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Brain functional connectivity (FC) reveals biomarkers for identification of various neuropsychiatric disorders. Recent application of deep neural networks (DNNs) to connectome-based classification mostly relies on traditional convolutional…

Neurons and Cognition · Quantitative Biology 2024-01-31 Fuad Noman , Chee-Ming Ting , Hakmook Kang , Raphael C. -W. Phan , Brian D. Boyd , Warren D. Taylor , Hernando Ombao

Glaucoma is a prevalent eye disease that progresses silently without symptoms. If not detected and treated early, it can cause permanent vision loss. Computer-assisted diagnosis systems play a crucial role in timely and efficient…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Mustafa Yurdakul , Kubra Uyar , Sakir Tasdemir

Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of preventable blindness among working-age adults. Traditional approaches in the literature focus on standard color fundus photography (CFP) for the detection of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Pablo Jimenez-Lizcano , Sergio Romero-Tapiador , Ruben Tolosana , Aythami Morales , Guillermo González de Rivera , Ruben Vera-Rodriguez , Julian Fierrez

Diagnosing glaucoma progression is critical for limiting irreversible vision loss. A common method for assessing glaucoma progression uses a longitudinal series of visual fields (VF) acquired at regular intervals. VF data are characterized…

Applications · Statistics 2018-05-31 Samuel I. Berchuck , Jean-Claude Mwanza , Joshua L. Warren

Reliable detection of retinal diseases from fundus images is challenged by the variability in imaging quality, subtle early-stage manifestations, and domain shift across datasets. In this study, we systematically evaluated a Vision…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Jan Benedikt Ruhland , Thorsten Papenbrock , Jan-Peter Sowa , Ali Canbay , Nicole Eter , Bernd Freisleben , Dominik Heider

Diabetic eye disease is one of the fastest growing causes of preventable blindness. With the advent of anti-VEGF (vascular endothelial growth factor) therapies, it has become increasingly important to detect center-involved diabetic macular…

Here, we examine the latest advances in glaucoma detection through Deep Learning (DL) algorithms using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This study focuses on three aspects of DL-based glaucoma…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Mahtab Faraji , Homa Rashidisabet , George R. Nahass , RV Paul Chan , Thasarat S Vajaranant , Darvin Yi

Purpose: (1) To develop a deep learning algorithm to automatically segment structures of the optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) scans; (2) To assess whether 3D macula or ONH structures (or…

Glaucoma is a common eye disease that leads to irreversible blindness unless timely detected. Hence, glaucoma detection at an early stage is of utmost importance for a better treatment plan and ultimately saving the vision. The recent…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Dipankar Das , Deepak Ranjan Nayak

Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Xi Wang , Hao Chen , Luyang Luo , An-ran Ran , Poemen P. Chan , Clement C. Tham , Carol Y. Cheung , Pheng-Ann Heng

Segmentation of blood vessels in retinal images provides early diagnosis of diseases like glaucoma, diabetic retinopathy and macular degeneration. Among these diseases occurrence of Glaucoma is most frequent and has serious ocular…

Computer Vision and Pattern Recognition · Computer Science 2012-09-07 Nilanjan Dey , Anamitra Bardhan Roy , Moumita Pal , Achintya Das

Convolutional Neural Network models have successfully detected retinal illness from optical coherence tomography (OCT) and fundus images. These CNN models frequently rely on vast amounts of labeled data for training, difficult to obtain,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Sourya Dipta Das , Saikat Dutta , Nisarg A. Shah , Dwarikanath Mahapatra , Zongyuan Ge

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Yupeng Zhang , Adam G. Dunn , Usman Naseem , Jinman Kim

The estimation of glaucoma progression is a challenging task as the rate of disease progression varies among individuals in addition to other factors such as measurement variability and the lack of standardization in defining progression.…

Diabetic retinopathy and diabetic macular edema are significant complications of diabetes that can lead to vision loss. Early detection through ultra-widefield fundus imaging enhances patient outcomes but presents challenges in image…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Philippe Zhang , Pierre-Henri Conze , Mathieu Lamard , Gwenolé Quellec , Mostafa El Habib Daho

Fairness (also known as equity interchangeably) in machine learning is important for societal well-being, but limited public datasets hinder its progress. Currently, no dedicated public medical datasets with imaging data for fairness…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Yan Luo , Yu Tian , Min Shi , Louis R. Pasquale , Lucy Q. Shen , Nazlee Zebardast , Tobias Elze , Mengyu Wang

The utilization of longitudinal datasets for glaucoma progression prediction offers a compelling approach to support early therapeutic interventions. Predominant methodologies in this domain have primarily focused on the direct prediction…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zhihao Zhao , Junjie Yang , Shahrooz Faghihroohi , Yinzheng Zhao , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

The Bayesian approach has become increasingly popular because it allows to model quite complex models via Markov chain Monte Carlo (MCMC) sampling. However, it is also recognized nowadays that MCMC sampling can become computationally…

Automated segmentation of retinal blood vessels in label-free fundus images entails a pivotal role in computed aided diagnosis of ophthalmic pathologies, viz., diabetic retinopathy, hypertensive disorders and cardiovascular diseases. The…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Avisek Lahiri , Abhijit Guha Roy , Debdoot Sheet , Prabir Kumar Biswas