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Enterprise information systems allow companies to maintain detailed records of their business process executions. These records can be extracted in the form of event logs, which capture the execution of activities across multiple instances…

Software Engineering · Computer Science 2021-05-14 Adriano Augusto , Marlon Dumas , Marcello La Rosa

Perception of auditory events is inherently multimodal relying on both audio and visual cues. A large number of existing multimodal approaches process each modality using modality-specific models and then fuse the embeddings to encode the…

Sound · Computer Science 2022-07-19 Amir Shirian , Krishna Somandepalli , Victor Sanchez , Tanaya Guha

Benefiting from the powerful expressive capability of graphs, graph-based approaches have been popularly applied to handle multi-modal medical data and achieved impressive performance in various biomedical applications. For disease…

Machine Learning · Computer Science 2022-03-14 Shuai Zheng , Zhenfeng Zhu , Zhizhe Liu , Zhenyu Guo , Yang Liu , Yuchen Yang , Yao Zhao

Progress in biomedical Named Entity Recognition (NER) and Entity Linking (EL) is currently hindered by a fragmented data landscape, a lack of resources for building explainable models, and the limitations of semantically-blind evaluation…

Computation and Language · Computer Science 2025-11-17 Nishant Mishra , Wilker Aziz , Iacer Calixto

Events describe the state changes of entities. In a document, multiple events are connected by various relations (e.g., Coreference, Temporal, Causal, and Subevent). Therefore, obtaining the connections between events through Event-Event…

Computation and Language · Computer Science 2024-03-20 Haochen Li , Di Geng

Diagnosing esophageal motility disorders pose significant challenges due to the complexity of high-resolution impedance manometry (HRIM) data and variability in clinical interpretation. This work explores the feasibility of a multimodal…

Machine Learning · Computer Science 2026-05-14 Alexander Geiger , Lars Wagner , Daniel Rueckert , Alois Knoll , Dirk Wilhelm , Alissa Jell

Healthcare models are transitioning from unimodal prediction toward multimodal reasoning over heterogeneous diagnostic inputs. In computational pathology, for complex tumor subtypes where morphology alone can be challenging to distinguish,…

Process mining techniques help to improve processes using event data. Such data are widely available in information systems. However, they often contain highly sensitive information. For example, healthcare information systems record event…

Databases · Computer Science 2021-05-26 Majid Rafiei , Wil M. P. van der Aalst

Graph mining to extract interesting components has been studied in various guises, e.g., communities, dense subgraphs, cliques. However, most existing works are based on notions of frequency and connectivity and do not capture subjective…

Social and Information Networks · Computer Science 2016-08-15 Hao Wu , Maoyuan Sun , Jilles Vreeken , Nikolaj Tatti , Chris North , Naren Ramakrishnan

Confusion often arises when attempting to articulate target estimand(s) of a clinical trial in plain language. We aim to rectify this confusion by using a type of causal graph called the Single-World Intervention Graph (SWIG) to provide a…

Methodology · Statistics 2022-06-06 Alex Ocampo , Jemar R. Bather

We present a foundation model-derived method to identify highly informative tokens and events in electronic health records. Our approach considers incoming data in the entire context of a patient's hospitalization and so can flag anomalous…

Machine Learning · Computer Science 2025-07-31 Michael C. Burkhart , Bashar Ramadan , Luke Solo , William F. Parker , Brett K. Beaulieu-Jones

Most existing time-to-event methods focus on either single-event or competing-risks settings, leaving multi-event scenarios relatively underexplored. In many healthcare applications, for example, a patient may experience multiple clinical…

Machine Learning · Computer Science 2025-11-20 Christian Marius Lillelund , Ali Hossein Gharari Foomani , Weijie Sun , Shi-ang Qi , Russell Greiner

The rapid advancement of high-throughput sequencing and other assay technologies has resulted in the generation of large and complex multi-omics datasets, offering unprecedented opportunities for advancing precision medicine strategies.…

Quantitative Methods · Quantitative Biology 2025-01-30 Ana R. Baião , Zhaoxiang Cai , Rebecca C Poulos , Phillip J. Robinson , Roger R Reddel , Qing Zhong , Susana Vinga , Emanuel Gonçalves

The mining of adverse drug events (ADEs) is pivotal in pharmacovigilance, enhancing patient safety by identifying potential risks associated with medications, facilitating early detection of adverse events, and guiding regulatory…

Artificial Intelligence · Computer Science 2024-10-04 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Aman Chadha , Samrat Mondal

Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provides a deeper understanding of brain disorders at cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 Gabriel Jimenez , Daniel Racoceanu

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…

Artificial Intelligence · Computer Science 2026-03-03 Shuheng Chen , Namratha Patil , Haonan Pan , Angel Hsing-Chi Hwang , Yao Du , Ruishan Liu , Jieyu Zhao

Intention-oriented process mining is based on the belief that the fundamental nature of processes is mostly intentional (unlike activity-oriented process) and aims at discovering strategy and intentional process models from event-logs…

Software Engineering · Computer Science 2015-07-07 Ashish Sureka

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

Machine Learning · Computer Science 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Understanding the latent processes from Electronic Medical Records could be a game changer in modern healthcare. However, the processes are complex due to the interaction between at least three dynamic components: the illness, the care and…

Machine Learning · Computer Science 2017-11-23 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh