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Stochastic reaction networks are a fundamental model to describe interactions between species where random fluctuations are relevant. The master equation provides the evolution of the probability distribution across the discrete state space…

Molecular Networks · Quantitative Biology 2021-06-15 Tabea Waizmann , Luca Bortolussi , Andrea Vandin , Mirco Tribastone

The reaction-diffusion master equation (RDME) is a lattice-based stochastic model for spatially resolved cellular processes. It is often interpreted as an approximation to spatially continuous reaction-diffusion models, which, in the limit…

Statistical Mechanics · Physics 2022-01-11 Alberto Montefusco , Christof Schütte , Stefanie Winkelmann

Diffusion-based molecular communication over nanonetworks is an emerging communication paradigm that enables nanomachines to communicate by using molecules as the information carrier. For such a communication paradigm, Concentration Shift…

Information Theory · Computer Science 2014-01-20 Subodh Pudasaini , Seokjoo Shin , Kyung Sup Kwak

Stochastic evolution of Chemical Reactions Networks (CRNs) over time is usually analysed through solving the Chemical Master Equation (CME) or performing extensive simulations. Analysing stochasticity is often needed, particularly when some…

Logic in Computer Science · Computer Science 2015-09-11 Luca Laurenti , Luca Cardelli , Marta Kwiatkowska

This paper focuses on molecular communication (MC) systems using two types of signaling molecules which may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can…

Information Theory · Computer Science 2019-07-25 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

Stochastic reaction network models are widely utilized in biology and chemistry to describe the probabilistic dynamics of biochemical systems in general, and gene interaction networks in particular. Most often, statistical analysis and…

Quantitative Methods · Quantitative Biology 2017-10-18 Eugenio Cinquemani

The notion of synthetic molecular communication (MC) refers to the transmission of information via molecules and is largely foreseen for use within the human body, where traditional electromagnetic wave (EM)-based communication is…

Emerging Technologies · Computer Science 2025-04-16 Timo Jakumeit , Lukas Brand , Jens Kirchner , Robert Schober , Sebastian Lotter

The mesoscopic reaction-diffusion master equation (RDME) is a popular modeling framework, frequently applied to stochastic reaction-diffusion kinetics in systems biology. The RDME is derived from assumptions about the underlying physical…

Numerical Analysis · Mathematics 2015-06-23 Stefan Hellander , Andreas Hellander , Linda Petzold

Molecular communication in nature can incorporate a large number of nano-things in nanonetworks as well as demonstrate how nano-things communicate. This paper presents molecular communication where transmit nanomachines deliver information…

Information Theory · Computer Science 2019-11-05 Dung Phuong Trinh , Youngmin Jeong , Hyundong Shin , Moe Z. Win

To model bio-chemical reaction systems with diffusion one can either use stochastic, microscopic reaction-diffusion master equations or deterministic, macroscopic reaction-diffusion system. The connection between these two models is not…

Analysis of PDEs · Mathematics 2023-06-21 Malcolm Egan , Bao Quoc Tang

The noisy dynamics of chemical systems is commonly studied using either the chemical master equation (CME) or the chemical Fokker-Planck equation (CFPE). The latter is a continuum approximation of the discrete CME approach. We here show…

Quantitative Methods · Quantitative Biology 2015-06-22 Andrew Duncan , Shuohao Liao , Tomas Vejchodsky , Radek Erban , Ramon Grima

One of the main challenges in diffusion-based molecular communication is dealing with the non-linearity of reaction-diffusion chemical equations. While numerical methods can be used to solve these equations, a change in the input signals or…

Information Theory · Computer Science 2021-06-04 Hamidreza Abin , Amin Gohari , Masoumeh Nasiri-Kenari

This paper focuses on molecular communication (MC) systems where the signaling molecules may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can realize the concept…

Information Theory · Computer Science 2017-11-02 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

Mathematical modeling is now used commonly in the analysis of signaling networks. With advances in high resolution microscopy, the spatial location of different signaling molecules and the spatio-temporal dynamics of signaling microdomains…

Subcellular Processes · Quantitative Biology 2016-07-26 Jasmine Nirody , Padmini Rangamani

The notion of entropy is shared between statistics and thermodynamics, and is fundamental to both disciplines. This makes statistical problems particularly suitable for reaction network implementations. In this paper we show how to perform…

Molecular Networks · Quantitative Biology 2017-04-07 Muppirala Viswa Virinchi , Abhishek Behera , Manoj Gopalkrishnan

We investigate theoretically the stochastic dynamics of Resonance Electronic Energy Transfer (RET), in a bi-dimensional overexcited ensemble of donor and acceptor molecules. We find that, after initial optical excitation of all the donors,…

Mesoscale and Nanoscale Physics · Physics 2023-11-27 R. Avriller , A. Marché , G. Jonusauskas

Information delivery using chemical molecules is an integral part of biology at multiple distance scales and has attracted recent interest in bioengineering and communication. The collective signal strength at the receiver (i.e., the…

Information Theory · Computer Science 2016-08-04 Yansha Deng , Adam Noel , Weisi Guo , Arumugam Nallanathan , Maged Elkashlan

Turing patterns can be observed in reaction-diffusion systems where chemical species have different diffusion constants. In recent years, several studies investigated the effects of noise on Turing patterns and showed that the parameter…

Computational Physics · Physics 2013-10-30 Yang Cao , Radek Erban

A molecular communication channel is determined by the received signal. Received signal models form the basis for studies focused on modulation, receiver design, capacity, and coding depend on the received signal models. Therefore, it is…

Emerging Technologies · Computer Science 2016-11-21 H. Birkan Yilmaz , Changmin Lee , Yae Jee Cho , Chan-Byoung Chae

The reaction-diffusion master equation (RDME) is a model that allows for efficient on-lattice simulation of spatially resolved stochastic chemical kinetics. Compared to off-lattice hard-sphere simulations with Brownian Dynamics (BD) or…

Numerical Analysis · Mathematics 2017-09-06 Stefan Hellander , Andreas Hellander , Linda Petzold