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Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

Quantitative Methods · Quantitative Biology 2020-08-04 Sanjukta Krishnagopal

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

Applications · Statistics 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

Stroke order and velocity are helpful features in the fields of signature verification, handwriting recognition, and handwriting synthesis. Recovering these features from offline handwritten text is a challenging and well-studied problem.…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Taylor Archibald , Mason Poggemann , Aaron Chan , Tony Martinez

Machine learning offers great potential for automated prediction of post-stroke symptoms and their response to rehabilitation. Major challenges for this endeavour include the very high dimensionality of neuroimaging data, the relatively…

Artificial Intelligence · Computer Science 2023-10-31 Adam White , Margarita Saranti , Artur d'Avila Garcez , Thomas M. H. Hope , Cathy J. Price , Howard Bowman

Treatment of cancer involves heterogeneous, complex care pathways. The relationship between these longitudinal trajectories, baseline mental health, and prognostic outcomes remains poorly understood. We introduce an interpretable…

The brain continually reorganizes its functional network to adapt to post-stroke functional impairments. Previous studies using static modularity analysis have presented global-level behavior patterns of this network reorganization.…

Computation · Statistics 2024-03-25 Kaichao Wu , Beth Jelfs , Katrina Neville , Wenzhen He , Qiang Fang

Background: The brain's functional network constantly adapts to external changes. However, the mechanisms underlying this dynamic adaptive behavior in stroke patients with motor injuries and its role in post-stroke motor recovery remain…

Neurons and Cognition · Quantitative Biology 2024-01-18 Kaichao Wu , Beth Jelfs , Katrina Neville , Qiang Fang

One third of stroke survivors have language difficulties. Emerging evidence suggests that their likelihood of recovery depends mainly on the damage to language centers. Thus previous research for predicting language recovery post-stroke has…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Yusuf H. Roohani , Noor Sajid , Pranava Madhyastha , Cathy J. Price , Thomas M. H. Hope

Stroke is known as a major global health problem, and for stroke survivors it is key to monitor the recovery levels. However, traditional stroke rehabilitation assessment methods (such as the popular clinical assessment) can be subjective…

Signal Processing · Electrical Eng. & Systems 2022-12-27 Xi Chen , Yu Guan , Jian Qing Shi , Xiu-Li Du , Janet Eyre

Stroke is one of the leading causes of disability worldwide. The efficacy of recovery is determined by a variety of factors, including patient adherence to rehabilitation programs. One way to increase patient adherence to their…

Human-Computer Interaction · Computer Science 2024-02-20 Alicia Ouskine , Adrian D. C. Chan , Fateme Rajabiyazdi

Background: Identifying and characterising the longitudinal patterns of multimorbidity associated with stroke is needed to better understand patients' needs and inform new models of care. Methods: We used an unsupervised patient-oriented…

The identification of phenotypes within complex diseases or syndromes is a fundamental component of precision medicine, which aims to adapt healthcare to individual patient characteristics. Postoperative delirium (POD) is a complex…

Traumatic Brain Injury (TBI) presents a broad spectrum of clinical presentations and outcomes due to its inherent heterogeneity, leading to diverse recovery trajectories and varied therapeutic responses. While many studies have delved into…

Machine Learning · Computer Science 2024-08-22 Hamid Ghaderi , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

Cerebrovascular accident, or commonly known as stroke, is an acute disease with extreme impact on patients and healthcare systems and is the second largest cause of death worldwide. Fast and precise stroke lesion detection and location is…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Chuanlong Li

As our population ages, neurological impairments and degeneration of the musculoskeletal system yield gait abnormalities, which can significantly reduce quality of life. Gait rehabilitative therapy has been widely adopted to help patients…

Computer Vision and Pattern Recognition · Computer Science 2017-02-02 Ioannis Papavasileiou , Wenlong Zhang , Xin Wang , Jinbo Bi , Li Zhang , Song Han

Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials. In this paper we design a…

Applications · Statistics 2016-02-24 Abhishek Sengupta , Vaibhav Rajan , Sakyajit Bhattacharya , G R K Sarma

Trace clustering has increasingly been applied to find homogenous process executions. However, current techniques have difficulties in finding a meaningful and insightful clustering of patients on the basis of healthcare data. The resulting…

Databases · Computer Science 2020-01-13 Xixi Lu , Seyed Amin Tabatabaei , Mark Hoogendoorn , Hajo A. Reijers

Automatic and accurate lesion segmentation is critical for clinically estimating the lesion statuses of stroke diseases and developing appropriate diagnostic systems. Although existing methods have achieved remarkable results, further…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Xiuquan Du , Kunpeng Ma , Yuhui Song

Brain stroke is a leading cause of mortality and long-term disability worldwide, underscoring the need for precise and rapid prediction techniques. Computed Tomography (CT) scan is considered one of the most effective methods for diagnosing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Md. Sabbir Hossen , Eshat Ahmed Shuvo , Shibbir Ahmed Arif , Pabon Shaha , Anichur Rahman , Md. Saiduzzaman , Fahmid Al Farid , Hezerul Abdul Karim , Abu Saleh Musa Miah

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

Machine Learning · Computer Science 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren
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