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In this study, we develop a methodology for model reduction and selection informed by global sensitivity analysis (GSA) methods. We apply these techniques to a control model that takes systolic blood pressure and thoracic tissue pressure…

Quantitative Methods · Quantitative Biology 2021-05-17 E. Benjamin Randall , Nicholas Z. Randolph , Alen Alexanderian , Mette S. Olufsen

We give methods for Bayesian inference of directed acyclic graphs, DAGs, and the induced causal effects from passively observed complete data. Our methods build on a recent Markov chain Monte Carlo scheme for learning Bayesian networks,…

Machine Learning · Computer Science 2020-11-19 Jussi Viinikka , Antti Hyttinen , Johan Pensar , Mikko Koivisto

The development of chemical reaction models aids understanding and prediction in areas ranging from biology to electrochemistry and combustion. A systematic approach to building reaction network models uses observational data not only to…

Computational Engineering, Finance, and Science · Computer Science 2019-01-23 Nikhil Galagali , Youssef M. Marzouk

Machine learning provides algorithms that can learn from data and make inferences or predictions on data. Bayesian networks are a class of graphical models that allow to represent a collection of random variables and their condititional…

Artificial Intelligence · Computer Science 2019-01-08 Robert Leppert , Karl-Heinz Zimmermann

Bayesian network is a complete model for the variables and their relationships, it can be used to answer probabilistic queries about them. A Bayesian network can thus be considered a mechanism for automatically applying Bayes' theorem to…

Artificial Intelligence · Computer Science 2010-11-08 Jianguo Ding

This paper looks at the task of network topology inference, where the goal is to learn an unknown graph from nodal observations. One of the novelties of the approach put forth is the consideration of prior information about the density of…

Signal Processing · Electrical Eng. & Systems 2022-07-12 Samuel Rey , T. Mitchell Roddenberry , Santiago Segarra , Antonio G. Marques

We consider the problem of analyzing the heterogeneity of clustering distributions for multiple groups of observed data, each of which is indexed by a covariate value, and inferring global clusters arising from observations aggregated over…

Methodology · Statistics 2012-12-06 XuanLong Nguyen

This paper studies the problem of globally optimizing a variable of interest that is part of a causal model in which a sequence of interventions can be performed. This problem arises in biology, operational research, communications and,…

Machine Learning · Statistics 2020-05-27 Virginia Aglietti , Xiaoyu Lu , Andrei Paleyes , Javier González

The so-called polynomial chaos expansion is widely used in computer experiments. For example, it is a powerful tool to estimate Sobol' sensitivity indices. In this paper, we consider generalized chaos expansions built on general tensor…

Statistics Theory · Mathematics 2019-06-25 O Roustant , F. Gamboa , B Iooss

The formulation of Bayesian inverse problems involves choosing prior distributions; choices that seem equally reasonable may lead to significantly different conclusions. We develop a computational approach to better understand the impact of…

Computation · Statistics 2026-01-08 John E. Darges , Alen Alexanderian , Pierre A. Gremaud

Computing the exact likelihood of data in large Bayesian networks consisting of thousands of vertices is often a difficult task. When these models contain many deterministic conditional probability tables and when the observed values are…

Computation · Statistics 2012-06-26 Ydo Wexler , Dan Geiger

Global sensitivity analysis (GSA) of numerical simulators aims at studying the global impact of the input uncertainties on the output. To perform the GSA, statistical tools based on inputs/output dependence measures are commonly used. We…

Statistics Theory · Mathematics 2019-02-20 Anouar Meynaoui , Amandine Marrel , Béatrice Laurent

A novel theoretical and numerical framework for the estimation of Sobol sensitivity indices for models in which inputs are confined to a non-rectangular domain (e.g., in presence of inequality constraints) is developed. Two numerical…

Statistics Theory · Mathematics 2016-05-18 S. Kucherenko , O. V. Klymenko , N. Shah

With the advance of efficient analytical methods for sensitivity analysis ofprobabilistic networks, the interest in the sensitivities revealed by real-life networks is rekindled. As the amount of data resulting from a sensitivity analysis…

Artificial Intelligence · Computer Science 2013-01-14 Linda C. van der Gaag , Silja Renooij

The identification of important nodes in complex networks is an area of exciting growth due to its applications across various disciplines like disease controlling, community finding, data mining, network system controlling, just to name a…

Social and Information Networks · Computer Science 2020-11-13 Qiuyan Shang , Yong Deng , Kang Hao Cheong

We consider the problem of efficiently inferring interventional distributions in a causal Bayesian network from a finite number of observations. Let $\mathcal{P}$ be a causal model on a set $\mathbf{V}$ of observable variables on a given…

Data Structures and Algorithms · Computer Science 2021-07-28 Arnab Bhattacharyya , Sutanu Gayen , Saravanan Kandasamy , Vedant Raval , N. V. Vinodchandran

Knowing which nodes are influential in a complex network and whether the network can be influenced by a small subset of nodes is a key part of network analysis. However, many traditional measures of importance focus on node level…

Physics and Society · Physics 2023-06-27 Niall Rodgers , Peter Tino , Samuel Johnson

Variance-based global sensitivity analysis, in particular Sobol' analysis, is widely used for determining the importance of input variables to a computational model. Sobol' indices can be computed cheaply based on spectral methods like…

When network and graph theory are used in the study of complex systems, a typically finite set of nodes of the network under consideration is frequently either explicitly or implicitly considered representative of a much larger finite or…

Data Analysis, Statistics and Probability · Physics 2015-03-18 Jobst Heitzig , Jonathan F. Donges , Yong Zou , Norbert Marwan , Jürgen Kurths

Network metrics form a fundamental part of the network analysis toolbox. Used to quantitatively measure different aspects of the network, these metrics can give insights into the underlying network structure and function. In this work, we…

Machine Learning · Statistics 2015-06-04 Harold Soh