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The detection and discrimination of molecular chirality are essential for advancing pharmaceutical and biological applications. While nanophotonic platforms offer a route to enhance chiral light-matter interactions, existing device concepts…

Optics · Physics 2025-11-21 Zhongjun Jiang , Soyaib Sohag , You Zhou

Chiral nanomaterials offer intriguing possibilities for novel electronic and chemical applications. Here, we report the discovery of an enantiomer-selective magnetoresistance effect in chiral gold nanocrystals. Based on precise control of…

Mesoscale and Nanoscale Physics · Physics 2025-03-03 Fengxia Wu , Ying Wang , Yufei Zhao , Zhenyu Yang , Yu Tian , Zuoti Xie , Wenxin Niu , Binghai Yan , Cunlan Guo

Here we highlight enantioselective optical gradient forces present in 3D structured optical vortex tweezing systems. One chiral force originates from the circular polarization of the light, while remarkably the other is independent of the…

Optics · Physics 2025-02-05 Kayn A Forbes , Dale Green

The discovery of the chiral induced spin selectivity effect has provided a novel tool to study how active physical and chemical mechanism may differ in chiral enantiomers, however, the origin of the effect itself is yet an open question. In…

Mesoscale and Nanoscale Physics · Physics 2026-04-17 J. Fransson

We study the excitation of asymmetric-top (including chiral) molecules by two-color femtosecond laser pulses. In the cases of non-chiral asymmetric-top molecules excited by an orthogonally polarized two-color pulse, we demonstrate,…

Optics · Physics 2021-09-16 Long Xu , Ilia Tutunnikov , Yehiam Prior , Ilya Sh. Averbukh

Chirality and chiral molecules are key elements in modern chemical and biochemical industries. Individual addressing, and the eventual separation of chiral enantiomers has been and still is an important elusive task in molecular physics and…

We study a two-dimensional chiral active crystal composed of underdamped chiral active particles. These particles, characterized by intrinsic handedness and persistence, interact via linear forces derived from harmonic potentials. Chirality…

Soft Condensed Matter · Physics 2024-12-25 Umberto Marini Bettolo Marconi , Lorenzo Caprini

The development of new methodologies for the selective synthesis of individual enantiomers is still one of the major challenges in synthetic chemistry. Many biomolecules, and therefore many pharmaceutical compounds, are indeed chiral. While…

Chemical Physics · Physics 2023-08-14 Rosario R. Riso , Enrico Ronca , Henrik Koch

Chirality, the absence of mirror symmetry, is a fundamental molecular property with far-reaching consequences from chemistry to biology. Yet enantiosensitive optical responses are very weak. Here, we introduce a theoretical framework in…

Optics · Physics 2026-01-12 Yang-Cheng Ye , Panpan Zhang , Ajay Jha , Fulu Zheng , Hong-Guang Duan

Detecting and controlling the chirality of materials play an essential role in exploring nature, providing new avenues for material creation, discrimination, and manipulation. In such tasks, chiral reagents are essential in defining or…

Chirality is ubiquitous in nature and of fundamental importance in science. The present work focuses on understanding the conditions required to modify the chirality during ultrafast electronic motion by bringing enantiomers…

Chemical Physics · Physics 2021-01-04 Sucharita Giri , Alexandra Maxi Dudzinski , Jean Christophe Tremblay , Gopal Dixit

Chiral excited electronic states of molecules have an intrinsic sense of handedness, or twist, and are the active component in energy efficient display technologies and in new photosynthetic routes to produce pharmaceuticals. Creating…

Chiral discrimination of enantiomeric biomolecules is vital in chemistry, biology, and medicine. Conventional methods, relying on circularly polarized light, face weak chiroptical signals and potential photodamage. Despite extensive efforts…

Quantum Physics · Physics 2026-01-21 Yiquan Yang , Xiaolong Hu , Wei Du , Shuhe Wu , Peiyu Yang , Guzhi Bao , Weiping Zhang

A highly-efficient method for optical detection and separation of left- and right-handed chiral molecules is presented. The method utilizes a closed-loop three-state system in which the population dynamics depends on the phases of the three…

Quantum Physics · Physics 2019-05-08 Nikolay V. Vitanov , Michael Drewsen

Optical fields can exert forces of chiral nature on molecules and nanoparticles, which would prove extremely valuable in the separation of enantiomers with pharmaceutical applications, yet it is inherently complex, and the varied frameworks…

We present an optical "enantio-selective switch", that, in two steps, turns a ("racemic") mixture of left-handed and right-handed chiral molecules into the enantiomerically pure state of interest. The optical switch is composed of an…

Quantum Physics · Physics 2009-11-07 Petr Král , Ioannis Thanopulos , Moshe Shapiro , Doron Cohen

We develop a mathematical formalism underlying the emergence of enantio-sensitive molecular orientation due to photoionization or photoexitation of chiral molecules. We consider geometric quantities such as the Berry connection and Berry…

Quantum Physics · Physics 2025-05-30 Aycke Roos , Pablo M. Maier , Andres F. Ordonez , Olga Smirnova

Chiral molecules are widespread in nature, playing a fundamental role in bio-chemical processes and in the origin of life itself. The observation of dynamics in chiral molecules is crucial for the understanding and control of the chiral…

Exceptional points (EPs) are remarkable spectral degeneracies in a non-Hermitian system's parameter space, where both eigenvalues and eigenstates coalesce. Here, we show that in non-Hermitian molecular chiral systems the position of EPs in…

Quantum Physics · Physics 2025-12-02 Nicola Mayer , Alexander Löhr , Nimrod Moiseyev , Misha Ivanov , Olga Smirnova

The development of efficient techniques to distinguish mirror images of chiral molecules (enantiomers) is very important in both chemistry and physics. Enantiomers share most molecular properties except, for instance, the absorption of…

Chemical Physics · Physics 2023-07-11 Rosario R. Riso , Laura Grazioli , Enrico Ronca , Tommaso Giovannini , Henrik Koch