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Related papers: Characterizing SARS-CoV-2 Spike Sequences Based on…

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Genomic surveillance of infectious diseases allows monitoring circulating and emerging variants and quantifying their epidemic potential. However, due to the high costs associated with genomic sequencing, only a limited number of samples…

Characterising drivers of SARS-CoV-2 circulation is crucial for understanding COVID-19 because of the severity of control measures adopted during the pandemic. Whole genome sequence data augmented with demographic metadata provides the best…

Populations and Evolution · Quantitative Biology 2024-09-17 Anna Gamża , Samantha Lycett , Will Harvey , Joseph Hughes , Sema Nickbakhsh , David L Robertson , Alison Smith Palmer , Anthony Wood , Rowland Kao

In the past several months, COVID-19 has spread over the globe and caused severe damage to the people and the society. In the context of this severe situation, an effective drug discovery method to generate potential drugs is extremely…

Machine Learning · Computer Science 2021-04-26 Tianyue Cheng , Tianchi Fan , Landi Wang

COVID-19 pandemic, is still unknown and is an important open question. There are speculations that bats are a possible origin. Likewise, there are many closely related (corona-) viruses, such as SARS, which was found to be transmitted…

Genomics · Quantitative Biology 2022-01-10 Sarwan Ali , Babatunde Bello , Prakash Chourasia , Ria Thazhe Punathil , Yijing Zhou , Murray Patterson

SARS-CoV-2 has characteristics of wide contagion and quick propagation velocity. To analyse the visual information of it, we build a SARS-CoV-2 Microscopic Image Dataset (SC2-MID) with 48 electron microscopic images and also prepare their…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Chen Li , Jiawei Zhang , Frank Kulwa , Shouliang Qi , Ziyu Qi

Mathematical models of SARS-CoV-2 spread are used for guiding the design of mitigation steps aimed at containing and decelerating the contagion, and at identifying impending breaches of health care system surge capacity. The challenges of…

Populations and Evolution · Quantitative Biology 2020-06-17 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

Proteins play a key role in facilitating the infectiousness of the 2019 novel coronavirus. A specific spike protein enables this virus to bind to human cells, and a thorough understanding of its 3-dimensional structure is therefore critical…

Biomolecules · Quantitative Biology 2020-10-28 Samuel W. K. Wong

During 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission has been increasing amongst the world's population at an alarming rate. Reducing the spread of SARS-CoV-2 and other diseases that are spread in…

Social and Information Networks · Computer Science 2022-03-22 Patrick Urrutia , David Wren , Chrysafis Vogiatzis , Ruriko Yoshida

In this work, we extend our previously developed compartmental SEIQRD model for SARS-CoV-2 in Belgium. We introduce SARS-CoV-2 variants of concern, vaccines, and seasonality in our model, as their addition has proven necessary for modelling…

Physics and Society · Physics 2024-01-12 Tijs W. Alleman , Michiel Rollier , Jenna Vergeynst , Jan M. Baetens

Background: Global viral threats underscore the need for effective genomic surveillance, but high costs and uneven resource distribution hamper its implementation. Targeting surveillance to international travelers in major travel hubs may…

Populations and Evolution · Quantitative Biology 2025-02-14 Haogao Gu , Jifan Li , Wanying Sun , Mengting Li , Kathy Leung , Joseph T. Wu , Hsiang-Yu Yuan , Maggie H. Wang , Bingyi Yang , Matthew R. McKay , Ning Ning , Leo L. M. Poon

Through the use of cutting-edge unsupervised classification techniques from statistics and machine learning, we characterise symptom phenotypes among symptomatic SARS-CoV-2 PCR-positive community cases. We first analyse each dataset in…

The COVID-19 pandemic has profoundly affected global health, driven by the remarkable transmissibility and mutational adaptability of the SARS-CoV-2 virus. Although five variants of concern, Alpha, Beta, Gamma, Delta, and Omicron, have been…

Genomics · Quantitative Biology 2026-05-07 Bo Jing , Kai-Rui Zhang , Hong-Li Zeng , Erik Aurell

The current SARS-CoV-2 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers. In this snapshot, our aim is to provide a…

Other Quantitative Biology · Quantitative Biology 2020-04-01 Yinon M. Bar-On , Avi I. Flamholz , Rob Phillips , Ron Milo

While the SARS-CoV-2 keeps spreading world-wide, comparing its evolution across different nations is a timely challenge of both theoretical and practical importance. The large variety of dissimilar and country-dependent epidemiological…

Although there is substantial literature on identifying structural changes for continuous spatio-temporal processes, the same is not true for categorical spatio-temporal data. This work bridges that gap and proposes a novel spatio-temporal…

Methodology · Statistics 2023-05-04 Siddharth Rawat , Abe Durrant , Adam Simpson , Grant Nielson , Candace Berrett , Soudeep Deb

The large-scale evolution of the SARS-CoV-2 virus has been marked by rapid turnover of genetic clades. New variants show intrinsic changes, notably increased transmissibility, as well as antigenic changes that reduce the cross-immunity…

Populations and Evolution · Quantitative Biology 2022-07-20 Matthijs Meijers , Denis Ruchnewitz , Marta Łuksza , Michael Lässig

In this work, we aim to study that the dynamics behavior for cumulative number of SARS-CoV-2 pandemic can provide information on the overall behavior of the spread over daily time.The cumulative data can be synthesized in an empirical form…

Populations and Evolution · Quantitative Biology 2020-11-16 Hamieh Mohamad , Doumit Mary , Toufaily Joumana , Hamieh Tayssir

Surges that have been observed at different periods in the number of COVID-19 cases are associated with the emergence of multiple SARS-CoV-2 (Severe Acute Respiratory Virus) variants. The design of methods to support laboratory detection…

In this paper, we propose a method to analyze correlations in pandemic-related data across different geographical regions, relying on the analysis of correlations for non-stationary time series, which are typical of pandemic data. Unlike…

Applications · Statistics 2026-04-06 Pablo Carlos López , Marcos Flores , Soham Biswas

Protein-protein interaction (PPI) networks have been used to investigate the influence of SARS-CoV-2 viral proteins on the function of human cells, laying out a deeper understanding of COVID--19 and providing ground for drug repurposing…

Biological Physics · Physics 2020-08-25 Arsham Ghavasieh , Sebastiano Bontorin , Oriol Artime , Manlio De Domenico