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This paper aims to evaluate the potential cost-effectiveness of healthcare interventions against human papillomavirus (HPV). For this, we consider a two-sex epidemic model for the transmission dynamics of HPV which includes screening,…
Automated detection and classification of cervical cells in conventional Pap smear images can strengthen cervical cancer screening at scale by reducing manual workload, improving triage, and increasing consistency across readers. However,…
Evaluating the performance of a prediction model is a common task in medical statistics. Standard accuracy metrics require the observation of the true outcomes. This is typically not possible in the setting with time-to-event outcomes due…
We propose a novel approach to cervical cell image classification for cervical cancer screening using the EVA-02 transformer model. We developed a four-step pipeline: fine-tuning EVA-02, feature extraction, selecting important features…
The primary goal of public health efforts to control HIV epidemics is to diagnose and treat people with HIV infection as soon as possible after seroconversion. The timing of initiation of antiretroviral therapy (ART) treatment after HIV…
Cervical cancer, the fourth leading cause of cancer in women globally, requires early detection through Pap smear tests to identify precancerous changes and prevent disease progression. In this study, we performed a focused analysis by…
Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…
Huntington disease (HD) is a neurodegenerative disease with progressively worsening symptoms. Accurately modeling time to HD diagnosis is essential for clinical trial design. Langbehn's model, the CAG-Age Product (CAP) model, the Prognostic…
Interval censored data commonly arise in medical studies when the event time of interest is only known to lie within an interval. In the presence of a cure subgroup, conventional mixture cure models typically assume a logistic model for the…
The onset of several silent, chronic diseases such as diabetes can be detected only through diagnostic tests. Due to cost considerations, self-reported outcomes are routinely collected in lieu of expensive diagnostic tests in large-scale…
This study investigates an inverse problem associated with a time-fractional HIV infection model incorporating nonlinear diffusion. The model describes the dynamics of uninfected target cells, infected cells, and free virus particles, where…
Human papillomavirus (HPV) is a significant public health concern, as it is a leading cause of cervical cancer in women. However, data on the prevalence of HPV infection among Iraqi women is scarce. This study aimed to estimate the…
Objective: Ultrahigh-resolution optical coherence microscopy (OCM) has recently demonstrated its potential for accurate diagnosis of human cervical diseases. One major challenge for clinical adoption, however, is the steep learning curve…
Human Papillomaviruses (HPV) are one of the most prevalent sexually transmitted infections (STI) and the most oncogenic viruses known to humans. The vast majority of HPV infections clear in less than 3 years, but the underlying mechanisms,…
Cervical cancer is a leading malignancy in female reproductive system. While AI-assisted cytology offers a cost-effective and non-invasive screening solution, current systems struggle with generalizability in complex clinical scenarios. To…
Since the onset of the COVID-19 pandemic in 2020, millions of people have succumbed to this deadly virus. Many attempts have been made to devise an automated method of testing that could detect the virus. Various researchers around the…
Extranodal extension (ENE) is an emerging prognostic factor in human papillomavirus (HPV)-associated oropharyngeal cancer (OPC), although it is currently omitted as a clinical staging criteria. Recent works have advocated for the inclusion…
Cervical cancer, one of the most common fatal cancers among women, can be prevented by regular screening to detect any precancerous lesions at early stages and treat them. Pap smear test is a widely performed screening technique for early…
Human papillomavirus (HPV) status is a critical determinant of prognosis and treatment response in head and neck and cervical cancers. Although attention-based multiple instance learning (MIL) achieves strong slide-level prediction for…
Cervical cancer is the seventh most common cancer among all the cancers worldwide and the fourth most common cancer among women. Cervical cytopathology image classification is an important method to diagnose cervical cancer. Manual…