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Selective classification is a powerful tool for automated decision-making in high-risk scenarios, allowing classifiers to act only when confident and abstain when uncertainty is high. Given a target accuracy, our goal is to minimize…

Statistics Theory · Mathematics 2025-10-28 Mohamed Ndaoud , Peter Radchenko , Bradley Rava

Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…

Statistics Theory · Mathematics 2007-06-13 Kathryn Roeder , Bernie Devlin , Larry Wasserman

We propose a novel infection spread model based on a random connection graph which represents connections between $n$ individuals. Infection spreads via connections between individuals and this results in a probabilistic cluster formation…

Information Theory · Computer Science 2022-03-30 Batuhan Arasli , Sennur Ulukus

Group testing is a method of identifying infected patients by performing tests on a pool of specimens collected from patients. For the case in which the test returns a false result with finite probability, we propose Bayesian inference and…

Machine Learning · Statistics 2020-07-15 Ayaka Sakata

Recent advances in deep learning have made the use of large, deep neural networks with tens of millions of parameters. The sheer size of these networks imposes a challenging computational burden during inference. Existing work focuses…

Machine Learning · Computer Science 2021-05-11 Weixin Liang , James Zou

In clinical trials, there is potential to improve precision and reduce the required sample size by appropriately adjusting for baseline variables in the statistical analysis. This is called covariate adjustment. Despite recommendations by…

Methodology · Statistics 2022-06-20 Kelly Van Lancker , Joshua Betz , Michael Rosenblum

Bayesian Optimal Experimental Design (BOED) is a powerful tool to reduce the cost of running a sequence of experiments. When based on the Expected Information Gain (EIG), design optimization corresponds to the maximization of some…

Machine Learning · Statistics 2025-03-14 Jacopo Iollo , Christophe Heinkelé , Pierre Alliez , Florence Forbes

Detection of defective members of large populations has been widely studied in the statistics community under the name "group testing", a problem which dates back to World War II when it was suggested for syphilis screening. There the main…

Information Theory · Computer Science 2009-09-28 Mahdi Cheraghchi , Ali Hormati , Amin Karbasi , Martin Vetterli

Bayesian experimental design (BED) is a framework that uses statistical models and decision making under uncertainty to optimise the cost and performance of a scientific experiment. Sequential BED, as opposed to static BED, considers the…

Machine Learning · Statistics 2020-03-23 Steven Kleinegesse , Christopher Drovandi , Michael U. Gutmann

Computerized adaptive testing (CAT) is an interesting and promising approach to testing human abilities. In our research we use Bayesian networks to create a model of tested humans. We collected data from paper tests performed with grammar…

Artificial Intelligence · Computer Science 2017-03-28 Martin Plajner , Jiří Vomlel

Group testing (GT) is the art of identifying binary signals and the marketplace for exchanging new ideas for related fields such as unique-element counting, compressed sensing, traitor tracing, and geno-typing. A GT scheme can be…

Information Theory · Computer Science 2024-05-28 Hsin-Po Wang , Venkatesan Guruswami

In the experimental design literature, Neyman allocation refers to the practice of allocating units into treated and control groups, potentially in unequal numbers proportional to their respective standard deviations, with the objective of…

Methodology · Statistics 2026-01-15 Jinglong Zhao

In this paper, we study the problem of non-adaptive group testing, in which one seeks to identify which items are defective given a set of suitably-designed tests whose outcomes indicate whether or not at least one defective item was…

Information Theory · Computer Science 2025-09-26 Lan V. Truong , Matthew Aldridge , Jonathan Scarlett

We consider nonadaptive probabilistic group testing in the linear regime, where each of n items is defective independently with probability p in (0,1), and p is a constant independent of n. We show that testing each item individually is…

Information Theory · Computer Science 2025-09-26 Matthew Aldridge

Bayesian adaptive designs have gained popularity in all phases of clinical trials with numerous new developments in the past few decades. During the COVID-19 pandemic, the need to establish evidence for the effectiveness of vaccines,…

Methodology · Statistics 2022-03-08 Shirin Golchi

Machine learning models are routinely used to support decisions that affect individuals -- be it to screen a patient for a serious illness or to gauge their response to treatment. In these tasks, we are limited to learning models from…

Machine Learning · Computer Science 2025-06-10 Sujay Nagaraj , Yang Liu , Flavio P. Calmon , Berk Ustun

Bayesian adaptive experimental design is a form of active learning, which chooses samples to maximize the information they give about uncertain parameters. Prior work has shown that other forms of active learning can suffer from active…

It is generally appreciated that a frequentist analysis of a group sequential trial must in order to avoid inflating type I error account for the fact that one or more interim analyses were performed. It is also to a lesser extent realised…

Methodology · Statistics 2025-12-12 Simon Bang Kristensen , Erik Thorlund Parner

Testing is recommended for all close contacts of confirmed COVID-19 patients. However, existing group testing methods are oblivious to the circumstances of contagion provided by contact tracing. Here, we build upon a well-known…

Applications · Statistics 2021-07-01 Stratis Tsirtsis , Abir De , Lars Lorch , Manuel Gomez-Rodriguez

A new approach to adaptive design of clinical trials is proposed in a general multiparameter exponential family setting, based on generalized likelihood ratio statistics and optimal sequential testing theory. These designs are easy to…

Statistics Theory · Mathematics 2011-05-25 Jay Bartroff , Tze Leung Lai