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Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

Multiple stains are usually used to highlight biological substances in biomedical image analysis. To decompose multiple stains for co-localization quantification, blind source separation is usually performed. Prior model-based stain…

Image and Video Processing · Electrical Eng. & Systems 2021-02-16 Xingyu Li

Automated skin lesion classification using deep learning has shown remarkable accuracy, yet clinical adoption remains limited due to the "black box" nature of these models. We present MelanomaNet, an explainable deep learning system for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Sukhrobbek Ilyosbekov

Gastrointestinal (GI) imaging via Wireless Capsule Endoscopy (WCE) generates a large number of images requiring manual screening. Deep learning-based Clinical Decision Support (CDS) systems can assist screening, yet their performance relies…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Dimitrios E. Diamantis , Dimitris K. Iakovidis

The identification and quantification of markers in medical images is critical for diagnosis, prognosis and management of patients in clinical practice. Supervised- or weakly supervised training enables the detection of findings that are…

The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed

Latent diffusion models have established a new state-of-the-art in high-resolution visual generation. Integrating Vision Foundation Model priors improves generative efficiency, yet existing latent designs remain largely heuristic. These…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Hangyu Liu , Jianyong Wang , Yutao Sun

Vision disorders significantly impact millions of lives, altering how visual information is processed and perceived. In this work, a computational framework was developed using the BrokenEyes system to simulate five common eye disorders:…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Prottay Kumar Adhikary

DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…

Quantitative Methods · Quantitative Biology 2025-10-17 Pierre Fayolle , Alexandre Bône , Noëlie Debs , Mathieu Naudin , Pascal Bourdon , Remy Guillevin , David Helbert

Deep learning implemented with convolutional network architectures can exceed specialists' diagnostic accuracy. However, whole-image deep learning trained on a given dataset may not generalize to other datasets. The problem arises because…

Computer Vision and Pattern Recognition · Computer Science 2023-05-17 Norsang Lama , R. Joe Stanley , Anand Nambisan , Akanksha Maurya , Jason Hagerty , William V. Stoecker

Advancements in deep generative models such as generative adversarial networks and variational autoencoders have resulted in the ability to generate realistic images that are visually indistinguishable from real images, which raises…

Image and Video Processing · Electrical Eng. & Systems 2021-02-16 Tarik Dzanic , Karan Shah , Freddie Witherden

Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME) are the major causes of vision loss in developed countries. Alteration of retinal layer structure and appearance of exudate are the most significant signs of these…

Image and Video Processing · Electrical Eng. & Systems 2019-03-19 Elahe Mousavi , Rahele Kafieh , Hossein Rabbani

Age related macular degeneration (AMD) is one of the major causes for blindness in the elderly population. In this report, we propose deep learning based methods for retinal analysis using color fundus images for computer aided diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-04 Sharath M Shankaranarayana

Glaucoma is a chronic eye disease that leads to irreversible vision loss. The cup to disc ratio (CDR) plays an important role in the screening and diagnosis of glaucoma. Thus, the accurate and automatic segmentation of optic disc (OD) and…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Huazhu Fu , Jun Cheng , Yanwu Xu , Damon Wing Kee Wong , Jiang Liu , Xiaochun Cao

Differential medical VQA models compare multiple images to identify clinically meaningful changes and rely on vision encoders to capture fine-grained visual differences that reflect radiologists' comparative diagnostic workflows. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Denis Musinguzi , Caren Han , Prasenjit Mitra

Glaucoma is one of the leading causes of irreversible blindness. Segmentation of optic disc (OD) and optic cup (OC) on fundus images is a crucial step in glaucoma screening. Although many deep learning models have been constructed for this…

Image and Video Processing · Electrical Eng. & Systems 2023-04-11 Ziyang Chen , Yongsheng Pan , Yong Xia

Diabetic Retinopathy (DR) is a constantly deteriorating disease, being one of the leading causes of vision impairment and blindness. Subtle distinction among different grades and existence of many significant small features make the task of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Sheikh Muhammad Saiful Islam , Md Mahedi Hasan , Sohaib Abdullah

Multi-modal medical image segmentation plays an essential role in clinical diagnosis. It remains challenging as the input modalities are often not well-aligned spatially. Existing learning-based methods mainly consider sharing trainable…

Computer Vision and Pattern Recognition · Computer Science 2021-01-06 Jingkun Chen , Wenqi Li , Hongwei Li , Jianguo Zhang

Deep learning-based segmentation methods have been widely employed for automatic glaucoma diagnosis and prognosis. In practice, fundus images obtained by different fundus cameras vary significantly in terms of illumination and intensity.…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Qianbi Yu , Dongnan Liu , Chaoyi Zhang , Xinwen Zhang , Weidong Cai