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Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

Populations and Evolution · Quantitative Biology 2010-11-25 Christel Kamp

The epidemic spreading of a disease can be described by a contact network whose nodes are persons or centers of contagion and links heterogeneous relations among them. We provide a procedure to identify multiple sources of an outbreak or…

Mathematical Physics · Physics 2012-11-13 Vincenzo Fioriti , Marta Chinnici

Stochasticity and spatial heterogeneity are of great interest recently in studying the spread of an infectious disease. The presented method solves an inverse problem to discover the effectively decisive topology of a heterogeneous network…

Artificial Intelligence · Computer Science 2015-03-13 Yoshiharu Maeno

Uncertainty can be classified as either aleatoric (intrinsic randomness) or epistemic (imperfect knowledge of parameters). The majority of frameworks assessing infectious disease risk consider only epistemic uncertainty. We only ever…

Inferring the input parameters of simulators from observations is a crucial challenge with applications from epidemiology to molecular dynamics. Here we show a simple approach in the regime of sparse data and approximately correct models,…

Methodology · Statistics 2022-04-06 Rainier Barrett , Mehrad Ansari , Gourab Ghoshal , Andrew D White

The susceptible--infected--susceptible (SIS) epidemic process on complex networks can show metastability, resembling an endemic equilibrium. In a general setting, the metastable state may involve a large portion of the network, or it can be…

Physics and Society · Physics 2016-05-03 Faryad Darabi Sahneh , Aram Vajdi , Caterina Scoglio

Maximum entropy modeling is a flexible and popular framework for formulating statistical models given partial knowledge. In this paper, rather than the traditional method of optimizing over the continuous density directly, we learn a smooth…

Methodology · Statistics 2017-05-01 Gabriel Loaiza-Ganem , Yuanjun Gao , John P. Cunningham

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

Accurate and reliable forecasting of epidemic incidences is critical for public health preparedness, yet it remains a challenging task due to complex nonlinear temporal dependencies and heterogeneous spatial interactions. Often, point…

Machine Learning · Statistics 2026-03-10 Rajdeep Pathak , Tanujit Chakraborty

The principle of maximum entropy provides a useful method for inferring statistical mechanics models from observations in correlated systems, and is widely used in a variety of fields where accurate data are available. While the assumptions…

Neurons and Cognition · Quantitative Biology 2017-06-02 Ulisse Ferrari , Tomoyuki Obuchi , Thierry Mora

Maximum entropy models provide the least constrained probability distributions that reproduce statistical properties of experimental datasets. In this work we characterize the learning dynamics that maximizes the log-likelihood in the case…

Disordered Systems and Neural Networks · Physics 2016-09-21 Ulisse Ferrari

Infectious disease outbreaks have precipitated a profusion of mathematical models. Epidemic curves predicted by these models are typically qualitatively similar, despite distinct model assumptions, but there is no theoretical explanation…

Populations and Evolution · Quantitative Biology 2026-02-23 David J. D. Earn , Todd L. Parsons

To understand the contact patterns of a population -- who is in contact with whom, and when the contacts happen -- is crucial for modeling outbreaks of infectious disease. Traditional theoretical epidemiology assumes that any individual can…

Populations and Evolution · Quantitative Biology 2015-10-22 Petter Holme

The reconstruction of missing information in epidemic spreading on contact networks can be essential in the prevention and containment strategies. The identification and warning of infectious but asymptomatic individuals (i.e., contact…

Social and Information Networks · Computer Science 2022-11-21 Indaco Biazzo , Alfredo Braunstein , Luca Dall'Asta , Fabio Mazza

The principle of maximum entropy is a broadly applicable technique for computing a distribution with the least amount of information possible constrained to match empirical data, for instance, feature expectations. We seek to generalize…

Information Theory · Computer Science 2022-05-30 Kenneth Bogert

We study the problem of identifying the source of emerging large-scale outbreaks of foodborne disease. To solve the source identification problem we formulate a probabilistic model of the contamination diffusion process as a random walk on…

Physics and Society · Physics 2018-05-09 Abigail L. Horn , Hanno Friedrich

The broad abundance of time series data, which is in sharp contrast to limited knowledge of the underlying network dynamic processes that produce such observations, calls for a rigorous and efficient method of causal network inference. Here…

Information Theory · Computer Science 2015-05-19 Jie Sun , Dane Taylor , Erik M. Bollt

Background: The global spread of the severe acute respiratory syndrome (SARS) epidemic has clearly shown the importance of considering the long-range transportation networks in the understanding of emerging diseases outbreaks. The…

Other Quantitative Biology · Quantitative Biology 2008-01-16 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alessandro Vespignani

A model based on a thermodynamic approach is proposed for predicting the dynamics of communicable epidemics in a city, when the epidemic is governed by controlling efforts of multiple scales so that an entropy is associated with the system.…

Medical Physics · Physics 2013-10-01 W. B. Wang , Z. N. Wu , Z. M. Cao , R. F. Hu

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer