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Related papers: Interpretable Machine Learning for Genomics

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We present a brief history of the field of interpretable machine learning (IML), give an overview of state-of-the-art interpretation methods, and discuss challenges. Research in IML has boomed in recent years. As young as the field is, it…

Machine Learning · Statistics 2022-01-24 Christoph Molnar , Giuseppe Casalicchio , Bernd Bischl

To learn about real world phenomena, scientists have traditionally used models with clearly interpretable elements. However, modern machine learning (ML) models, while powerful predictors, lack this direct elementwise interpretability (e.g.…

Machine Learning · Statistics 2024-07-16 Timo Freiesleben , Gunnar König , Christoph Molnar , Alvaro Tejero-Cantero

Interpretability can be critical for the safe and responsible use of machine learning models in high-stakes applications. So far, evolutionary computation (EC), in particular in the form of genetic programming (GP), represents a key enabler…

Neural and Evolutionary Computing · Computer Science 2022-04-06 Marco Virgolin , Eric Medvet , Tanja Alderliesten , Peter A. N. Bosman

Interpretable machine learning tackles the important problem that humans cannot understand the behaviors of complex machine learning models and how these models arrive at a particular decision. Although many approaches have been proposed, a…

Machine Learning · Computer Science 2019-05-21 Mengnan Du , Ninghao Liu , Xia Hu

Despite increasing interest in the field of Interpretable Machine Learning (IML), a significant gap persists between the technical objectives targeted by researchers' methods and the high-level goals of consumers' use cases. In this work,…

Machine Learning · Computer Science 2021-07-30 Valerie Chen , Jeffrey Li , Joon Sik Kim , Gregory Plumb , Ameet Talwalkar

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

Interpretability in machine learning (ML) is crucial for high stakes decisions and troubleshooting. In this work, we provide fundamental principles for interpretable ML, and dispel common misunderstandings that dilute the importance of this…

Machine Learning · Computer Science 2021-09-02 Cynthia Rudin , Chaofan Chen , Zhi Chen , Haiyang Huang , Lesia Semenova , Chudi Zhong

Artificial Intelligence (AI) and its data-centric branch of machine learning (ML) have greatly evolved over the last few decades. However, as AI is used increasingly in real world use cases, the importance of the interpretability of and…

Machine Learning · Computer Science 2022-12-01 N. Ranasinghe , A. Ramanan , S. Fernando , P. N. Hameed , D. Herath , T. Malepathirana , P. Suganthan , M. Niranjan , S. Halgamuge

New technologies have led to vast troves of large and complex datasets across many scientific domains and industries. People routinely use machine learning techniques to not only process, visualize, and make predictions from this big data,…

Machine Learning · Statistics 2023-08-04 Genevera I. Allen , Luqin Gan , Lili Zheng

Machine learning (ML) has seen significant growth in both popularity and importance. The high prediction accuracy of ML models is often achieved through complex black-box architectures that are difficult to interpret. This interpretability…

Machine Learning · Statistics 2024-07-29 David Köhler , David Rügamer , Matthias Schmid

With the spread and rapid advancement of black box machine learning models, the field of interpretable machine learning (IML) or explainable artificial intelligence (XAI) has become increasingly important over the last decade. This is…

In recent years, machine learning (ML) has become a key enabling technology for the sciences and industry. Especially through improvements in methodology, the availability of large databases and increased computational power, today's ML…

Artificial Intelligence · Computer Science 2019-09-27 Wojciech Samek , Klaus-Robert Müller

Interactive Machine Learning (IML) is an iterative learning process that tightly couples a human with a machine learner, which is widely used by researchers and practitioners to effectively solve a wide variety of real-world application…

Machine Learning · Computer Science 2018-11-13 Liu Jiang , Shixia Liu , Changjian Chen

Interpretable machine learning has exploded as an area of interest over the last decade, sparked by the rise of increasingly large datasets and deep neural networks. Simultaneously, large language models (LLMs) have demonstrated remarkable…

Computation and Language · Computer Science 2024-02-06 Chandan Singh , Jeevana Priya Inala , Michel Galley , Rich Caruana , Jianfeng Gao

Interpretable machine learning (IML) becomes increasingly important in highly regulated industry sectors related to the health and safety or fundamental rights of human beings. In general, the inherently IML models should be adopted because…

Machine Learning · Computer Science 2021-11-03 Agus Sudjianto , Aijun Zhang

The use of machine learning (ML) techniques in the biomedical field has become increasingly important, particularly with the large amounts of data generated by the aftermath of the COVID-19 pandemic. However, due to the complex nature of…

Machine Learning · Computer Science 2023-03-17 Anthony Onoja , Francesco Raimondi

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Artificial intelligence (AI) provides many opportunities to improve private and public life. Discovering patterns and structures in large troves of data in an automated manner is a core component of data science, and currently drives…

Machine Learning · Computer Science 2020-09-25 Vaishak Belle , Ioannis Papantonis

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

Machine Learning · Computer Science 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

This paper presents a systematic literature review (SLR) on the explainability and interpretability of machine learning (ML) models within the context of predictive process mining, using the PRISMA framework. Given the rapid advancement of…

Machine Learning · Computer Science 2024-01-01 Nijat Mehdiyev , Maxim Majlatow , Peter Fettke
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