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Functional magnetic resonance imaging (fMRI) has been widely utilized to study the motor deficits and rehabilitation following stroke. In particular, functional connectivity(FC) analyses with fMRI at rest can be employed to reveal the…

Neurons and Cognition · Quantitative Biology 2023-01-19 Kaichao Wu , Beth Jelfs , Katrina Neville , John Q. Fang

Parkinson's disease (PD) is a common and complex neurodegenerative disorder with 5 stages in the Hoehn and Yahr scaling. Given the heterogeneity of PD, it is challenging to classify early stages 1 and 2 and detect brain function…

Neurons and Cognition · Quantitative Biology 2022-07-22 Xueqi Guo , Sule Tinaz , Nicha C. Dvornek

Drug repurposing has historically been an economically infeasible process for identifying novel uses for abandoned drugs. Modern machine learning has enabled the identification of complex biochemical intricacies in candidate drugs; however,…

Machine Learning · Computer Science 2025-09-16 Luke Delzer , Robert Kroleski , Ali K. AlShami , Jugal Kalita

Clustering trajectory data attracted considerable attention in the last few years. Most of prior work assumed that moving objects can move freely in an euclidean space and did not consider the eventual presence of an underlying road network…

Machine Learning · Computer Science 2013-10-22 Mohamed Khalil El Mahrsi , Fabrice Rossi

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Recent randomised clinical trials have shown that patients with ischaemic stroke {due to occlusion of a large intracranial blood vessel} benefit from endovascular thrombectomy. However, predicting outcome of treatment in an individual…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Zeynel A. Samak , Philip Clatworthy , Majid Mirmehdi

Gradient-boosted trees achieve strong performance on tabular data, yet often leave a long tail of poorly predicted instances. We introduce a Trajectory-based Difficulty Score (TDS), an instance-level difficulty estimator for boosted…

Machine Learning · Computer Science 2026-05-26 Tomer Lavi , Bracha Shapira , Nadav Rappoport

Complex networks are a powerful modeling tool, allowing the study of countless real-world systems. They have been used in very different domains such as computer science, biology, sociology, management, etc. Authors have been trying to…

Social and Information Networks · Computer Science 2014-02-04 Burcu Kantarcı , Vincent Labatut

Modern navigation services often provide multiple paths connecting the same source and destination for users to select. Hence, ranking such paths becomes increasingly important, which directly affects the service quality. We present…

Machine Learning · Computer Science 2019-07-10 Sean Bin Yang , Bin Yang

Rapid triage of suspected stroke needs accurate, bedside-deployable tools; EEG is promising but underused at first contact. We present an adaptive multitask EEG classifier that converts 32-channel signals to power spectral density features…

Machine Learning · Computer Science 2025-11-13 Shakeel Abdulkareem , Bora Yimenicioglu , Khartik Uppalapati , Aneesh Gudipati , Adan Eftekhari , Saleh Yassin

In this study, we utilized statistical analysis and machine learning methods to examine whether rehabilitation exercises can improve patients post-stroke functional abilities, as well as forecast the improvement in functional abilities. Our…

Interpreting large volumes of high-dimensional, unlabeled data in a manner that is comprehensible to humans remains a significant challenge across various domains. In unsupervised healthcare data analysis, interpreting clustered data can…

Machine Learning · Computer Science 2025-06-17 Shehroz S. Khan , Ali Abedi , Charlene H. Chu

Identifying stimulus-driven neural activity patterns is critical for studying the neural basis of cognition. This can be particularly challenging in intracranial datasets, where electrode locations typically vary across patients. This…

Neurons and Cognition · Quantitative Biology 2022-02-07 Jeremy R. Manning

Multimorbidity, or the presence of several medical conditions in the same individual, has been increasing in the population, both in absolute and relative terms. However, multimorbidity remains poorly understood, and the evidence from…

Segmentation of focal (localized) brain pathologies such as brain tumors and brain lesions caused by multiple sclerosis and ischemic strokes are necessary for medical diagnosis, surgical planning and disease development as well as other…

Computer Vision and Pattern Recognition · Computer Science 2017-01-25 Mohammad Havaei , Nicolas Guizard , Hugo Larochelle , Pierre-Marc Jodoin

Tremor is a key diagnostic feature of Parkinson's Disease (PD), Essential Tremor (ET), and other central nervous system (CNS) disorders. Clinicians or trained raters assess tremor severity with TETRAS scores by observing patients. Lacking…

Computer Vision and Pattern Recognition · Computer Science 2021-05-05 Li Zhang , Vijay Yadav , Vidya Koesmahargyo , Anzar Abbas , Isaac Galatzer-Levy

Objective: Syncope is a sudden loss of consciousness with loss of postural tone and spontaneous recovery; it is a common condition, albeit one that is challenging to accurately diagnose. Uncertainties about the triggering mechanisms and…

Quantitative Methods · Quantitative Biology 2016-09-08 Joseph Hart , Jesper Mehlsen , Christian H. Olsen , Mette Sofie Olufsen , Pierre Gremaud

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Background and Objectives: Multidrug Resistance (MDR) is a critical global health issue, causing increased hospital stays, healthcare costs, and mortality. This study proposes an interpretable Machine Learning (ML) framework for MDR…