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The human brain is a complex network that supports mental function. The nascent field of network neuroscience applies tools from mathematics to neuroimaging data in the hopes of shedding light on cognitive function. A critical question…

Neurons and Cognition · Quantitative Biology 2017-04-26 John D. Medaglia , Perry Zurn , Walter Sinnott-Armstrong , Danielle S. Bassett

Reversibility is a key issue in the interface between computation and physics, and of growing importance as miniaturization progresses towards its physical limits. Most foundational work on reversible computing to date has focussed on…

Logic in Computer Science · Computer Science 2011-12-01 Samson Abramsky

A sufficiently large information flux in recurrent neural networks, quantified by the mutual information between successive network states, is considered a prerequisite for rich information processing capabilities. This raises the question…

Neurons and Cognition · Quantitative Biology 2026-05-15 Claus Metzner , Ali Ghebleh , Karin Prebeck , Achim Schilling , Andreas Maier , Thomas Kinfe , Patrick Krauss

Reverse engineering (RE) in Integrated Circuits (IC) is a process in which one will attempt to extract the internals of an IC, extract the circuit structure, and determine the gate-level information of an IC. In general, RE process can be…

Inhibition is one of the core concepts in Cognitive Psychology. The idea of inhibitory mechanisms actively weakening representations in the human mind has inspired a great number of studies in various research domains. In contrast, Computer…

Artificial Intelligence · Computer Science 2019-12-03 Tobias Tempel , Claudia Niederée , Christian Jilek , Andrea Ceroni , Heiko Maus , Yannick Runge , Christian Frings

Minimization of cortical prediction errors has been considered a key computational goal of the cerebral cortex underlying perception, action and learning. However, it is still unclear how the cortex should form and use information about…

Neurons and Cognition · Quantitative Biology 2025-04-07 Arno Granier , Mihai A. Petrovici , Walter Senn , Katharina A. Wilmes

Neuromorphic engineering is a rapidly developing field that aims to take inspiration from the biological organization of neural systems to develop novel technology for computing, sensing, and actuating. The unique properties of such systems…

Systems and Control · Electrical Eng. & Systems 2022-01-26 Luka Ribar , Rodolphe Sepulchre

'If I cannot build it, I do not understand it.' So said Nobel laureate Richard Feynman, and by his metric, we understand a bit about physics, less about chemistry, and almost nothing about biology. When we fully understand a phenomenon, we…

Neurons and Cognition · Quantitative Biology 2017-04-13 Richard Granger

Neuroengineering is faced with unique challenges in repairing or replacing complex neural systems that are composed of many interacting parts. These interactions form intricate patterns over large spatiotemporal scales, and produce emergent…

Neurons and Cognition · Quantitative Biology 2016-12-26 Danielle S. Bassett , Ankit N. Khambhati , Scott T. Grafton

In the last decades, great achievements have been made in the development of computing machines. However, due to exponential growth of transistor density and in particular due to tremendously increasing power consumption, researchers expect…

Emerging Technologies · Computer Science 2014-07-03 Piyush Gautam

We propose a neural information processing system which is obtained by re-purposing the function of a biological neural circuit model, to govern simulated and real-world control tasks. Inspired by the structure of the nervous system of the…

Machine Learning · Computer Science 2019-11-21 Ramin Hasani , Mathias Lechner , Alexander Amini , Daniela Rus , Radu Grosu

Biological visual systems exhibit abundant recurrent connectivity. State-of-the-art neural network models for visual recognition, by contrast, rely heavily or exclusively on feedforward computation. Any finite-time recurrent neural network…

Neurons and Cognition · Quantitative Biology 2020-12-09 Ruben S. van Bergen , Nikolaus Kriegeskorte

Since underlying hardware components form the basis of trust in virtually any computing system, security failures in hardware pose a devastating threat to our daily lives. Hardware reverse engineering is commonly employed by security…

Cryptography and Security · Computer Science 2019-10-02 Carina Wiesen , Steffen Becker , Marc Fyrbiak , Nils Albartus , Malte Elson , Nikol Rummel , Christof Paar

Connecting neural activity to function is a common aim in neuroscience. How to define and conceptualize function, however, can vary. Here I focus on grounding this goal in the specific question of how a given change in behavior is produced…

Neurons and Cognition · Quantitative Biology 2023-11-14 Grace W. Lindsay

As machine learning is increasingly used to inform consequential decision-making (e.g., pre-trial bail and loan approval), it becomes important to explain how the system arrived at its decision, and also suggest actions to achieve a…

Machine Learning · Computer Science 2020-10-09 Amir-Hossein Karimi , Bernhard Schölkopf , Isabel Valera

Neuroscience has focused on the detailed implementation of computation, studying neural codes, dynamics and circuits. In machine learning, however, artificial neural networks tend to eschew precisely designed codes, dynamics or circuits in…

Neurons and Cognition · Quantitative Biology 2020-02-04 Adam Marblestone , Greg Wayne , Konrad Kording

Efficient coding theory posits that sensory circuits transform natural signals into neural representations that maximize information transmission subject to resource constraints. Local interneurons are thought to play an important role in…

Neurons and Cognition · Quantitative Biology 2025-01-22 David Lipshutz , Eero P. Simoncelli

Mechanistic interpretability aims to explain neural model behaviour by reverse-engineering learned computational structure into human-understandable components. Without a formal framework, however, mechanistic explanations cannot be…

Machine Learning · Computer Science 2026-05-12 Ward Gauderis , Thomas Dooms , Steven T. Holmer , Kola Ayonrinde , Geraint A. Wiggins

Recurrent neural networks (RNNs) are a widely used tool for modeling sequential data, yet they are often treated as inscrutable black boxes. Given a trained recurrent network, we would like to reverse engineer it--to obtain a quantitative,…

Machine Learning · Computer Science 2019-12-06 Niru Maheswaranathan , Alex Williams , Matthew D. Golub , Surya Ganguli , David Sussillo