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Regenerating codes allow distributed storage systems to recover from the loss of a storage node while transmitting the minimum possible amount of data across the network. We present a systematic computer search for optimal systematic…

Information Theory · Computer Science 2009-10-14 Daniel Cullina , Alexandros G. Dimakis , Tracey Ho

Diffraction drastically limits the bit density in optical data storage. To increase the storage density, alternative strategies involving supplementary recording dimensions and robust read-out schemes must be explored. Here, we propose to…

Applied Physics · Physics 2020-01-28 Peter R. Wiecha , Aurélie Lecestre , Nicolas Mallet , Guilhem Larrieu

In this paper we study error-correcting codes for the storage of data in synthetic deoxyribonucleic acid (DNA). We investigate a storage model where a data set is represented by an unordered set of $M$ sequences, each of length $L$. Errors…

Information Theory · Computer Science 2020-02-13 Andreas Lenz , Paul H. Siegel , Antonia Wachter-Zeh , Eitan Yaakobi

This paper focuses on pattern matching in the DNA sequence. It was inspired by a previously reported method that proposes encoding both pattern and sequence using prime numbers. Although fast, the method is limited to rather small pattern…

Computer Vision and Pattern Recognition · Computer Science 2016-11-21 Janja Paliska Soldo , Ana Sovic Krzic , and Damir Sersic

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

Information Theory · Computer Science 2025-05-13 Yajuan Liu , Tolga M. Duman

This paper studies the sequence reconstruction problem for a channel inspired by protein identification. We introduce a coloring channel, where a sequence is transmitted through a channel that deletes all symbols not belonging to a fixed…

Information Theory · Computer Science 2025-08-05 Jessica Bariffi , Antonia Wachter-Zeh , Eitan Yaakobi

A number of methods have been proposed over the last decade for encoding information using deoxyribonucleic acid (DNA), giving rise to the emerging area of DNA data embedding. Since a DNA sequence is conceptually equivalent to a sequence of…

Information Theory · Computer Science 2014-10-09 Félix Balado

Thousands of users consult digital archives daily, but the information they can access is unrepresentative of the diversity of documentary history. The sequence-to-sequence architecture typically used for optical character recognition (OCR)…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 Jacob Carlson , Tom Bryan , Melissa Dell

The DNA cryptography is a new and very promising direction in cryptography research. DNA can be used in cryptography for storing and transmitting the information, as well as for computation. Although in its primitive stage, DNA cryptography…

Cryptography and Security · Computer Science 2012-03-07 Kang Ning

We propose an end-to-end recurrent encoder-decoder based sequence learning approach for printed text Optical Character Recognition (OCR). In contrast to present day existing state-of-art OCR solution which uses connectionist temporal…

Computer Vision and Pattern Recognition · Computer Science 2015-12-29 Devendra Kumar Sahu , Mohak Sukhwani

DNA is a promising storage medium, but its stability and occurrence of Indel errors pose a significant challenge. The relative occurrence of Guanine(G) and Cytosine(C) in DNA is crucial for its longevity, and reverse complementary base…

Information Theory · Computer Science 2024-01-15 NallappaBhavithran G , Selvakumar R

The general trace reconstruction problem seeks to recover an original sequence from its noisy copies independently corrupted by deletions, insertions, and substitutions. This problem arises in applications such as DNA data storage, a…

Machine Learning · Computer Science 2025-07-18 Franziska Weindel , Michael Girsch , Reinhard Heckel

DNA, with remarkable properties of high density, durability, and replicability, is one of the most appealing storage media. Emerging DNA storage technologies use composite DNA letters, where information is represented by probability…

Information Theory · Computer Science 2025-03-26 Wenkai Zhang , Zhiying Wang

In this paper, we consider the outer channel for DNA-based data storage. When transmitting over the outer channel, each DNA string is treated as a unit/symbol that would be either correctly received, or erased, or corrupted by uniformly…

Information Theory · Computer Science 2025-09-23 Xuan He , Yi Ding , Kui Cai , Guanghui Song , Bin Dai , Xiaohu Tang

High-density oligonucleotide arrays are among the most rapidly expanding technologies in biology today. In the {\sl GeneChip} system, the reconstruction of the target concentration depends upon the differential signal generated from…

Biological Physics · Physics 2009-11-07 Felix Naef , Daniel A. Lim , Nila Patil , Marcelo Magnasco

Codes have been used for centuries to convey secret information.To a cryptanalyst, the interception of a code is only the first step in recovering a secret message.Deoxyribonucleic acid (DNA) is a biological and molecular code.Through the…

Cryptography and Security · Computer Science 2008-01-31 O. Okunoye Babatunde

Since security is one of the most important issues, the evolve of cryptography and cryptographic analysis are considered as the fields of on-going research. The latest development on this field is DNA cryptography. It has emerged after the…

Cryptography and Security · Computer Science 2015-03-17 Beenish Anam , Kazi Sakib , Md. Alamgir Hossain , Keshav Dahal

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Biological data mainly comprises of Deoxyribonucleic acid (DNA) and protein sequences. These are the biomolecules which are present in all cells of human beings. Due to the self-replicating property of DNA, it is a key constitute of genetic…

Other Quantitative Biology · Quantitative Biology 2020-06-04 Shakeela Bibi , Javed Iqbal , Adnan Iftekhar , Mir Hassan

A simple DNA-based data storage scheme is demonstrated in which information is written using "addressing" oligonucleotides. In contrast to other methods that allow arbitrary code to be stored, the resulting DNA is suitable for downstream…

Emerging Technologies · Computer Science 2017-11-15 Gary M. Skinner , Koen Visscher , Masud Mansuripur