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In diffusion-based molecular communication, information is transferred from a transmitter to a receiver using molecular carriers. The low achievable data rate is the main disadvantage of diffusion-based molecular over radio-based…

Emerging Technologies · Computer Science 2018-09-18 Tayyebeh Jahani-Nezhad , Foroogh S. Tabataba

We develop a convergent reaction-drift-diffusion master equation (CRDDME) to facilitate the study of reaction processes in which spatial transport is influenced by drift due to one-body potential fields within general domain geometries. The…

Numerical Analysis · Mathematics 2025-01-22 Samuel A. Isaacson , Ying Zhang

Approximate Bayesian Computation is widely used to infer the parameters of discrete-state continuous-time Markov networks. In this work, we focus on models that are governed by the Chemical Master Equation (the CME). Whilst originally…

Quantitative Methods · Quantitative Biology 2020-01-10 Christopher Lester

Data transmission rate in molecular communication systems can be improved by using multiple transmitters and receivers. In molecular multiple-input multiple-output (MIMO) systems which use only single type of molecules, the performance at…

Information Theory · Computer Science 2019-04-23 Nithin V. Sabu , Neeraj Varshney , Abhishek K. Gupta

In this paper, a cooperative diffusion-based molecular communication system is considered where distributed receivers collaboratively determine a transmitter's signal. In this system, the receivers first make local hard decisions about the…

Information Theory · Computer Science 2017-03-20 Yuting Fang , Adam Noel , Nan Yang , Andrew W. Eckford , Rodney A. Kennedy

A unified description of full reaction channels in low-energy heavy-ion collisions is a great challenge. Although the theoretical models based on the dinuclear system (DNS) concept have been successfully employed in multinucleon transfer…

Nuclear Theory · Physics 2025-09-05 Zehong Liao , Yu Yang , Zepeng Gao , Jun Su , Long Zhu

Binding and unbinding of ligands to specific sites of a macromolecule are one of the most elementary molecular interactions inside the cell that embody the computational processes of biological regulations. The interaction between…

Molecular Networks · Quantitative Biology 2011-11-10 Hidenori Kimura , Hiroyuki Okano , Reiko J. Tanaka

The classical models for irreversible diffusion-influenced reactions can be derived by introducing absorbing boundary conditions to over-damped continuous Brownian motion (BM) theory. As there is a clear corresponding stochastic process,…

Statistical Mechanics · Physics 2016-10-13 Mauricio J. Del Razo , Hong Qian

Analytical modeling of field-assisted molecular communication under dynamic electric fields is fundamentally challenging due to the coupling between stochastic transport and complex boundary geometries, which renders conventional partial…

Information Theory · Computer Science 2026-04-02 Po-Chun Chou , Yen-Chi Lee , Chun-An Yang , Chia-Han Lee , Ping-Cheng Yeh

In this paper, we consider the diffusive molecular communication channel between a transmitter nano-machine and a receiver nano-machine in a fluid environment. The information molecules released by the transmitter nano-machine into the…

Emerging Technologies · Computer Science 2016-11-17 Arman Ahmadzadeh , Hamidreza Arjmanidi , Andreas Burkovski , Robert Schober

Synthetic molecular communication (SMC) is a key enabler for future healthcare systems in which Internet of Bio-Nano-Things (IoBNT) devices facilitate the continuous monitoring of a patient's biochemical signals. To close the loop between…

Machine Learning · Computer Science 2025-07-11 Sebastian Lotter , Elisabeth Mohr , Andrina Rutsch , Lukas Brand , Francesca Ronchi , Laura Díaz-Marugán

Steady state is an essential concept in reaction networks. Its stability reflects fundamental characteristics of several biological phenomena such as cellular signal transduction and gene expression. Because biochemical reactions occur at…

Molecular Networks · Quantitative Biology 2019-04-19 Tan Van Vu , Yoshihiko Hasegawa

Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective response, or amplify noise to generate distinct phenotypic…

Molecular Networks · Quantitative Biology 2019-09-24 David T. Gonzales , T-Y Dora Tang , Christoph Zechner

The dynamics of stochastic reaction networks within cells are inevitably modulated by factors considered extrinsic to the network such as for instance the fluctuations in ribsome copy numbers for a gene regulatory network. While several…

Quantitative Methods · Quantitative Biology 2015-06-19 Christoph Zechner , Heinz Koeppl

One of the important applications of molecular communication is the targeted drug delivery process in which the drug molecules are released toward the target (receiver) in a way that the side effects are minimized in the human body. As the…

Information Theory · Computer Science 2021-12-28 Roya Paridar , Nader Mokari , Eduard Jorswieck , Mohammad Reza Javan

The notion of synthetic molecular communication (MC) refers to the transmission of information via signaling molecules and is foreseen to enable innovative medical applications in the human cardiovascular system (CVS). Crucially, the design…

Quantitative Methods · Quantitative Biology 2025-12-03 Timo Jakumeit , Lukas Brand , Jens Kirchner , Robert Schober , Sebastian Lotter

To achieve continuous massive data transmission with significantly reduced data payload, the users can adopt semantic communication techniques to compress the redundant information by transmitting semantic features instead. However, current…

Signal Processing · Electrical Eng. & Systems 2024-01-30 Youcheng Zeng , Xinxin He , Xu Chen , Haonan Tong , Zhaohui Yang , Yijun Guo , Jianjun Hao

Understanding molecular structure, dynamics, and reactivity requires bridging processes that occur across widely separated time scales. Conventional molecular dynamics simulations provide atomistic resolution, but their femtosecond time…

Chemical Physics · Physics 2025-10-10 Juan Viguera Diez , Mathias Schreiner , Simon Olsson

Stochastic reaction networks with mass-action kinetics provide a useful framework for understanding processes -- biochemical and otherwise -- in homogeneous environments. However, cellular reactions are often compartmentalized, either at…

Probability · Mathematics 2026-05-01 David F. Anderson , Aidan S. Howells , Diego Rojas La Luz

Reaction-diffusion models are used to describe systems in fields as diverse as physics, chemistry, ecology and biology. The fundamental quantities in such models are individual entities such as atoms and molecules, bacteria, cells or…

Computational Physics · Physics 2016-03-02 Fabian Spill , Pilar Guerrero , Tomas Alarcon , Philip K. Maini , Helen Byrne