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Mechanical force regulates the formation and growth of cell-cell junctions. Cadherin is a prominent homotypic cell adhesion molecule that plays a crucial role in establishment of intercellular adhesion. It is known that the transmitted…

Biological Physics · Physics 2017-10-11 Mohammad Tehrani , Alireza Sarvestani

Interfacial instabilities in multicomponent fluidic systems are widespread in nature and in industrial processes, yet controlling their dynamics remains a challenge. Here, we present a strategy to actively tune Marangoni-driven…

Soft Condensed Matter · Physics 2025-05-30 Christoph Haessig , Mehdi Habibi , Uddalok Sen

A wide spectrum of electrokinetic studies is modelled as isothermal ones to expedite analysis even when such conditions may be extremely difficult to realize in practice. As a clear and novel departure from this trend, we address the case…

Fluid Dynamics · Physics 2016-04-27 Tanmay Ghonge , Jeevanjyoti Chakraborty , Ranabir Dey , Suman Chakraborty

Large cells often rely on cytoplasmic flows for intracellular transport, maintaining homeostasis, and positioning cellular components. Understanding the mechanisms of these flows is essential for gaining insights into cell function,…

Fluid Dynamics · Physics 2023-11-09 Brato Chakrabarti , Stanislav Y. Shvartsman , Michael J. Shelley

Spatiotemporal patterns in multicellular systems are important to understanding tissue dynamics, for instance, during embryonic development and disease. Here, we use a multiphase field model to study numerically the behavior of a…

Soft Condensed Matter · Physics 2025-02-13 Michael Chiang , Austin Hopkins , Benjamin Loewe , M. Cristina Marchetti , Davide Marenduzzo

Marangoni propulsion is a form of locomotion wherein an asymmetric release of surfactant by a body located at the surface of a liquid leads to its directed motion. We present in this paper a mathematical model for Marangoni propulsion in…

Fluid Dynamics · Physics 2012-12-06 Eric Lauga , Anthony M. J. Davis

Phase segregation triggered by selective evaporation can emerge in multicomponent systems, leading to complex physiochemical hydrodynamics. Recently, Li et al. (Phys. Rev. Lett., vol. 120, 2018, 224501) and Kim & Stone (J. Fluid Mech., vol.…

Fluid Dynamics · Physics 2022-08-24 Yaxing Li , Pengyu Lv , Christian Diddens , Detlef Lohse

The motion of a fluid induced by thermal gradients in the absence of driving forces is known as thermo-osmosis. The physical explanation of this phenomenon stems from the emergence of gradients in the tangential pressure due to the presence…

Statistical Mechanics · Physics 2024-11-13 Pietro Anzini , Zeno Filiberti , Alberto Parola

Theoretical models of evaporating droplets predict Marangoni flows orders of magnitude faster than those observed experimentally. While this discrepancy is often attributed to surface contamination, the underlying mechanism by which…

Migration of animal cells is based on the interplay between actin polymerization at the front, adhesion along the cell-substrate interface, and actomyosin contractility at the back. Active gel theory has been used before to demonstrate that…

Cell Behavior · Quantitative Biology 2024-12-11 Valentin Wössner , Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

The spreading of a pure, volatile liquid on a wettable substrate has been studied in extensive detail. Here we show that the addition of a miscible, non-volatile liquid can strongly alter the contact line dynamics and the final liquid…

Soft Condensed Matter · Physics 2020-02-19 Asher P. Mouat , Clay E. Wood , Justin E. Pye , Justin C. Burton

Cell migration is closely linked to cell shape, yet cell size is often assumed to remain constant. This assumption is challenged by recent experiments showing that cells undergo volume loss during spreading and swelling upon activation,…

Biological Physics · Physics 2025-05-28 Jonathan E. Ron , Ram M. Adar

We discuss several continuum cell-cell adhesion models based on the underlying microscopic assumptions. We propose an improvement on these models leading to sharp fronts and intermingling invasion fronts between different cell type…

Cell Behavior · Quantitative Biology 2019-01-11 Jose A. Carrillo , Hideki Murakawa , Makoto Sato , Hideru Togashi , Olena Trush

We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…

Analysis of PDEs · Mathematics 2025-04-04 José A. Carrillo , Tommaso Lorenzi , Fiona R. Macfarlane

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

Soft Condensed Matter · Physics 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi

We investigate two-phase flow in porous media and derive a two-scale model, which incorporates pore-scale phase distribution and surface tension into the effective behavior at the larger Darcy scale. The free-boundary problem at the pore…

Analysis of PDEs · Mathematics 2023-07-03 Mathis Kelm , Carina Bringedal , Bernd Flemisch

The statistical mechanics of equilibrium interfaces has been well-established for over a half century. In the last decade, a wealth of observations have made increasingly clear that a new perspective is required to describe interfaces…

Soft Condensed Matter · Physics 2025-04-21 Luke Langford , Ahmad K. Omar

Cells swimming in confined environments are attracted by surfaces. We measure the steady-state distribution of smooth-swimming bacteria (Escherichia coli) between two glass plates. In agreement with earlier studies, we find a strong…

Soft Condensed Matter · Physics 2008-10-02 Allison P. Berke , Linda Turner , Howard C. Berg , Eric Lauga

Many cells exhibit large-scale active circulation of their entire fluid contents, a process termed cytoplasmic streaming. This phenomenon is particularly prevalent in plant cells, often presenting strikingly regimented flow patterns. The…

Soft Condensed Matter · Physics 2013-08-30 Francis G. Woodhouse , Raymond E. Goldstein

We demonstrate how concepts of statistical mechanics of interacting particles can have important implications in the choice of interaction potentials to model qualitative properties of cell aggregates in theoretical biology. We illustrate…

Cell Behavior · Quantitative Biology 2017-06-29 J. A. Carrillo , A. Colombi , M. Scianna