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Previous approaches using deep learning algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using spectral-domain…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Felipe A. Medeiros , Alessandro A. Jammal , Atalie C. Thompson

Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images…

Choroidal nevi are common benign pigmented lesions in the eye, with a small risk of transforming into melanoma. Early detection is critical to improving survival rates, but misdiagnosis or delayed diagnosis can lead to poor outcomes.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Mohammadmahdi Eshragh , Emad A. Mohammed , Behrouz Far , Ezekiel Weis , Carol L Shields , Sandor R Ferenczy , Trafford Crump

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Jiaxuan Li , Peiyao Jin , Jianfeng Zhu , Haidong Zou , Xun Xu , Min Tang , Minwen Zhou , Yu Gan , Jiangnan He , Yuye Ling , Yikai Su

Optic disk segmentation is a prerequisite step in automatic retinal screening systems. In this paper, we propose an algorithm for optic disk segmentation based on a local adaptive thresholding method. Location of the optic disk is validated…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Farnoosh Ghadiri , Robert Bergevin , Masoud Shafiee

Diabetic Retinopathy is the leading cause of blindness in the world. At least 90\% of new cases can be reduced with proper treatment and monitoring of the eyes. However, scanning the entire population of patients is a difficult endeavor.…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Sudharshan Chandra Babu , Shishira R Maiya , Sivasankar Elango

Observing retinal fundus images by an ophthalmologist is a major diagnosis approach for glaucoma. However, it is still difficult to distinguish the features of the lesion solely through manual observations, especially, in glaucoma early…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Peng Liu , Ruogu Fang

The segmentation of optic disc(OD) and optic cup(OC) from fundus images is an important fundamental task for glaucoma diagnosis. In the clinical practice, it is often necessary to collect opinions from multiple experts to obtain the final…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Junde Wu , Huihui Fang , Fangxin Shang , Zhaowei Wang , Dalu Yang , Wenshuo Zhou , Yehui Yang , Yanwu Xu

From diagnosing neovascular diseases to detecting white matter lesions, accurate tiny vessel segmentation in fundus images is critical. Promising results for accurate vessel segmentation have been known. However, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Suraj Mishra , Danny Z. Chen , X. Sharon Hu

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Accurate medical image segmentation requires effective modeling of both long-range dependencies and fine-grained boundary details. While transformers mitigate the issue of insufficient semantic information arising from the limited receptive…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Yanxin Li , Hui Wan , Libin Lan

Optical Coherence Tomography (OCT) is a widely used non-invasive imaging technique that provides detailed three-dimensional views of the retina, which are essential for the early and accurate diagnosis of ocular diseases. Consequently, OCT…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Huy Minh Nhat Nguyen , Triet Hoang Minh Dao , Chau Vinh Hoang Truong , Cuong Tuan Nguyen

Polyp segmentation is a critical step in colorectal cancer detection, yet it remains challenging due to the diverse shapes, sizes, and low contrast boundaries of polyps in medical imaging. In this work, we propose a novel framework that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Fatemeh Salahi Chashmi , Roya Sotoudeh

Diabetic retinopathy is the most important complication of diabetes. Early diagnosis of retinal lesions helps to avoid visual loss or blindness. Due to high-resolution and small-size lesion regions, applying existing methods, such as…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Zizheng Yan , Xiaoguang Han , Changmiao Wang , Yuda Qiu , Zixiang Xiong , Shuguang Cui

Medical Imaging is one of the growing fields in the world of computer vision. In this study, we aim to address the Diabetic Retinopathy (DR) problem as one of the open challenges in medical imaging. In this research, we propose a new lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-08-19 Farzan Shenavarmasouleh , Farid Ghareh Mohammadi , M. Hadi Amini , Thiab Taha , Khaled Rasheed , Hamid R. Arabnia

Recent advancements in image mixing and generative data augmentation have shown promise in enhancing image classification. However, these techniques face the challenge of balancing semantic fidelity with diversity. Specifically, image…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Ruoxin Chen , Zhe Wang , Ke-Yue Zhang , Shuang Wu , Jiamu Sun , Shouli Wang , Taiping Yao , Shouhong Ding

With the advancement of deep learning techniques, an increasing number of methods have been proposed for optic disc and cup (OD/OC) segmentation from the fundus images. Clinically, OD/OC segmentation is often annotated by multiple clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Junde Wu , Huihui Fang , Dalu Yang , Zhaowei Wang , Wenshuo Zhou , Fangxin Shang , Yehui Yang , Yanwu Xu

The Segment Anything Model (SAM) has gained popularity as a versatile image segmentation method, thanks to its strong generalization capabilities across various domains. However, when applied to optic disc (OD) and optic cup (OC)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Jinchen Yu , Yongwei Nie , Fei Qi , Wenxiong Liao , Hongmin Cai

Due to the difficulty in acquiring massive task-specific occluded images, the classification of occluded images with deep convolutional neural networks (CNNs) remains highly challenging. To alleviate the dependency on large-scale occluded…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Feng Cen , Xiaoyu Zhao , Wuzhuang Li , Guanghui Wang