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While the SARS-CoV-2 keeps spreading world-wide, comparing its evolution across different nations is a timely challenge of both theoretical and practical importance. The large variety of dissimilar and country-dependent epidemiological…

During the COVID-19 pandemic, community containment measures have been implemented in different parts of the world. However, despite government recommendations and mandates, a progressive increase in mobility was observed in several sites.…

Physics and Society · Physics 2021-03-29 Ariel Félix Gualtieri , Pedro Hecht

The present paper introduces a new model used to study and analyse the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) epidemic-reported-data from Spain. This is a Hidden Markov Model whose hidden layer is a regeneration process…

In this article, we propose a theory to explain the reduction in vaccine effectiveness (VE) against the Delta SARS-CoV-2 variant and decreasing VE over time reported in recent studies. Using a model illustration, we show that in-host viral…

Populations and Evolution · Quantitative Biology 2021-12-09 Wan Yang , Jeffrey Shaman

Wastewater based epidemiology is recognized as one of the monitoring pillars, providing essential information for pandemic management. Central in the methodology are data modelling concepts for both communicating the monitoring results but…

Applications · Statistics 2022-08-30 Wolfgang Rauch , Hannes Schenk , Heribert Insam , Rudolf Markt , Norbert Kreuzinger

The SARS-CoV-2 coronavirus is the cause of the COVID-19 disease in humans. Like many coronaviruses, it can adapt to different hosts and evolve into different lineages. It is well-known that the major SARS-CoV-2 lineages are characterized by…

Machine Learning · Computer Science 2022-11-23 Sarwan Ali

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

The COVID-19 outbreak is asynchronous in US counties. Mitigating the COVID-19 transmission requires not only the state and federal level order of protective measures such as social distancing and testing, but also public awareness of…

Applications · Statistics 2021-05-03 Hanmo Li , Mengyang Gu

COVID-19 is a devastating respiratory and inflammatory illness caused by a new coronavirus that is rapidly spreading throughout the human population. Over the past 6 months, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the…

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spurred unprecedented and concerted worldwide research to curtail and eradicate this pathogen. SARS-CoV-2 has four structural proteins:…

Biological Physics · Physics 2022-09-26 Siyu Li , Roya Zandi

With the global spread and increasing transmission rate of SARS-CoV-2, more and more laboratories and researchers are turning their attention to wastewater-based epidemiology (WBE), hoping it can become an effective tool for large-scale…

With the present highly infectious dominant SARS-CoV-2 strain of B1.1.529 or Omicron spreading around the globe, there is concern that the COVID-19 pandemic will not end soon and that it will be a race against time until a more contagious…

Populations and Evolution · Quantitative Biology 2022-04-26 Chottiwatt Jittprasong

Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause of the pandemic COVID-19. Early symptoms overlap with other common conditions such as common cold and Influenza, making early screening and diagnosis are…

COVID-19 has shown a relatively low mortality rate in young healthy individuals, with the majority of this group being asymptomatic or having mild symptoms, while the severity of the disease among individuals with underlying health…

Physics and Society · Physics 2020-06-22 Dario Ortega Anderez , Eiman Kanjo , Ganna Pogrebna , Shane Johnson , John Alan Hunt

The usual development cycles are too slow for the development of vaccines, diagnostics and treatments in pandemics such as the ongoing SARS-CoV-2 pandemic. Given the pressure in such a situation, there is a risk that findings of early…

Applications · Statistics 2020-10-12 Sarah Friedrich , Tim Friede

In this work, we developed a deep learning model-based approach to forecast the spreading trend of SARS-CoV-2 in the United States. We implemented the designed model using the United States to confirm cases and state demographic data and…

Computers and Society · Computer Science 2020-08-14 Tong Yang , Long Sha , Justin Li , Pengyu Hong

We are currently facing a highly critical case of a world-wide pandemic. The novel coronavirus (SARS-CoV-2, a.k.a. COVID-19) has proved to be extremely contagious and the original outbreak from Asia has now spread to all continents. This…

Physics and Society · Physics 2020-06-26 Priyanka , Vicky Verma

The coronavirus pandemic has rapidly evolved into an unprecedented crisis. The susceptible-infectious-removed (SIR) model and its variants have been used for modeling the pandemic. However, time-independent parameters in the classical…

Populations and Evolution · Quantitative Biology 2020-09-09 Hyokyoung G. Hong , Yi Li

Combating the SARS-CoV2 pandemic will require the fast development of effective preventive vaccines. Regulatory agencies may open accelerated approval pathways for vaccines if an immunological marker can be established as a mediator of a…

Methodology · Statistics 2021-03-05 David Benkeser , Iván Díaz , Jialu Ran

Sequential Monte Carlo (SMC) methods are widely used to draw samples from intractable target distributions. Particle degeneracy can hinder the use of SMC when the target distribution is highly constrained or multimodal. As a motivating…

Methodology · Statistics 2022-10-26 Zhaoran Hou , Samuel W. K. Wong
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