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Automated nodule segmentation is essential for computer-assisted diagnosis in ultrasound images. Nevertheless, most existing methods depend on precise pixel-level annotations by medical professionals, a process that is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Xingyue Zhao , Peiqi Li , Xiangde Luo , Meng Yang , Shi Chang , Zhongyu Li

Weakly supervised segmentation requires assigning a label to every pixel based on training instances with partial annotations such as image-level tags, object bounding boxes, labeled points and scribbles. This task is challenging, as coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Tsung-Wei Ke , Jyh-Jing Hwang , Stella X. Yu

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Since the labelling for the positive images/videos is ambiguous in weakly supervised segment annotation, negative mining based methods that only use the intra-class information emerge. In these methods, negative instances are utilized to…

Computer Vision and Pattern Recognition · Computer Science 2018-12-18 Liantao Wang , Qingwu Li , Jianfeng Lu

Weakly supervised object detection (WSOD) is a challenging task when provided with image category supervision but required to simultaneously learn object locations and object detectors. Many WSOD approaches adopt multiple instance learning…

Computer Vision and Pattern Recognition · Computer Science 2019-04-12 Fang Wan , Chang Liu , Wei Ke , Xiangyang Ji , Jianbin Jiao , Qixiang Ye

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Deep learning has achieved remarkable success in medicalimage segmentation, but it usually requires a large numberof images labeled with fine-grained segmentation masks, andthe annotation of these masks can be very expensive…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Yanwu Xu , Mingming Gong , Shaoan Xie , Kayhan Batmanghelich

We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…

Multiple Instance Learning (MIL) involves predicting a single label for a bag of instances, given positive or negative labels at bag-level, without accessing to label for each instance in the training phase. Since a positive bag contains…

Machine Learning · Computer Science 2020-09-09 Beomjo Shin , Junsu Cho , Hwanjo Yu , Seungjin Choi

Multiple instance learning (MIL) problem is currently solved from either bag-classification or instance-classification perspective, both of which ignore important information contained in some instances and result in limited performance.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Yingfan Ma , Xiaoyuan Luo , Mingzhi Yuan , Xinrong Chen , Manning Wang

Despite the availability of a huge amount of video data accompanied by descriptive texts, it is not always easy to exploit the information contained in natural language in order to automatically recognize video concepts. Towards this goal,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Giorgos Bouritsas , Petros Koutras , Athanasia Zlatintsi , Petros Maragos

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Weakly supervised whole slide image (WSI) classification is challenging due to the lack of patch-level labels and high computational costs. State-of-the-art methods use self-supervised patch-wise feature representations for multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Wentao Huang , Xiaoling Hu , Shahira Abousamra , Prateek Prasanna , Chao Chen

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

The whole slide image (WSI) classification is often formulated as a multiple instance learning (MIL) problem. Since the positive tissue is only a small fraction of the gigapixel WSI, existing MIL methods intuitively focus on identifying…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenhao Tang , Sheng Huang , Xiaoxian Zhang , Fengtao Zhou , Yi Zhang , Bo Liu

Semantic labelling and instance segmentation are two tasks that require particularly costly annotations. Starting from weak supervision in the form of bounding box detection annotations, we propose a new approach that does not require…

Computer Vision and Pattern Recognition · Computer Science 2016-11-24 Anna Khoreva , Rodrigo Benenson , Jan Hosang , Matthias Hein , Bernt Schiele

Multiple instance learning (MIL) is the preferred approach for whole slide image classification. However, most MIL approaches do not exploit the interdependencies of tiles extracted from a whole slide image, which could provide valuable…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Marvin Lerousseau , Maria Vakalopoulou , Eric Deutsch , Nikos Paragios

Recent leading approaches to semantic segmentation rely on deep convolutional networks trained with human-annotated, pixel-level segmentation masks. Such pixel-accurate supervision demands expensive labeling effort and limits the…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Jifeng Dai , Kaiming He , Jian Sun

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

In Multiple Instance learning (MIL), weak labels are provided at the bag level with only presence/absence information known. However, there is a considerable gap in performance in comparison to a fully supervised model, limiting the…

Machine Learning · Computer Science 2021-03-22 Anxiang Zhang , Ankit Shah , Bhiksha Raj