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Single-particle cryo-electron microscopy (cryo-EM) is an emerging imaging modality capable of visualizing proteins and macro-molecular complexes at near-atomic resolution. The low electron-doses used to prevent sample radiation damage,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-24 Qinwen Huang , Ye Zhou , Xiaochen Du , Reed Chen , Jianyou Wang , Cynthia Rudin , Alberto Bartesaghi

Electron tomography is a powerful tool for understanding the morphology of materials in three dimensions, but conventional reconstruction algorithms typically suffer from missing-wedge artifacts and data misalignment imposed by experimental…

Image and Video Processing · Electrical Eng. & Systems 2025-12-10 Cedric Lim , Corneel Casert , Arthur R. C. McCray , Serin Lee , Andrew Barnum , Jennifer Dionne , Colin Ophus

Here we apply hyperspectral bright field imaging to collect computed tomographic images with excellent energy resolution (800 eV), applying it for the first time to map the distribution of stain in a fixed biological sample through its…

Significant progress has been made in spatial resolution using environmental transmission electron microscopes (ETEM), which now enables atomic resolution visualization of structural transformation under variable temperature and gas…

Materials Science · Physics 2015-06-18 Wenpei Gao , Jianbo Wu , Xiaofeng Zhang , Aram Yoon , J. Mabon , W. Swiech , W. L. Wilson , H. Yang , Jian-Min Zuo

Generating hyperspectral images (HSIs) from RGB images through spectral reconstruction can significantly reduce the cost of HSI acquisition. In this paper, we propose a Fractal-Based Recursive Spectral Reconstruction Network (FRN), which…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Ge Meng , Zhongnan Cai , Ruizhe Chen , Jingyan Tu , Yingying Wang , Yue Huang , Xinghao Ding

The equation of state (EOS) of dense nuclear matter is a key factor to determine the internal structure and properties of neutron stars. However, the EOS of high-density nuclear matter has great uncertainty mainly because the terrestrial…

Nuclear Theory · Physics 2023-12-27 Zehan Wu , Dehua Wen

Hyperspectral microscopy is an imaging technique that provides spectroscopic information with high spatial resolution. When applied in the relevant wavelength region, such as in the infrared (IR), it can reveal a rich spectral fingerprint…

Magnetic resonance spectroscopic imaging (SI) is a unique imaging technique that provides biochemical information from in vivo tissues. The 1H spectra acquired from several spatial regions are quantified to yield metabolite concentrations…

Medical Physics · Physics 2019-10-23 Zohaib Iqbal , Dan Nguyen , Gilbert Hangel , Stanislav Motyka , Wolfgang Bogner , Steve Jiang

Spectral imaging is an umbrella term for energy-resolved x-ray imaging in medicine. The technique makes use of the energy dependence of x-ray attenuation to either increase the contrast-to-noise ratio, or to provide quantitative image data…

Medical Physics · Physics 2021-01-05 Erik Fredenberg

Denoising is a crucial step for hyperspectral image (HSI) applications. Though witnessing the great power of deep learning, existing HSI denoising methods suffer from limitations in capturing the non-local self-similarity. Transformers have…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Miaoyu Li , Ji Liu , Ying Fu , Yulun Zhang , Dejing Dou

High energy electron radiography (HEER) is a promising tool for high energy density physics diagnostics, apart from other tools like X/{\gamma} ray shadowgraphy and high energy proton radiography. Impressive progresses have been made in…

We report resolution enhancement in scanning electron microscopy (SEM) images using a generative adversarial network. We demonstrate the veracity of this deep learning-based super-resolution technique by inferring unresolved features in…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Kevin de Haan , Zachary S. Ballard , Yair Rivenson , Yichen Wu , Aydogan Ozcan

Intensity interferometry is a well known method in astronomy. Recently, a related method called incoherent diffractive imaging (IDI) was proposed to apply intensity correlations of x-ray fluorescence radiation to determine the 3D…

Optics · Physics 2020-08-27 Fabian Trost , Kartik Ayyer , Henry Chapman

We have developed a prototype time-resolved neutron imaging detector employing the micro-pixel chamber (muPIC), a micro-pattern gaseous detector, coupled with a field programmable gate array-based data acquisition system for applications in…

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

We present a data-enabled physics-informed neural network (DEPINN) with comprehensive numerical study for solving industrial scale neutron diffusion eigenvalue problems (NDEPs). In order to achieve an engineering acceptable accuracy for…

Computational Physics · Physics 2022-11-15 Yu Yang , Helin Gong , Shiquan Zhang , Qihong Yang , Zhang Chen , Qiaolin He , Qing Li

Decay energy spectrometry (DES) is a novel radiometric technique for high-precision analysis of nuclear materials. DES employs the unique thermal detection physics of cryogenic microcalorimeters with ultra-high energy resolution and 100$\%$…

Coherent diffractive imaging has enabled the structural analysis of individual free nanoparticles in a single shot and offers the tracking of their light induced dynamics with unprecedented spatial and temporal resolution. The retrieval of…

Optics · Physics 2020-05-07 Björn Kruse , Benjamin Liewehr , Christian Peltz , Thomas Fennel

Conventional ultrasound imaging relies on the computation of geometric time delay from multiple sensors to detect the position of a scatterer. In this paper, we present Ergodic Relay Ultrasound Imaging (ERUI), a method that utilizes an…

Ultrafast scattering using X-rays or electrons is an emerging method to obtain structure dynamics at the atomic length and time scales. However, directly resolving in real-space atomic motions is inherently limited by the finite detector…

Atomic Physics · Physics 2023-02-09 Adi Natan
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