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This paper is devoted to the study of a stochastic epidemiological model which is a variant of the SIR model to which we add an extra factor in the transition rate from susceptible to infected accounting for the inflow of infection due to…

Analysis of PDEs · Mathematics 2021-06-29 Gadi Fibich , Samuel Nordmann

Estimating population-level prevalence and transmission dynamics of wildlife pathogens can be challenging, partly because surveillance data is sparse, detection-driven, and unevenly sequenced. Using highly pathogenic avian influenza A/H5…

Populations and Evolution · Quantitative Biology 2026-01-16 Haley Stone , Jing Du , Yang Yang , Ashna Desai , Rebecca Dawson , Hao Xue , David Heslop , Matthew Scotch , Andreas Züfle , C. Raina MacIntyre , Flora Salim

In this work, we aim to formalize a novel scientific machine learning framework to reconstruct the hidden dynamics of the transmission rate, whose inaccurate extrapolation can significantly impair the quality of the epidemic forecasts, by…

Quantitative Methods · Quantitative Biology 2024-10-16 Giovanni Ziarelli , Stefano Pagani , Nicola Parolini , Francesco Regazzoni , Marco Verani

We study two simple mathematical models of the epidemic. At first, we study the repetitive infection spreading in a simplified SIRS model including the effect of the decay of the acquired immune. The model is an intermediate model of the…

Populations and Evolution · Quantitative Biology 2024-03-13 Hidetsugu Sakaguchi , Keito Yamasaki

When deploying time series forecasting models based on machine learning to real world settings, one often encounter situations where the data distribution drifts. Such drifts expose the forecasting models to out-of-distribution (OOD) data,…

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

This work examines the discrete-time networked SIR (susceptible-infected-recovered) epidemic model, where the infection and recovery parameters may be time-varying. We provide a sufficient condition for the SIR model to converge to the set…

Systems and Control · Electrical Eng. & Systems 2021-03-01 Ciyuan Zhang , Humphrey Leung , Brooks Butler , Philip. E. Paré

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

We develop a feedback control method for networked epidemic spreading processes. In contrast to most prior works which consider mean field, open-loop control schemes, the present work develops a novel framework for feedback control of…

Optimization and Control · Mathematics 2017-03-23 Nicholas J. Watkins , Cameron Nowzari , George J. Pappas

In two previous papers, I introduced SuperSpreader (SS) epidemic models, offered some theoretical discussion of prevention issues, and fitted some models to data derived from published accounts of the ongoing MERS epidemic (concluding that…

Populations and Evolution · Quantitative Biology 2014-06-24 W. David Wick

This work introduces a physics-informed neural networks (PINNs)-based model predictive control (MPC) framework for susceptible-infected-recovered ($SIR$) spreading models. Existing studies in MPC design for epidemic control often assume…

Machine Learning · Computer Science 2025-09-17 Aiping Zhong , Baike She , Philip E. Paré

In network-based SIS models of infectious disease transmission, infection can only occur between directly connected individuals. This constraint naturally gives rise to spatial correlations between the states of neighboring nodes, as the…

Statistical Mechanics · Physics 2026-03-18 Alexander Leibenzon , Samuel W. S. Johnson , Ruth E. Baker , Michael Assaf

We study the susceptible-infective-recovered (SIR) epidemic on a random graph chosen uniformly subject to having given vertex degrees. In this model infective vertices infect each of their susceptible neighbours, and recover, at a constant…

Probability · Mathematics 2014-09-24 Svante Janson , Malwina Luczak , Peter Windridge

Pairwise models are used widely to model epidemic spread on networks. These include the modelling of susceptible-infected-removed (SIR) epidemics on regular networks and extensions to SIS dynamics and contact tracing on more exotic networks…

Populations and Evolution · Quantitative Biology 2018-09-24 István Z. Kiss , Joel C. Miller , Péter L. Simon

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

Reaction-diffusion epidemic models with vital dynamics are an important framework for describing the spatial and temporal spread of infectious diseases. In this work, we present a constraint-aware, physics-informed neural network (PINN)…

Dynamical Systems · Mathematics 2026-05-20 Achraf Zinihi , Matthias Ehrhardt

Objectives: Our research adopts computational techniques to analyze disease outbreaks weekly over a large geographic area while maintaining local-level analysis by incorporating relevant high-spatial resolution cultural and environmental…

Machine Learning · Computer Science 2024-11-12 Scott Pezanowski , Etien Luc Koua , Joseph C Okeibunor , Abdou Salam Gueye

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

In this paper, we propose an SIR spread model in a population network coupled with an infrastructure network that has a pathogen spreading in it. We develop a threshold condition to characterize the monotonicity and peak time of a weighted…

Systems and Control · Electrical Eng. & Systems 2026-04-08 José I. Caiza , Junjie Qin , Philip E. Paré

Compartmental models, especially the Susceptible-Infected-Removed (SIR) model, have long been used to understand the behaviour of various diseases. Allowing parameters, such as the transmission rate, to be time-dependent functions makes it…

Methodology · Statistics 2024-09-27 Son Luu , Edward Susko , Lam Si Tung Ho
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