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Generative modeling of single-cell RNA-seq data is crucial for tasks like trajectory inference, batch effect removal, and simulation of realistic cellular data. However, recent deep generative models simulating synthetic single cells from…

Quantitative Methods · Quantitative Biology 2025-03-04 Alessandro Palma , Till Richter , Hanyi Zhang , Manuel Lubetzki , Alexander Tong , Andrea Dittadi , Fabian Theis

Scene generation has extensive industrial applications, demanding both high realism and precise control over geometry and appearance. Language-driven retrieval methods compose plausible scenes from a large object database, but overlook…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Zhifei Yang , Guangyao Zhai , Keyang Lu , YuYang Yin , Chao Zhang , Zhen Xiao , Jieyi Long , Nassir Navab , Yikai Wang

Normalizing Flows (NFs) are able to model complicated distributions p(y) with strong inter-dimensional correlations and high multimodality by transforming a simple base density p(z) through an invertible neural network under the change of…

Machine Learning · Computer Science 2023-11-14 Christina Winkler , Daniel Worrall , Emiel Hoogeboom , Max Welling

In the past few years, deep generative models, such as generative adversarial networks \autocite{GAN}, variational autoencoders \autocite{vaepaper}, and their variants, have seen wide adoption for the task of modelling complex data…

Machine Learning · Statistics 2020-09-02 Guilherme G. P. Freitas Pires , Mário A. T. Figueiredo

Unlike cloud-based deep learning models that are often large and uniform, edge-deployed models usually demand customization for domain-specific tasks and resource-limited environments. Such customization processes can be costly and…

Artificial Intelligence · Computer Science 2023-08-30 Wenxing Xu , Yuanchun Li , Jiacheng Liu , Yi Sun , Zhengyang Cao , Yixuan Li , Hao Wen , Yunxin Liu

Existing approaches to controllable generation typically rely on fine-tuning, auxiliary networks, or test-time search. We show that flow matching admits a different control interface: adaptation through examples. For deterministic…

Machine Learning · Computer Science 2026-05-26 Pedro M. P. Curvo , Maksim Zhdanov , Floor Eijkelboom , Jan-Willem van de Meent

MeanFlow (MF) has recently been established as a framework for one-step generative modeling. However, its ``fastforward'' nature introduces key challenges in both the training objective and the guidance mechanism. First, the original MF's…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zhengyang Geng , Yiyang Lu , Zongze Wu , Eli Shechtman , J. Zico Kolter , Kaiming He

Normalizing flows transform a latent distribution through an invertible neural network for a flexible and pleasingly simple approach to generative modelling, while preserving an exact likelihood. We propose FlowGMM, an end-to-end approach…

Machine Learning · Computer Science 2020-01-01 Pavel Izmailov , Polina Kirichenko , Marc Finzi , Andrew Gordon Wilson

Generative diffusion models have shown empirical successes in point cloud resampling, generating a denser and more uniform distribution of points from sparse or noisy 3D point clouds by progressively refining noise into structure. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Wenqiang Xu , Wenrui Dai , Duoduo Xue , Ziyang Zheng , Chenglin Li , Junni Zou , Hongkai Xiong

Diffusion and flow-based models have become the state of the art for generative AI across a wide range of data modalities, including images, videos, shapes, molecules, music, and more. This tutorial provides a self-contained introduction to…

Machine Learning · Computer Science 2026-03-19 Peter Holderrieth , Ezra Erives

Diffusion-based generative models have greatly impacted the speech processing field in recent years, exhibiting high speech naturalness and spawning a new research direction. Their application in real-time communication is, however, still…

Signal Processing · Electrical Eng. & Systems 2026-04-22 Simon Welker , Bunlong Lay , Maris Hillemann , Tal Peer , Timo Gerkmann

Based on a natural connection between ResNet and transport equation or its characteristic equation, we propose a continuous flow model for both ResNet and plain net. Through this continuous model, a ResNet can be explicitly constructed as a…

Machine Learning · Computer Science 2017-12-12 Zhen Li , Zuoqiang Shi

Flow-based generative models (Dinh et al., 2014) are conceptually attractive due to tractability of the exact log-likelihood, tractability of exact latent-variable inference, and parallelizability of both training and synthesis. In this…

Machine Learning · Statistics 2018-07-11 Diederik P. Kingma , Prafulla Dhariwal

We propose a framework using normalizing-flow based models, SELF-Referencing Embedded Strings, and multi-objective optimization that efficiently generates small molecules. With an initial training set of only 100 small molecules, FastFlows…

Chemical Physics · Physics 2022-02-01 Nathan C. Frey , Vijay Gadepally , Bharath Ramsundar

Point cloud upsampling aims to generate dense point clouds from given sparse ones, which is a challenging task due to the irregular and unordered nature of point sets. To address this issue, we present a novel deep learning-based model,…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Aihua Mao , Zihui Du , Junhui Hou , Yaqi Duan , Yong-jin Liu , Ying He

Graph generation aims to sample discrete node and edge attributes while satisfying coupled structural constraints. Diffusion models for graphs often adopt largely factorized forward-noising, and many flow-matching methods start from…

Machine Learning · Computer Science 2026-02-02 Yida Xiong , Jiameng Chen , Xiuwen Gong , Jia Wu , Shirui Pan , Wenbin Hu

We propose a novel approach for probabilistic generative modeling of 3D shapes. Unlike most existing models that learn to deterministically translate a latent vector to a shape, our model, Point-Voxel Diffusion (PVD), is a unified,…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Linqi Zhou , Yilun Du , Jiajun Wu

Face animation has achieved much progress in computer vision. However, prevailing GAN-based methods suffer from unnatural distortions and artifacts due to sophisticated motion deformation. In this paper, we propose a Face Animation…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Bohan Zeng , Xuhui Liu , Sicheng Gao , Boyu Liu , Hong Li , Jianzhuang Liu , Baochang Zhang

We present a novel, conditional generative probabilistic model of set-valued data with a tractable log density. This model is a continuous normalizing flow governed by permutation equivariant dynamics. These dynamics are driven by a…

The Generative Flow Network is a probabilistic framework where an agent learns a stochastic policy for object generation, such that the probability of generating an object is proportional to a given reward function. Its effectiveness has…

Machine Learning · Computer Science 2022-10-10 Ling Pan , Dinghuai Zhang , Aaron Courville , Longbo Huang , Yoshua Bengio