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In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

Learning classifiers using skewed or imbalanced datasets can occasionally lead to classification issues; this is a serious issue. In some cases, one class contains the majority of examples while the other, which is frequently the more…

Machine Learning · Computer Science 2022-11-11 Satyendra Singh Rawat , Amit Kumar Mishra

With the rapid growth of memory and computing power, datasets are becoming increasingly complex and imbalanced. This is especially severe in the context of clinical data, where there may be one rare event for many cases in the majority…

Accurate and reliable probability predictions are essential for multi-class supervised learning tasks, where well-calibrated models enable rational decision-making. While isotonic regression has proven effective for binary calibration, its…

Machine Learning · Computer Science 2025-12-11 Alon Arad , Saharon Rosset

Class imbalance poses a significant challenge in classification tasks, where traditional approaches often lead to biased models and unreliable predictions. Undersampling and oversampling techniques have been commonly employed to address…

Machine Learning · Computer Science 2025-10-22 Matt Clifford , Jonathan Erskine , Alexander Hepburn , Raúl Santos-Rodríguez , Dario Garcia-Garcia

Deep learning techniques have revolutionised medical imaging, improving diagnostic accuracy and enabling both more accurate and earlier disease detection. However, the relationship between pre-training strategies and downstream performance…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Felix Krones

Optimal decision making requires that classifiers produce uncertainty estimates consistent with their empirical accuracy. However, deep neural networks are often under- or over-confident in their predictions. Consequently, methods have been…

Data-sparse settings such as robotic manipulation, molecular physics, and galaxy morphology classification are some of the hardest domains for deep learning. For these problems, equivariant networks can help improve modeling across…

Machine Learning · Computer Science 2026-01-30 Edward Berman , Jacob Ginesin , Marco Pacini , Robin Walters

The confidence calibration of deep learning-based perception models plays a crucial role in their reliability. Especially in the context of autonomous driving, downstream tasks like prediction and planning depend on accurate confidence…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Mariella Dreissig , Florian Piewak , Joschka Boedecker

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

Machine Learning · Computer Science 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

Testing of deep learning models is challenging due to the excessive number and complexity of computations involved. As a result, test data selection is performed manually and in an ad hoc way. This raises the question of how we can…

Machine Learning · Computer Science 2019-05-01 Wei Ma , Mike Papadakis , Anestis Tsakmalis , Maxime Cordy , Yves Le Traon

Weakly supervised learning with noisy data has drawn attention in the medical imaging community due to the sparsity of high-quality disease labels. However, little is known about the limitations of such weakly supervised learning and the…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Fakrul Islam Tushar , Vincent M. D'Anniballe , Geoffrey D. Rubin , Joseph Y. Lo

Fine-tuning is arguably the most straightforward way to tailor a pre-trained model (e.g., a foundation model) to downstream applications, but it also comes with the risk of losing valuable knowledge the model had learned in pre-training.…

Calibration is a fundamental property of a good predictive model: it requires that the model predicts correctly in proportion to its confidence. Modern neural networks, however, provide no strong guarantees on their calibration -- and can…

Machine Learning · Computer Science 2022-10-07 A. Michael Carrell , Neil Mallinar , James Lucas , Preetum Nakkiran

Medical images can be used to predict a clinical score coding for the severity of a disease, a pain level or the complexity of a cognitive task. In all these cases, the predicted variable has a natural order. While a standard classifier…

Machine Learning · Computer Science 2012-10-02 Fabian Pedregosa , Alexandre Gramfort , Gaël Varoquaux , Elodie Cauvet , Christophe Pallier , Bertrand Thirion

The integration of artificial intelligence into clinical workflows requires reliable and robust models. Repeatability is a key attribute of model robustness. Repeatable models output predictions with low variation during independent tests…

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kai Han , Chongwen Lyu , Lele Ma , Chengxuan Qian , Siqi Ma , Zheng Pang , Jun Chen , Zhe Liu

Estimating the prevalence of a category in a population using imperfect measurement devices (diagnostic tests, classifiers, or large language models) is fundamental to science, public health, and online trust and safety. Standard approaches…

Artificial Intelligence · Computer Science 2026-04-24 Fridolin Linder , Thomas Leeper , Daniel Haimovich , Niek Tax , Lorenzo Perini , Milan Vojnovic

With the development of deep learning, medical image classification has been significantly improved. However, deep learning requires massive data with labels. While labeling the samples by human experts is expensive and time-consuming,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Jiarun Liu , Ruirui Li , Chuan Sun

Imaging techniques such as Chest X-rays, whole slide images, and optical coherence tomography serve as the initial screening and detection for a wide variety of medical pulmonary and ophthalmic conditions respectively. This paper…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Jutika Borah , Kumaresh Sarmah , Hidam Kumarjit Singh