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The doubly robust estimator, which models both the propensity score and outcomes, is a popular approach to estimate the average treatment effect in the potential outcome setting. The primary appeal of this estimator is its theoretical…

Methodology · Statistics 2024-09-11 Kaoru Babasaki , Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn

Many research questions -- particularly those in environmental health -- do not involve binary exposures. In environmental epidemiology, this includes multivariate exposure mixtures with nondiscrete components. Causal inference estimands…

We propose a novel exponentially-modified Gaussian (EMG) mixture residual model. The EMG mixture is well suited to model residuals that are contaminated by a distribution with positive support. This is in contrast to commonly used robust…

Machine Learning · Statistics 2019-02-18 Sebastian Ament , John Gregoire , Carla Gomes

Causal inference methods have been applied in various fields where researchers want to estimate treatment effects. In traditional causal inference settings, one assumes that the outcome of a unit does not depend on treatments of other…

Methodology · Statistics 2022-09-05 Kelly Kung , Daniel L. Sussman

Background: Variables in epidemiological observational studies are commonly subject to measurement error and misclassification, but the impact of such errors is frequently not appreciated or ignored. As part of the STRengthening Analytical…

Urban pollution poses serious health risks, particularly in relation to traffic-related air pollution, which remains a major concern in many cities. Vehicle emissions contribute to respiratory and cardiovascular issues, especially for…

Machine Learning · Computer Science 2024-12-30 Sen Yan , David J. O'Connor , Xiaojun Wang , Noel E. O'Connor , Alan F. Smeaton , Mingming Liu

Observational causal inference is useful for decision making in medicine when randomized clinical trials (RCT) are infeasible or non generalizable. However, traditional approaches fail to deliver unconfounded causal conclusions in practice.…

No unmeasured confounding is a common assumption when reasoning about counterfactual outcomes, but such an assumption may not be plausible in observational studies. Sensitivity analysis is often employed to assess the robustness of causal…

Methodology · Statistics 2025-08-20 Abhinandan Dalal , Eric J. Tchetgen Tchetgen

Particulate matter (PM) is linked to adverse health outcomes, yet the roles of specific PM components and their modification by extreme temperature remain unclear. We examined short-term associations between ten PM chemical components and…

Atmospheric and Oceanic Physics · Physics 2026-03-03 Xiaolu Zhang , Anna Font , Anja Tremper , Max Priestman , Shawn Y. Lee , David C. Green , Dimitris Evangelopoulos , Gang I. Chen

Many time-to-event studies are complicated by the presence of competing risks. Such data are often analyzed using Cox models for the cause specific hazard function or Fine-Gray models for the subdistribution hazard. In practice regression…

Methodology · Statistics 2018-07-02 Rodney Sparapani , Brent R. Logan , Robert E. McCulloch , Purushottam W. Laud

Causal representation learning (CRL) aims to learn low-dimensional causal latent variables from high-dimensional observations. While identifiability has been extensively studied for CRL, estimation has been less explored. In this paper, we…

Machine Learning · Statistics 2026-03-24 Bohan Wu , Julius von Kügelgen , David M. Blei

Functional data are increasingly prevalent in biomedical research. While functional data analysis has been established for decades, causal inference with functional treatments remains largely unexplored. Existing methods typically focus on…

Methodology · Statistics 2026-02-11 Ziren Jiang , Erjia Cui , Jared D. Huling

We study identifying and estimating the causal effect of a treatment variable on a long-term outcome using data from an observational and an experimental domain. The observational data are subject to unobserved confounding. Furthermore,…

In this paper, we propose a robust method to estimate the average treatment effects in observational studies when the number of potential confounders is possibly much greater than the sample size. We first use a class of penalized…

Methodology · Statistics 2018-12-21 Yang Ning , Sida Peng , Kosuke Imai

Bayesian Causal Forests (BCF) is a causal inference machine learning model based on a highly flexible non-parametric regression and classification tool called Bayesian Additive Regression Trees (BART). Motivated by data from the Trends in…

Machine Learning · Statistics 2023-03-10 Nathan McJames , Andrew Parnell , Yong Chen Goh , Ann O'Shea

Causal effect estimation for dynamic treatment regimes (DTRs) contributes to sequential decision making. However, censoring and time-dependent confounding under DTRs are challenging as the amount of observational data declines over time due…

Machine Learning · Statistics 2021-09-27 Adi Lin , Jie Lu , Junyu Xuan , Fujin Zhu , Guangquan Zhang

Healthcare decision-making requires not only accurate predictions but also insights into how factors influence patient outcomes. While traditional Machine Learning (ML) models excel at predicting outcomes, such as identifying high risk…

Machine Learning · Computer Science 2025-01-28 Sheresh Zahoor , Pietro Liò , Gaël Dias , Mohammed Hasanuzzaman

Matching is one of the simplest approaches for estimating causal effects from observational data. Matching techniques compare the observed outcomes across pairs of individuals with similar covariate values but different treatment statuses…

Artificial Intelligence · Computer Science 2024-09-23 Abhishek Dalvi , Neil Ashtekar , Vasant Honavar

We consider the problem of estimating the average treatment effect (ATE) in a semi-supervised learning setting, where a very small proportion of the entire set of observations are labeled with the true outcome but features predictive of the…

Methodology · Statistics 2020-10-27 David Cheng , Ashwin Ananthakrishnan , Tianxi Cai

Uncovering causal effects in multiple treatment setting at various levels of granularity provides substantial value to decision makers. Comprehensive machine learning approaches to causal effect estimation allow to use a single causal…

Econometrics · Economics 2025-02-17 Michael Lechner , Jana Mareckova
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