To address this issue, this paper proposes an…

Machine Learning · Computer Science 2024-01-01 Xingqiao Li , Jindong Gu , Zhiyong Wang , Yancheng Yuan , Bo Du , Fengxiang He

Causal approaches to post-hoc explainability for black-box prediction models (e.g., deep neural networks trained on image pixel data) have become increasingly popular. However, existing approaches have two important shortcomings: (i) the…

Machine Learning · Computer Science 2025-08-12 Numair Sani , Daniel Malinsky , Ilya Shpitser

Deep learning has become the dominant approach for creating high capacity, scalable models across diverse data modalities. However, because these models rely on a large number of learned parameters, tightly couple feature extraction with…

Artificial Intelligence · Computer Science 2026-05-12 Adam Gould , Francesca Toni

Deep neural networks have exhibited remarkable performance across a wide range of real-world tasks. However, comprehending the underlying reasons for their effectiveness remains a challenging problem. Interpreting deep neural networks…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Chenxu Zhao , Wei Qian , Yucheng Shi , Mengdi Huai , Ninghao Liu

There have been several post-hoc explanation approaches developed to explain pre-trained black-box neural networks. However, there is still a gap in research efforts toward designing neural networks that are inherently explainable. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Subash Khanal , Benjamin Brodie , Xin Xing , Ai-Ling Lin , Nathan Jacobs

In the intensive care unit, the underlying causes of critical illness vary substantially across diagnoses, yet prediction models accounting for diagnostic heterogeneity have not been systematically studied. To address the gap, we evaluate…

Machine Learning · Computer Science 2025-12-09 Mengqi Xu , Subha Maity , Joel Dubin